Results 131 to 140 of about 359,344 (313)
Optoelectronic Interfaces for Nongenetic Modulation of Excitable Tissues
Small Methods, EarlyView.This review summarizes recent advances in nongenetic optoelectronic technologies for the modulation of excitable biotissues, covering material selection, device design, and working principles, as well as characterization methods. Representative applications in in vitro and in vivo models of the cardiac, central, and peripheral nervous systems are ...
Qi Wang, Jinghua Li
wiley +1 more source
Prospective evaluation of low-dose ketoconazole plus hydrocortisone in docetaxel pre-treated castration-resistant prostate cancer patients. [PDF]
, 2015 BackgroundKetoconazole is a well-known CYP17-targeted systemic treatment for castration-resistant prostate cancer (CRPC). However, most of the published data has been in the pre-chemotherapy setting; its efficacy in the post-chemotherapy setting has not ...
Beckett, LA +6 more
core
Multiscale Engineering of Ion‐Conducting Gels for Sustainable Bioelectronic Systems
Small Methods, EarlyView.This review highlights multiscale engineering strategies for ion‐conducting gels aimed at achieving sustainable bioelectronic systems. It systematically examines material‐level, device‐level, and system‐level approaches to ensure long‐term stability and functional integrity under physiological conditions, integrating molecular design, device ...
Ji Hong Kim +6 more
wiley +1 more source
Medical Marijuana-Induced Tacrolimus Toxicity. [PDF]
, 2019 As both recreational and therapeutic marijuana use increases in the US, more attention is being paid to its direct medical and psychoactive effects. One crucial dimension is the potential for marijuana or marijuana-derived therapies to interact with ...
Chism, Keira, Moadel, Daniel
core +1 more source
VIEW, EarlyView.Inhibiting the SUMOylation modification of TRPM4 can prevent the vascular endothelial damage caused by ATO. Inhibition of TRPM4 SUMOylation, either pharmacologically by GA or genetically by the K618R mutation, protects against ATO‐induced vascular endothelial damage.
Ting‐Ting Tong +18 more
wiley +1 more source
Inflammatory cytokines and atrial fibrillation: current and prospective views
Journal of Inflammation Research, 2010 Hadi AR Hadi, Alawi A Alsheikh-Ali, Wael AL Mahmeed, Jassim M Al SuwaidiInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, United Arab EmiratesAbstract: Atrial fibrillation (AF) is the most common sustained arrhythmia and a ­ ...
Hadi AR Hadi +3 more
doaj
Addiction, EarlyView.Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens +7 more
wiley +1 more source
From the INVICTUS Trial to Current Considerations: It’s Not Time to Retire Vitamin K Inhibitors Yet!
PharmaceuticalsAtrial fibrillation (AF) is a common arrhythmia in clinical practice, and oral anticoagulation is the cornerstone of stroke prevention in AF. Direct oral anticoagulants (DOAC) significantly reduce the incidence of intracerebral hemorrhage with preserved ...
Akshyaya Pradhan +2 more
doaj +1 more source
Addiction, EarlyView.Abstract Revived interest in psychedelic‐assisted therapies has also renewed focus on ibogaine, a psychoactive alkaloid, for its notable anti‐addictive potential. Evidence from observational, open‐label, and limited randomized placebo‐controlled trials indicates that ibogaine and its metabolite noribogaine reduce craving and withdrawal symptoms in ...
Tibor Markus Brunt
wiley +1 more source
Allergy, EarlyView.ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source