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Reactions Weekly, 2022 Amiodarone is one of the most commonly used anti-arrhythmic drugs. While the United States FDA has labeled amiodarone for the treatment of life-threatening ventricular arrhythmias, the drug is commonly used off-label to treat supraventricular ...
Florek, Jeffrey B, Girzadas, Daniel
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Amiodarone Hepatotoxicity [PDF]
Current Vascular Pharmacology, 2008 Potential hepatotoxicity related to amiodarone therapy is often a concern when deciding whether to initiate or continue treatment with this medication. While mostly associated with long-term oral administration of the drug, toxicity has also been reported early during intravenous administration and months after discontinuation of therapy.
Mohamed, Babatin +2 more
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Amiodarone-Induced Electrical Storm: A Nightmare in the Emergency Room [PDF]
, 2023 Drug-induced long QT syndrome (LQTS) is defined as prolonged corrected QT interval (QTc ≥460 ms) plus polymorphic ventricular arrhythmia fitting the description of torsades de pointes temporally associated with the administration of a drug or combination
Sousa, Maria João +4 more
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Anaesthesia and amiodarone [PDF]
Canadian Anaesthetists’ Society Journal, 1985 Two recent reports support and one report disputes the existence of dangerous interactions between the new benzofuran antiarrhythmic amiodarone and the anaesthetic state. We have reviewed our experience with 17 anaesthetics administered to 16 patients taking amiodarone. Haemodynamics and serum amiodarone levels were evaluated where available.
B A, Liberman, S J, Teasdale
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Identification of Responders to Amiodarone: Subgroup Analysis of the EMIAT Study [PDF]
, 2003 Clinical trials often judge the efficacy of a new treatment by comparing the survival patterns of patients who are randomly assigned to undergo the new or a standard/placebo treatment.
Kehl, V. +7 more
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Mitochondrial toxicity of drugs [PDF]
, 2008 The introduction of this thesis concentrates on the cellular energy supplier and an important instrument in mediating cell death, mitochondrion. First, an overview is given to explain the biochemical properties of this organelle.
Waldhauser, Katri Maria
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Autophagy alleviates amiodarone-induced hepatotoxicity. [PDF]
, 2020 Amiodarone is a widely used antiarrhythmic drug that can cause the development of steatohepatitis as well as liver fibrosis and cirrhosis. The molecular mechanisms of amiodarone-mediated liver injury remain largely unknown.
Schulze-Osthoff, Klaus +12 more
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Drug interactions and hepatotoxicity of clopidogrel [PDF]
, 2010 Clopidogrel (Plavix¨) is an antiplatelet drug, which is clinically used in combination with aspirin to reduce cardiovascular events in patients undergoing percutaneous coronary intervention or in patients suffering from acute coronary syndromes ...
Zahno, Anja-Christina
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Pulmonary Toxicity Secondary to Amiodarone Use [PDF]
, 2019 Amiodarone is an antiarrhythmic medication used for the treatment of ventricular tachycardia. In addition to unwanted effects in many tissues, one of the most important side effects of the drug is pulmonary toxicity.
Nagehan Aslan +5 more
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Journal of the Belgian Society of Radiology, 2010 Background: A 65-year-old male patient presented with progressive shortness of breath over the past 3 months, recently even at rest. He neither complained about fever nor about chest pain. The laboratory findings were normal with only a slight increase in leucocytes. A significant restrictive ventilation disorder was noted on plethysmography.
Bley, T A, François, C J
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