Results 31 to 40 of about 42,119 (250)
Pulmonary Toxicity Secondary to Amiodarone Use [PDF]
, 2019 Amiodarone is an antiarrhythmic medication used for the treatment of ventricular tachycardia. In addition to unwanted effects in many tissues, one of the most important side effects of the drug is pulmonary toxicity.
Nagehan Aslan +5 more
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Amiodarone-induced reversible and irreversible hepatotoxicity: two case reports
Journal of Medical Case Reports, 2018 Background Amiodarone is a highly effective treatment for supraventricular and ventricular tachyarrhythmia; however, it could be associated with several serious adverse effects, including liver injury.
Toyonobu Tsuda +12 more
doaj +1 more source
Lipid emulsion mitigates intravenous amiodarone toxicity in a rat model
Toxicology Communications, 2022 Introduction Our study investigated whether lipid emulsion therapy could act as an antidote for intravenous amiodarone toxicity in a rat model.Methods 20 rats were randomised to receive lipid emulsion (ILE) or saline. Rats were infused with amiodarone at
Rachael Stewart +5 more
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Mechanisms of hepatocellular toxicity associated with dronedarone and other mitochondrial toxicants [PDF]
, 2014 Idiosyncratic drug-induced liver injury is a rare toxic event that typically occurs at therapeutic doses, which are generally safe to the majority of patients.
Felser, Andrea Debora
core +1 more source
Journal of Arrhythmia, 2014 Background: Intravenous amiodarone is considered to be the first-line drug for the treatment of ventricular tachycardia or fibrillation. However, in Japan, nifekalant had been used before the introduction of amiodarone; therefore, most clinical studies ...
Mari Amino, MD, PhD +8 more
doaj +1 more source
Cardiomyocyte-Targeting Peptide to Deliver Amiodarone
Pharmaceutics, 2023 Background: Amiodarone is underutilized due to significant off-target toxicities. We hypothesized that targeted delivery to the heart would lead to the lowering of the dose by utilizing a cardiomyocyte-targeting peptide (CTP), a cell-penetrating peptide ...
Maliha Zahid +7 more
doaj +1 more source
Management of amiodarone-related thyroid problems
Therapeutic Advances in Endocrinology and Metabolism, 2011 Amiodarone is a highly effective and well-established antiarrrhythmic drug. It can be used to treat supraventricular and ventricular tachyarrhythmias and has the added advantage of being well tolerated in patients with impaired left ventricular systolic ...
Shashithej K. Narayana +2 more
doaj +1 more source
NF-κB inhibitor or NAC attenuates amiodarone-induced injury of human lung epithelial cell line BEAS-2B [PDF]
Jichu yixue yu linchuangObjective To investigate the mechanism of reactive oxygen species (ROS) and pyroptosis in amiodarone-induced lung epithelial cell injury. Methods The viability of cells treated with amiodarone, amiodarone+N-acetylcysteine(ROS inhibitor,NAC) and ...
JI Zezhao, ZHANG Qi, Abuduxukuer·ABULIMITI
doaj +1 more source
Local Use of Hydrogel with Amiodarone in Cardiac Surgery: Experiment and Translation to the Clinic
Gels, 2021 The objective of this study was to study the use of the hydrogel biopolymer based on sodium alginate (“Colegel”) with a drug substance—amiodarone—for the prevention of postoperative atrial fibrillation (POAF) in cardiac surgery.
Vladimir Shvartz +6 more
doaj +1 more source
Anaesthesia and amiodarone [PDF]
Canadian Anaesthetists’ Society Journal, 1985 Two recent reports support and one report disputes the existence of dangerous interactions between the new benzofuran antiarrhythmic amiodarone and the anaesthetic state. We have reviewed our experience with 17 anaesthetics administered to 16 patients taking amiodarone. Haemodynamics and serum amiodarone levels were evaluated where available.
B A, Liberman, S J, Teasdale
openaire +2 more sources