Results 21 to 30 of about 59,816 (256)

Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias [PDF]

, 2016
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) hold promise for assessment of drug-induced arrhythmias and are being considered for use under the comprehensive in vitro proarrhythmia assay (CiPA).
Blinova, Ksenia, Brock, Mathew, Chan, Dulciana, Chvatal, Stacie, Crumb, William J., Galeotti, Loriano, Hortigon-Vinagre, Maria P., Johannesen, Lars, Lyn-Cook, Beverly, Millard, Daniel, Pang, Li, Ross, James, Smith, Godfrey, Stockbridge, Norman, Stohlman, Jayna, Strauss, David G., Vicente, Jose, Zamora Rodriguez, Victor   +17 more
core   +1 more source

Atrial Fibrillation in Eight New World Camelids. [PDF]

, 2015
BackgroundThere is limited information on the incidence of clinical signs, concurrent illness and treatment options for atrial fibrillation (AF) in New World Camelids (NWC).ObjectiveDescribe clinical signs and outcome of AF in NWC.AnimalsEight New World ...
Bozorgmanesh, R, Estell, KE, Griffiths, LG, Magdesian, KG, Stern, JA, Swain, EA   +5 more
core   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Lipid emulsion mitigates intravenous amiodarone toxicity in a rat model

Toxicology Communications, 2022
Introduction Our study investigated whether lipid emulsion therapy could act as an antidote for intravenous amiodarone toxicity in a rat model.Methods 20 rats were randomised to receive lipid emulsion (ILE) or saline. Rats were infused with amiodarone at
Rachael Stewart, Verity Newman, Martyn Harvey, Mingtan Tang, Zimei Wu, Grant Cave   +5 more
doaj   +1 more source

Analysis of uncertainty in health care cost-effectiveness studies: an introduction to statistical issues and methods [PDF]

, 2002
Cost-effectiveness analysis is now an integral part of health technology assessment and addresses the question of whether a new treatment or other health care program offers good value for money.
A H Briggs, B J O’Brien, Department of Health and Aging Commonwealth of Australia, Fieller EC., Gold MR, Ontario Ministry of Health, Pratt JW, Stinnett AA   +7 more
core   +1 more source

Amiodarone pneumonitis

Journal of the Belgian Society of Radiology, 2010
Background: A 65-year-old male patient presented with progressive shortness of breath over the past 3 months, recently even at rest. He neither complained about fever nor about chest pain. The laboratory findings were normal with only a slight increase in leucocytes. A significant restrictive ventilation disorder was noted on plethysmography.
Bley, T A, François, C J
openaire   +5 more sources

Subclinical thyroid dysfunction and cognitive decline in old age [PDF]

, 2013
<p>Background: Subclinical thyroid dysfunction has been implicated as a risk factor for cognitive decline in old age, but results are inconsistent. We investigated the association between subclinical thyroid dysfunction and cognitive decline in the
A Pinchera, AE Hak, AJ Camm, AM Kanaya, Anton J. M. de Craen, AR Cappola, AW Weverling-Rijnsburger, CJ Packard, CT Sawin, D Nanchen, David J. Stott, E Hogervorst, G Ceresini, G Waldemar, I Klein, IM Bensenor, IP Casserly, J Auer, J Gussekloo, J Klubo-Gwiezdzinska, J Parle, J Shepherd, J. Wouter Jukema, Jacobijn Gussekloo, JJ Diez, JP Walsh, Liselotte W. Wijsman, LM Roberts, MI Surks, MP van Boxtel, N Rodondi, Nicolas Rodondi, Paul Welsh, Paula Soares, PJ Houx, PW Ladenson, R Jorde, R Luboshitzky, RP Peeters, Rudi G. J. Westendorp, S Kalmijn, S Stabouli, S Trompet, S Trompet, Simon P. Mooijaart, SP Mooijaart, Stella Trompet, T van Bemmel, WJ Hueston   +48 more
core   +5 more sources

Impact of amiodarone on plasma concentration of direct oral anticoagulant in patients with atrial fibrillation

Journal of the Formosan Medical Association, 2023
Background/purpose: Amiodarone increases exposure of direct oral anticoagulants (DOACs). We aimed to analyze the effects of concurrent amiodarone use on DOAC concentrations and clinical outcomes.
Shin-Yi Lin, Yen-Bin Liu, Li-Ting Ho, Yu-Fong Peng, Ching-Hua Kuo, Sung-Chun Tang, Chih-Fen Huang, Jiann-Shing Jeng   +7 more
doaj   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Amiodarone-induced reversible and irreversible hepatotoxicity: two case reports

Journal of Medical Case Reports, 2018
Background Amiodarone is a highly effective treatment for supraventricular and ventricular tachyarrhythmia; however, it could be associated with several serious adverse effects, including liver injury.
Toyonobu Tsuda, Hayato Tada, Yoshihiro Tanaka, Naoto Nishida, Taiji Yoshida, Takeshi Sawada, Kenji Sakata, Kenshi Hayashi, Masa-aki Kawashiri, Takeru Oyama, Motoko Sasaki, Nozomu Kurose, Masakazu Yamagishi   +12 more
doaj   +1 more source