Results 21 to 30 of about 33,645 (162)
Background Atrial and ventricular arrhythmias are commonly encountered in patients with advanced heart failure, with amiodarone being the most commonly used antiarrhythmic drug in continuous‐flow left ventricular assist device (CF‐LVAD) recipients.
Rakesh Gopinathannair +13 more
doaj +1 more source
Background: Intravenous amiodarone is considered to be the first-line drug for the treatment of ventricular tachycardia or fibrillation. However, in Japan, nifekalant had been used before the introduction of amiodarone; therefore, most clinical studies ...
Mari Amino, MD, PhD +8 more
doaj +1 more source
Amiodarone-Induced Acute Liver Injury
Amiodarone is a lipophilic structure with a half-life of 25–100 days. Long-term oral amiodarone is associated with photosensitivity, thyroid dysfunction, and pulmonary and hepatic toxicity.
Rajesh Essrani +7 more
doaj +1 more source
Cardiomyocyte-Targeting Peptide to Deliver Amiodarone
Background: Amiodarone is underutilized due to significant off-target toxicities. We hypothesized that targeted delivery to the heart would lead to the lowering of the dose by utilizing a cardiomyocyte-targeting peptide (CTP), a cell-penetrating peptide ...
Maliha Zahid +7 more
doaj +1 more source
NF-κB inhibitor or NAC attenuates amiodarone-induced injury of human lung epithelial cell line BEAS-2B [PDF]
Objective To investigate the mechanism of reactive oxygen species (ROS) and pyroptosis in amiodarone-induced lung epithelial cell injury. Methods The viability of cells treated with amiodarone, amiodarone+N-acetylcysteine(ROS inhibitor,NAC) and ...
JI Zezhao, ZHANG Qi, Abuduxukuer·ABULIMITI
doaj +1 more source
Amiodarone is a highly effective antiarrhythmic drug, but can have serious adverse effects, particularly in older patients. If possible it should not be used purely for controlling the heart rate If a prescription for amiodarone is contemplated, particularly for an older patient, consult a cardiologist.
Srinivasan, Meera +3 more
openaire +2 more sources
Management of amiodarone-related thyroid problems
Amiodarone is a highly effective and well-established antiarrrhythmic drug. It can be used to treat supraventricular and ventricular tachyarrhythmias and has the added advantage of being well tolerated in patients with impaired left ventricular systolic ...
Shashithej K. Narayana +2 more
doaj +1 more source
Amiodarone, a benzofuranic iodine-rich antiarrhythmic drug, causes thyroid dysfunction in 15-20% of cases. Amiodarone can cause both hypothyroidism (AIH, amiodarone-induced hypothyroidism) and thyrotoxicosis (AIT, amiodarone-induced thyrotoxicosis). AIH is treated by L-thyroxin replacement and does not need amiodarone discontinuation.
Agata Jabrocka-Hybel +7 more
openaire +3 more sources
Local Use of Hydrogel with Amiodarone in Cardiac Surgery: Experiment and Translation to the Clinic
The objective of this study was to study the use of the hydrogel biopolymer based on sodium alginate (“Colegel”) with a drug substance—amiodarone—for the prevention of postoperative atrial fibrillation (POAF) in cardiac surgery.
Vladimir Shvartz +6 more
doaj +1 more source
Use of haloperidol in amiodarone induced delirium
Amiodarone, a versatile Class III antiarrhythmic drug, is considered one of the most effective agents in counteracting supraventricular and ventricular tachyarrhythmia.
Rachit Sharma +2 more
doaj +1 more source

