Results 131 to 140 of about 28,292 (266)

New-Onset Arrhythmias in Advanced Lung Cancer Patients Undergoing Anlotinib Treatment. [PDF]

Cardiovasc Toxicol
Shang C, Wang H, Chen J, Cao S, Sun Y, Sheng Z, Chu T, Zhao L.   +7 more
europepmc   +1 more source

[Propafenone as an anti-arrhythmia agent].

Wiadomosci lekarskie (Warsaw, Poland : 1960), 1987
A, Tomaszewski, A, Kleinrok, M, Markiewicz   +2 more
openaire   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

Arrhythmogenic Implications of Inflammatory Bowel Disease: Its Mechanisms and Treatment Effects. [PDF]

Cureus
Almasri ES, Siddiqui TW, Almasri RM, Abdulla G, Benoj AA, Pradeep G, Abu-Sa'da MO, Alaboud A, Fatayerji RN, Siddiqui RW.   +9 more
europepmc   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Cardiovascular adverse effects of common non-oncologic medications: from mechanisms to clinical management. [PDF]

Eur Heart J Cardiovasc Pharmacother
Bahit MC, Agudo-Quilez P, Zamorano J, Gibson CM.   +3 more
europepmc   +1 more source

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

The Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim, Hieu Trong Huynh, Phuong Kim Luong, Tran Nguyet Trinh, Yixuan Wu, Eleonora Grandi, Sun‐Hee Woo   +6 more
wiley   +1 more source

Frequently Underappreciated Considerations in Anti-arrhythmic Drug Therapy. [PDF]

J Innov Card Rhythm Manag
Reiffel JA.
europepmc   +1 more source

Ro5‐4864, a ligand of the mitochondrial translocator protein, protects against heart failure in mice via regulation of the p62‐Keap1‐Nrf2 axis

The Journal of Physiology, EarlyView.
Abstract figure legend Graphical abstract of the proposed Ro5‐4864 mechanism of action via p62‐Keap1‐Nrf2 axis in heart failure. TSPO, the 18‐kDa mitochondrial translocator protein of the outer mitochondrial membrane, can directly interact with p62 (also known as SQSTM1), which is crucial for the degradation of damaged mitochondria by autophagy ...
Daphne A. Diloretto, Phung N. Thai, Gabriela Grigorean, Veneese J. Brown, Tjien Dwyer, Nipavan Chiamvimonvat, Elena N. Dedkova, Saul Schaefer   +7 more
wiley   +1 more source

Patients Experiencing Unsuccessful Defibrillation From Implantable Cardiac Devices Remain at Elevated Risk Despite Procedural Management. [PDF]

J Cardiovasc Electrophysiol
Christian-Miller N, Shah M, Arps K, Deshmukh A, Liang J, Cunnane R, Jongnarangsin K, Pelosi F, Oral H, Ghannam M.   +9 more
europepmc   +1 more source