Results 161 to 170 of about 326,497 (313)

Results from a national observational survey of UK cardiologists on antibiotic envelope use during cardiac electronic device implantation. [PDF]

BMJ Open
Ravendren A, Kaza N, Naraen A, Geneste A, Zuhair M, Porter B, Shun-Shin MJ, Arnold A, Whinnett Z, Keene D.   +9 more
europepmc   +1 more source

Metformin‐based oral antihyperglycemic combination therapy and risk of dementia in patients with newly diagnosed type 2 diabetes: A population‐based study

Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract INTRODUCTION This study examined the association between metformin‐based oral antihyperglycemic combination therapy and the risk of developing dementia in patients with newly diagnosed type 2 diabetes mellitus (T2DM). METHODS We conducted a retrospective cohort study using data from a random sample of 2,000,000 individuals in Taiwan's National
Tsung‐Cheng Hsieh, Hsiang‐Hao Chen, Wei‐Chuan Chang, Chen‐Pei Ho   +3 more
wiley   +1 more source

Evaluating the Lidocaine's Initial Dosing in Patients With Ventricular Arrhythmias and Heart Failure Admitted in Intensive Care Units. [PDF]

Clin Cardiol
Kido K.
europepmc   +1 more source

Cardiovascular contributions to dementia: Examining sex differences and female‐specific factors

Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract Growing evidence underscores the importance of cardiovascular contributions to Alzheimer's disease and related dementias (AD/ADRD). While sex differences in cardiovascular disease (CVD) risk factors and outcomes are well established, the question of whether vascular contributions to AD/ADRD vary by sex has only recently garnered attention.
Madeline Wood Alexander, Jane Paterson, Zoe Arvanitakis, Sandra E. Black, Kaitlin B. Casaletto, Marie K. Christakis, Gillian Einstein, Liisa A. M. Galea, Leila Harwood, Amy Kirkham, Sara Mitchell, Judy Pa, Lucas Perri, Tallinn F. L. Splinter, Walter Swardfager, Anna M. VandeBunte, Jennifer S. Rabin   +16 more
wiley   +1 more source

Empagliflozin attenuates ventricular fibrillation postmyocardial infarction associated with reduced transforming growth factor-<b>β</b>1/Smad3 signaling and miR-181a expression. [PDF]

J Int Med Res
Shen J, Huang M, Ye Z, Jing Y, Yuan Z, Xiang Z, Ding M, Li T, Ye Q.   +8 more
europepmc   +1 more source

Real‐World Treatment Patterns and Outcomes in Patients With Relapsed/Refractory Multiple Myeloma and 1–3 Prior Lines of Therapy: Optum Database

Cancer Medicine, Volume 14, Issue 15, August 2025.
ABSTRACT Background Early (often continuous) treatment of multiple myeloma (MM) with lenalidomide has become common practice, leading to an increase in lenalidomide‐refractory disease. Methods We report real‐world treatment patterns, health care resource utilization (HCRU), and outcomes for patients with lenalidomide‐refractory MM using data from Optum
Binod Dhakal, Hermann Einsele, Jordan M. Schecter, William Deraedt, Nikoletta Lendvai, Ana Slaughter, Carolina Lonardi, Sandhya Nair, Nirosha Elsem Varghese, Jianming He, Akshay Kharat, Seina Lee, Patricia Cost, Ravi Potluri, Mythili Koneru, Nitin Patel, Erika Florendo, Paula Rodriguez‐Otero, Kwee Yong   +18 more
wiley   +1 more source

Prognostic relevance of arrhythmic and QTc burden in takotsubo cardiomyopathy: A systematic review and meta-analysis. [PDF]

J Arrhythm
Hanmandlu A, Varun Inampudi J, Hamza M, Upreti P, Bahar AR, Basit J, Neppala S, Chigurupati HD, Goru R, Alraies MC.   +9 more
europepmc   +1 more source

ECMO‐Assisted Da Vinci Robotic Surgery for Pheochromocytoma‐Induced Acute Catecholamine Cardiomyopathy: A Case Report

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Pheochromocytoma, an uncommon neuroendocrine neoplasm, has the potential to precipitate acute catecholamine cardiomyopathy (ACIC), a perilous condition characterized by cardiogenic shock and the failure of multiple organ systems. The significance of early diagnosis and the implementation of a multidisciplinary approach are paramount for ...
Qi Wang, Jiayan Xin, Xiaoqiong Cui, Liya Hu, Meng Ning, Wenqing Gao, Yingwu Liu   +6 more
wiley   +1 more source

Gene Therapy for Cardiac Arrhythmias: Mechanisms, Modalities and Therapeutic Applications. [PDF]

Med Sci (Basel)
Karakasis P, Theofilis P, Vlachakis PK, Milaras N, Kalinderi K, Patoulias D, Antoniadis AP, Fragakis N.   +7 more
europepmc   +1 more source

Reversing cardiac hypertrophy and heart failure using a cardiac targeting peptide linked to miRNA106a

Clinical and Translational Medicine, Volume 15, Issue 8, August 2025.
Molecular pathways involved with heart failure are complex. We generated a cardiac targeting peptide (CTP) linked to miRNA106a, a first‐of‐a‐kind cardiac‐specific drug, to downregulate genes involved in hypertrophy and inflammation, specifically PLCβ1 and CamKIIδ pathways. CTP delivers miRNA106a cargo specifically to cardiomyocytes in vitro and in vivo.
Ming Lu, Siqi Cai, Kyle Korolowicz, Claire Deng, Kaan Taskintuna, Gerard Ahern, Raymond B. Yurko, Kazi R. Islam, Bryn Schoonover, Jack B. Lopuszynski, Hongkun Wang, Maliha Zahid, G. Ian Gallicano   +12 more
wiley   +1 more source