Results 191 to 200 of about 48,847 (353)

Role of implantable loop recorders in optimizing care for patients during and after left ventricular assist device support: a single centre experience. [PDF]

BMC Cardiovasc Disord
Emam AY, El Husseny MWA, Ellithy A, Fawzy N, Elghazoly A, Ahmed E, Selwanos PP, Kamel O.   +7 more
europepmc   +1 more source

Life‐Threatening Agranulocytosis Induced by Sinomenine Hydrochloride in Chronic Kidney Disease: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Sinomenine, derived from Sinomenium acutum, is widely used in inflammatory diseases. However, its risk of inducing agranulocytosis is not widely appreciated. We report a life‐threatening case in a 40‐year‐old woman with chronic kidney disease (CKD; baseline estimated glomerular filtration rate [eGFR] as low as 36 mL/min/1.73 m2) who developed ...
Ping Xin, Ruoyan Liu, Yu Zhang, Bin Fu
wiley   +1 more source

Ranolazine in patients with chronic coronary syndromes: real-world data provide new evidence on the antiarrhythmic properties of the drug. [PDF]

Eur Heart J Cardiovasc Pharmacother
Fumagalli S, Dovizio M, Mazzoni S, Degli Esposti L, Santamaria E, Spanalatte G, Fumagalli C, Cagnoni C, Tariello A, Cerbai E, Marchionni N.   +10 more
europepmc   +1 more source

Synthesis and In Vitro Activity of Hypofuran B and Analogs Against Plasmodium Falciparum and Trypanosoma Cruzi

ChemMedChem, Volume 21, Issue 1, January 2026.
Hypofuran B, drynaran, and a series of analogs are obtined by crossed aldol condensation from furfural dereivatives. Compunds are tested for in vitro activity agaisnt Trypanosoma cruzi and Plasmodium falciparum. Best results are obtained Against P. falciparum, with IC50 values ranging from 5,35 to 10,35 µg mL−1.
Cristiane Aparecida Franco, Jodieh Oliveira Santana Varejão, Isabela Penna Ceravolo, Victória Miranda Machado, Antoniana Ursine Krettli, Daniela de Melo Resende, Silvane Maria Fonseca Murta, Felipe Terra Martins, Eduardo Jorge Pilau, Vinícius Ribeiro Montes, Markus Kohlhoff, Eduardo V. V. Varejão   +11 more
wiley   +1 more source

A Retrospective Long-Term Follow-Up of the Randomized Study: Total Endoscopic Ablation of Patients With Long-Standing Persistent Atrial Fibrillation. [PDF]

Interdiscip Cardiovasc Thorac Surg
Wickbom A, Fengsrud E, Ahlsson A.
europepmc   +1 more source

Ryanodine‐1‐Calstabin Complex Stabilizers in Antidoping Research: Synthesis, Metabolism, and Characterization

ChemPlusChem, Volume 91, Issue 1, January 2026.
RYR‐stabilizers such as S107, JTV‐519, ARM 036, and ARM 210 are emerging doping‐relevant compounds due to their performance‐enhancing effects on leaky skeletal muscle Ca2+ channels. To support proactive antidoping efforts, all four compounds were synthesized and their in vitro metabolism was systematically investigated.
Tristan Möller, Thomas Piper, Mario Thevis   +2 more
wiley   +1 more source

Impact of Antihypertensive Treatment on Outcomes of Adjuvant Bevacizumab for Ovarian Cancer (IATRO), Results from a Nationwide Emulated Clinical Trial

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 198-207, January 2026.
Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum, Élise Dumas, Joe‐Elie Salem, Stéphane Ederhy, Anne‐Sophie Hamy, Lise Lecointre, Enora Laas, Fabien Reyal, Fabrice Lecuru, Cherif Akladios, Paul Gougis   +10 more
wiley   +1 more source

Tirzepatide and Cardiovascular Outcomes: A Narrative Review of Mechanisms, Efficacy and Implications for Heart Failure Management

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Integrated framework for tirzepatide in HFpEF management. Through metabolic, haemodynamic, structural and anti‐inflammatory pathways, tirzepatide modifies the disease trajectory of HFpEF, leading to improvements in symptoms, functional capacity and reduction in HF events.
Hamza A. Abdul‐Hafez, Ameer Awashra, Sosana Bdir, Sarah Saife, Qasem Salah, Mohammed Barbarawi, Thabet Swaileh, Ahmed Emara, Mohamed S. Elgendy, Abdalhakim Shubietah   +9 more
wiley   +1 more source

Cardiac sarcoidosis: The role of steroid therapy in managing myocardial inflammation and arrhythmic risks. [PDF]

World J Cardiol
Bhimani S, Rojulpote C, Deshpande Y, Maligireddy AR.   +3 more
europepmc   +1 more source

Association of the Composite Dietary Antioxidant Index with All‐Cause, Cancer, and Cardiovascular Mortality: A Prospective Cohort Study

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
This prospective cohort study investigates the relationship between the Composite Dietary Antioxidant Index (CDAI) and cause‐specific as well as all‐cause mortality. Higher CDAI levels were significantly associated with reduced cardiovascular and cancer mortality, though associations weakened after full adjustment.
Niloufar Abdollahpour, Nadia Homayounfar, Farima Farsi, Sara Saffar Soflaei, Mohammad Kalate Rahmani, Mina Mousavi, Mohsen Mouhebati, Habibollah Esmaily, Najmeh Seifi, Majid Ghayour‐Mobarhan   +9 more
wiley   +1 more source