Results 91 to 100 of about 3,604,842 (297)

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Design, Development and Evaluation of Extended Release Tablets of Anti-asthmatic Agents using various Polymers

International Journal of Research and Development in Pharmacy & Life Sciences, 2018
The aim of this investigation was to define and assess Salbutamol sulphate and Theophylline framework tablets, prolonged discharge dosage form, for the treatment of Chronic Obstructive Pulmonary Disease (COPD). Powder blends of the drugs (Salbutamol sulphate and Theophylline) and polymers (HPMC K100M and Xanthan Gum) were evaluated for loose bulk ...
Anil Kumar, Naveen Goyal
openaire   +1 more source

Liposomes prolong the therapeutic effect of anti-asthmatic medication via pulmonary delivery

, 2012
Xiaoyu Chen, Wenhua Huang, Blenda Chi Kwan Wong, Linlin Yin, Yuen Fan Wong, Min Xu, Zhijun YangSchool of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong KongPurpose: The main objective of this study was to develop a novel aerosolized ...
Yang Z, Xu M, Huang W, Kwan Wong BC, Wong YF, Chen X, Yin L   +6 more
core  

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

iNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang, Yajuan Wu, Huayang Sheng, Shouhong Jiang, Jinping Cheng, Ye Kuang, Miao Liu, Lei Feng, Yanan Sun, Jinzhi Duan   +9 more
wiley   +1 more source

Safety and Efficacy of Mepolizumab during Pregnancy and Postpartum

Acta Médica Portuguesa
n/a.
Joana Marques Simões, Daniela Vidal, Daniel Laorden, Magdalena Lluch-Bernal, Javier Domínguez-Ortega   +4 more
doaj   +1 more source

Successful treatment with mepolizumab in a case of allergic bronchopulmonary aspergillosis complicated with nontuberculous mycobacterial infection

Respiratory Medicine Case Reports, 2019
Allergic bronchopulmonary aspergillosis (ABPA) is a complex hypersensitivity reaction that is associated with an allergic immunological response to Aspergillus species via Th2-related inflammation.
Hironobu Tsubouchi, Shinpei Tsuchida, Shigehisa Yanagi, Takafumi Shigekusa, Mariko Miura, Kenjiro Sakaguchi, Nobuhiro Matsumoto, Masamitsu Nakazato   +7 more
doaj   +1 more source

FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS OF ANTI-ASTHMATIC AGENT USING VARIOUS POLYMERS

Journal of Drug Delivery and Therapeutics, 2013
The objective of the present study was to develop matrix tablets of salbutmol sulphate sustained release dosage form, for the treatment of Chronic Obstructive Pulmonary Disease (COPD). Compatibility study was performed through Fourier Transformer Infrared spectroscopy revealed that there no interaction between drug and polymers.
Prakash B Mote, Pavan K. Rawat K Rawat, Shailendra K Singh, Nityanand S Zadbuke, Amarjit A Salunke, Vivek B Rajendra   +5 more
openaire   +2 more sources

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Maternal asthma during pregnancy and the likelihood of neurodevelopmental disorders in offspring

Acta Obstetricia et Gynecologica Scandinavica
Introduction Asthma is the most common chronic disease during pregnancy. Maternal asthma has been associated with a multitude of unwanted pregnancy outcomes, in some studies also with neurodevelopmental disorders.
Mari Kemppainen, Mika Gissler, Turkka Kirjavainen   +2 more
doaj   +1 more source

In vitro plant regeneration and bioactive metabolite production of endangered medicinal plant Fritillaria cirrhosa

Current Plant Biology
The bulb of Fritillaria cirrhosa D. Don is widely used for the anti-asthmatic, anti-tussive, and anti-cancer agents, etc., while the yield is limited by an endangered status, a long juvenile phase, and restricted growth habitat.
Zhen Zhang, Chengyuan Xing, Hongyan Su, Jianghang Wang, Yaodong Qi, Mengfei Li   +5 more
doaj   +1 more source