Results 121 to 130 of about 32,098 (325)

Adenosine signaling in airways: Toward a promising antiasthmatic approach [PDF]

open access: yes, 2013
Adenosine participates to asthma physiopathology by signaling through more than just one receptor subtype. Defining the role of each receptor is complicated by evidence that often results obtained on rodents do not coincide with human studies, but what ...
CICALA, CARLA, IALENTI, ARMANDO
core   +1 more source

Serious Infections in Offspring Exposed to Tumour Necrosis Factor Inhibitors During Pregnancy: Comparison of Timing During Pregnancy and Placental Transfer Ability

open access: yesArthritis &Rheumatology, Accepted Article.
Objective We evaluated serious infection risk in offspring exposed to tumour necrosis factor inhibitors (TNFi) in utero, separated by TNFi timing and placental transfer ability. Methods Using MarketScan (2011‐2021), we identified offspring born to mothers with chronic inflammatory diseases.
Leah K. Flatman   +6 more
wiley   +1 more source

Synthesis and in vitro evaluation of anti-inflammatory, antioxidant, and anti-fibrotic effects of new 8-aminopurine-2,6-dione-based phosphodiesterase inhibitors as promising anti-asthmatic agents

open access: hybrid, 2021
Katarzyna Wójcik‐Pszczoła   +12 more
openalex   +1 more source

A Novel A1 Adenosine Receptor Antagonist, L-97-1 [3-[2-(4-Aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], Reduces Allergic Responses to House Dust Mite in an Allergic Rabbit Model of Asthma [PDF]

open access: yes, 2005
Adenosine, an important signaling molecule in asthma, produces bronchoconstriction in asthmatics. Adenosine produces bronchoconstriction in allergic rabbits, primates, and humans by activating A1 adenosine receptors (ARs).
Batra, V. K.   +5 more
core   +1 more source

Prescribing competence: The pros and cons of different methods for assessment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman   +3 more
wiley   +1 more source

The integration of the British Pharmacological Society's prescription safety assessment into the WHO 6‐step model of rational pharmacotherapy in a Turkish medical school

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims At Koç University School of Medicine, a one‐week rational pharmacotherapy (RPHM) programme, modelled after WHO 6‐step, has been introduced in the fourth‐year curriculum to improve prescription skills. For efficient problem‐based learning (PBL) sessions on a prespecified topic, students need to brush up on basic pharmacology knowledge, so we ...
Sinem Ezgi Gülmez   +2 more
wiley   +1 more source

Improvement of Asthma Management in Actual Practice Consistent with Prevalence of Anti-inflammatory Agents—Based on Questionnaire Surveys in Niigata Prefecture, Japan from 1998 to 2002—

open access: yesAllergology International, 2005
Background: Because bronchial inflammation was recognized as a basic component of bronchial asthma, the strategy for asthma management has changed in the last two decades.
Takashi Hasegawa   +8 more
doaj   +1 more source

The reciprocal influences of asthma and pregnancy in Maltese women [PDF]

open access: yes, 1992
Asthma has been reported to complicate 1 % of pregnancies and increase the likelihood of prematurity and low birth weight (Cordon et aI, 1970). Pregnancy itself may alter the course of asthma.
Zammit, Danielle
core  

Machine learning methods for predicting adverse drug events: A systematic review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo   +8 more
wiley   +1 more source

Ensayo clínico con polvo de Musa paradisiaca en el tratamiento intercrisis del asma bronquial en adultos

open access: yesRevista Cubana de Investigaciones Biomédicas, 1998
Se realizó un ensayo clínico controlado, paralelo y a doble ciegas para evaluar la utilidad de las cápsulas de polvo de Musa paradisiaca en el tratamiento intercrisis del asma bronquial.
Alicia Zapata Martínez   +3 more
doaj  

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