Results 121 to 130 of about 32,319 (328)

Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. [PDF]

open access: yes, 1994
Eosinophil accumulation is a prominent feature of allergic inflammatory reactions, such as those occurring in the lung of the allergic asthmatic, but the endogenous chemoattractants involved have not been identified.
Collins, PD   +8 more
core   +1 more source

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy   +4 more
wiley   +1 more source

The reciprocal influences of asthma and pregnancy in Maltese women [PDF]

open access: yes, 1992
Asthma has been reported to complicate 1 % of pregnancies and increase the likelihood of prematurity and low birth weight (Cordon et aI, 1970). Pregnancy itself may alter the course of asthma.
Zammit, Danielle
core  

What have transgenic and knockout animals taught us about respiratory disease? [PDF]

open access: yes, 2000
Over the past decade there has been a significant shift to the use of murine models for investigations into the molecular basis of respiratory diseases, including asthma and chronic obstructive pulmonary disease.
AM Krieg   +27 more
core   +2 more sources

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

open access: yesChemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

Synthesis and in vitro evaluation of anti-inflammatory, antioxidant, and anti-fibrotic effects of new 8-aminopurine-2,6-dione-based phosphodiesterase inhibitors as promising anti-asthmatic agents

open access: hybrid, 2021
Katarzyna Wójcik‐Pszczoła   +12 more
openalex   +1 more source

Evaluation of the Therapeutic Potential of Bioactive Materials Based on a Complex of Oxidovanadium(IV) and Exopolysaccharide Levan in a Model of Insulin Resistance in Mice

open access: yesChemMedChem, EarlyView.
A low‐toxicity bioactive composition of oxidovanadium(IV) and exopolysaccharide levan is synthesized, characterized, and shown to reduce hyperglycemia, hypertriglyceridemia, and TyG index in a mice model of dexamethasone‐induced insulin resistance. Bioactive compositions containing vanadium complexes have been a viable strategy for constructing more ...
Amanda K. J. P. F. da Silva   +8 more
wiley   +1 more source

Improvement of Asthma Management in Actual Practice Consistent with Prevalence of Anti-inflammatory Agents—Based on Questionnaire Surveys in Niigata Prefecture, Japan from 1998 to 2002—

open access: yesAllergology International, 2005
Background: Because bronchial inflammation was recognized as a basic component of bronchial asthma, the strategy for asthma management has changed in the last two decades.
Takashi Hasegawa   +8 more
doaj   +1 more source

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali   +4 more
wiley   +1 more source

Ensayo clínico con polvo de Musa paradisiaca en el tratamiento intercrisis del asma bronquial en adultos

open access: yesRevista Cubana de Investigaciones Biomédicas, 1998
Se realizó un ensayo clínico controlado, paralelo y a doble ciegas para evaluar la utilidad de las cápsulas de polvo de Musa paradisiaca en el tratamiento intercrisis del asma bronquial.
Alicia Zapata Martínez   +3 more
doaj  

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