Results 121 to 130 of about 3,604,842 (297)
Mass Spectrometry Reviews, EarlyView.ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley +1 more source
The Incidence of Sensorineural Hearing Loss Diagnoses in People with and without Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.Abstract Background Parkinson's disease (PD) and sensorineural hearing loss (SNHL) are both prevalent conditions among older adults. Although increasing number of studies have investigated SNHL as a risk factor for PD, it is not well known how diagnosed PD affects the likelihood of SNHL diagnosis.
Kaisa Hokkinen +4 more
wiley +1 more source
Med Research, EarlyView.This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng +14 more
wiley +1 more source
Assessment of βAR desensitization in non-asthmatic ASM and asthmatic ASM cells.
, 2015 a, To determine whether βAR are differentially phosphorylated in non-asthmatic ASM and asthmatic ASM cells, the cells were plated on cover slips and β2AR phosphorylation was visualized by confocal microscopy using anti-phospho-S-355/356 β2AR antibody ...
Sathyamangla V. Naga Prasad (747260) +7 more
core +1 more source
The innate anti-viral effects of Azithromycin and other novel macrolides
, 2015 Asthma exacerbations are highly associated with respiratory viral infections, particularly rhinovirus (RV) infection. Currently, standard asthma medication does not include anti-viral agents despite the role viruses play.
Porter, James Daniel
core +1 more source
Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting
PM&R, EarlyView.Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy +3 more
wiley +1 more source
Advancing pharmacometrics in Africa—Transition from capacity development toward job creation
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai +10 more
wiley +1 more source
The Role of AMPK in Diabetic Cardiomyopathy and Related Intervention Strategies
Shengwu huaxue yu shengwu wuli jinzhanDiabetic cardiomyopathy is a distinct form of cardiomyopathy that can lead to heart failure, arrhythmias, cardiogenic shock, and sudden death. It has become a major cause of mortality in diabetic patients.
LIAO Fang-Lian +4 more
doaj +1 more source
Phytotherapy Research, EarlyView.Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko +3 more
wiley +1 more source