Targeting carboxypeptidase A/B activity with the phosphinic inhibitor C28 reduces the asthmatic response in a mouse model of house dust mite-induced asthma. [PDF]
Allam VSRR+10 more
europepmc +1 more source
The Concentration of Leukocyte Elastase-alpha1-Proteinase Inhibitor Complex in Bronchoalveolar Lavage Fluid from Healthy Human Subjects [PDF]
Bieth, J. G.+4 more
core +1 more source
Neutrophil activation in beta‐lactams (BL) immediate hypersensitivity reactions (IHR). Factor component analysis of IHR biomarkers suggests an IgG‐mediated mechanism. We propose Neutrophil Elastase as a biomarker of neutrophil activation in BL IHR. ABSTRACT Background Beta‐lactams (BLs) are the predominant cause of immediate allergic reactions to drugs.
Adrienne Astrid Gallizzi+13 more
wiley +1 more source
Is There a Place for Cannabinoids in Asthma Treatment? [PDF]
Lewandowska AA+4 more
europepmc +1 more source
Almost one in five patients receiving biological treatment for severe asthma has comorbid atopic dermatitis. Patients with comorbid atopic dermatitis represent a distinct phenotype with early‐onset, allergic asthma. Comorbid atopic dermatitis impacts the choice of biologic for severe asthma in real‐life practice. IgE, immunoglobulin E; FeNO, fractional
Marianne Baastrup Soendergaard+14 more
wiley +1 more source
Mechanisms of <i>Aletris spicata</i> (Thunb.) Franch. Extract in Asthma Therapy: Oxidative Stress, Inflammation, and Gut Microbiota. [PDF]
Yang J+5 more
europepmc +1 more source
Budesonide 21-phosphate sodium salt for use as anti-inflammatory or anti-asthmatic agent.
Caliendo, Giuseppe+8 more
openaire +1 more source
Adverse Effects of Steroid Therapy in Sudden Sensorineural Hearing Loss: A Scoping Review
ABSTRACT Objective Sudden sensorineural hearing loss (SSNHL) is an otologic emergency and is treated with steroid therapy. Despite adverse events (AEs) associated with long‐term steroid use being well evidenced, there is sparsity of literature regarding the AEs of short‐course prescriptions in the SSNHL cohort, which limits the quality of patient ...
M. Achanta+5 more
wiley +1 more source
Reactive Oxygen Species in Asthma: Regulators of Macrophage Polarization and Therapeutic Implications: A Narrative Review. [PDF]
Liu Y, Zhang M, Wang T, Zhang J.
europepmc +1 more source
Summary Background and Objectives Systemic treatment of pregnant/breastfeeding atopic dermatitis (AD) patients is challenging due to limited safety data. We explored treatment practices with systemic agents, including the guideline‐recommended cyclosporine as the first systemic choice as well as emerging therapies, in this vulnerable population ...
Manuel P. Pereira+34 more
wiley +1 more source