Lysosomal acidity and cathepsin L activate eosinophils via ARG1-mediated arginine metabolism in allergic airway inflammation. [PDF]
Han Y +20 more
europepmc +1 more source
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh +7 more
wiley +1 more source
Hydrogen inhalation ameliorates lung inflammation in mice with asthma. [PDF]
Li H +7 more
europepmc +1 more source
Evaluation of association of blood and bronchoalveolar eosinophil numbers and serum total immunoglobulin E concentration with the expression of nonspecific airway reactivity in dogs [PDF]
Bice, D E +3 more
core
Integrating skin barrier measurements with omics and machine learning, we found that postbiotics and NAM regulate skin homeostasis through distinct, strain‐ and dose‐dependent mechanisms. Postbiotics primarily modulate skin barrier function by promoting keratinocyte differentiation and suppressing inflammation.
Yagiz Pat +21 more
wiley +1 more source
Predisposing Factors for Erosive Tooth Wear in Permanent Teeth Among Asthmatic Children and Adolescents. [PDF]
Samec TU, Jan J.
europepmc +1 more source
Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm +9 more
wiley +1 more source
Benzo[a]pyrene aggravated ovalbumin‑induced epithelial tight junction disruption via ROS driven‑NLRP3/Caspase‑1 signaling pathway in asthmatic mice. [PDF]
Xu Y +5 more
europepmc +1 more source
In this cross‐sectional study, pregnancy with subclinical hypothyroidism was associated with higher rates of severe maternal morbidity at delivery compared with overt hypothyroidism, including cardio‐pulmonary morbidity and eclampsia. This association was especially seen among younger age, Black individuals, prepregnant hypertension, and obesity ...
Laurel S. Aberle +10 more
wiley +1 more source
Naturally derived bioactive compounds as regulators of oxidative stress and inflammation in asthma. [PDF]
Lee J, Choi HK, Shin HS, Kim GD.
europepmc +1 more source

