Results 151 to 160 of about 375,460 (285)

Development of a Human 3D Immune‐Competent Neurovascular Model Enabling Time‐Resolved Monitoring of Neuroinflammatory Dynamics and Neuroimmune Interactions

Advanced Science, EarlyView.
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk, Jing Bai, Olurotimi A. Bolonduro, Andrew M. Silverman, Robert Madison Green, Jason H. Lasser, Paul W. Fleming, Lishomwa C. Ndhlovu, James F. Saunders, Dmitry Shvartsman   +9 more
wiley   +1 more source

Medicinal Plants: A Promising Therapeutic Approach for Addressing Antimicrobial Resistance. [PDF]

Int J Mol Sci
Zhou H, Du J, Jia M, Li Y, Zheng K.
europepmc   +1 more source

A Review On Lemongrass Oil Act As A Antifungal And Anti-Bacterial Agent

Lemongrass oil, derived from the Cymbopogon species, has been traditionally utilized for its diverse therapeutic properties. This review aims to consolidate and evaluate the scientific evidence regarding its antifungal and antibacterial activities. Lemongrass oil is rich in bioactive compounds, particularly citral, which is primarily responsible for ...
openaire   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

CDC\u2019S AR lab network uncovers antibiotic resistance & silent spread

AR LAB NETWORK1 in 4 bacteria tested was positive:\u2022 25% of the germs had special genes that allow them to spread their resistance to other germs. In response, many investigations were conducted and screening tests were performed.1 in 10 screening ...

core  

Old drugs, new weapons: current trends in repurposing therapies against antimicrobial resistance. [PDF]

J Pharm Pharm Sci
Srikanth G, Praveen Kumar N, Sridevi B, Borra PB, Thapar P, Wani A.   +5 more
europepmc   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

Characterization of green synthesized silver nanoparticles from Falconeria insignis Royle and its antimicrobial activity. [PDF]

PLoS One
Amithalal MS, Sumayli M, Abhilash ES, Hazzazi Y, Azizoglu U, Sajjad S, El-Shabasy A.   +6 more
europepmc   +1 more source

Dual‐Stage Microneedle Patch With Lipid Droplet‐Mediated ‘Capture‐Kill’ and Sustained Release for Enhanced Wound Healing

Advanced Science, EarlyView.
We report a lipid‐droplet‐engineered, gallium‐loaded sonodynamic therapeutic platform (LDTG) incorporated into a bilayer microneedle (MN) patch co‐delivering all‐trans retinoic acid (ATRA), termed LDTG A‐MNs, for synergistic antibacterial therapy and accelerated wound repair.
Peng Jiang, Meijun Jiang, Jiapeng Lei, Wen Zhang, Huiyuan Yang, Xueyang Wang, Siyu Zhang, Qiongfang Ruan, Shuhua Liu, Wei Li   +9 more
wiley   +1 more source

Natural Alkaloids as Antimicrobial Agents: Mechanisms, Potentials and Challenges. [PDF]

Molecules
Zhang XZ, Chen MX, Hou R, Wang WQ, He ZD, You JS, Song X.   +6 more
europepmc   +1 more source