Results 221 to 230 of about 356,287 (308)

Rupestonic Acid of Artemisia Rupestris L. Extract Treats Pulmonary Fibrosis in COPD by Targeting TGF‐β1

Advanced Science, EarlyView.
RA of EEAR inhibits TGF‐β1 ubiquitination and changes conformation by target binding TGF‐β1, regulating TGF‐β1/Smad2/3 signaling pathway. Thus it down‐regulated downstream protein expression, inhibited EMT and collagen deposition of ECM, in order to EEAR preventing PF in COPD.
Lingfeng Peng, Lulu Zhang, Yimeng Fan, Sijuan Huang, Qingyu Zhao, Chao Han, Zhihui Hao   +6 more
wiley   +1 more source

Antimicrobial and Anti-Infective Activity of Natural Products: Unveiling Mechanisms, Synergies, and Translational Applications. [PDF]

Antibiotics (Basel)
Fernandes ES, Campos CDL, Pereira-Filho JL, Monteiro CRAV, Monteiro-Neto V.   +4 more
europepmc   +1 more source

Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants

Advanced Science, EarlyView.
In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao, Yanbin Li, Shengqi Zhang, Yilin He, Zhiqi Liu, Juan Wang, Jingmin Hua, Jinyu Chen, Junru Zhong, Huan Zhong, Yiji Xia, Yong Cui, Liwen Jiang   +12 more
wiley   +1 more source

Engineering bacteriophages for gut health: precision antimicrobials and beyond. [PDF]

J Nanobiotechnology
Xu M, Chen S, Pei H, Hu L, Zhang Y.
europepmc   +1 more source

Chemoenzymatic Syntheses of Some Analogues of the Tricarbocyclic Core of the Anti-Bacterial Agent Platencin and the Biological Evaluation of Certain of their N-Arylpropionamide Derivatives*

, 2018
Rehmani N. Muhammad, Ee Ling Chang, Alistair G. Draffan, Anthony C. Willis, Paul D. Carr, Martin G. Banwell   +5 more
openalex   +2 more sources

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Addition of lactoferrin increases efficacy of three Kayviruses and limits the inflammatory response in pulmonary epithelial cells. [PDF]

Appl Microbiol Biotechnol
Kosznik-Kwaśnicka K, Stasiłojć G, Grzenkowicz M, Stasiłojć M, Necel A, Piechowicz L.   +5 more
europepmc   +1 more source

Anti-bacterial activity and anti-cancer agent studies of punica granatum peel-doped silver/calcium oxide nancomposites derived from camel bone [PDF]

Raiedhah A. Alsaiari, Esraa M. Musa, Fatima A. Al-Qadri, Mervate Mohamed Mohamed, Moustafa A. Rizk   +4 more
openalex   +1 more source

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

Advanced Science, EarlyView.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu, Dittman Lai‐Shun Chung, Larry Ka‐Yue Chow, Shuo Han, Wenkai Yi, Conor J. Cremin, Yingyin Liao, Pui Wang, Bobo Wing‐Yee Mok, Mingfang Ji, Jian Yan, Wei Dai, Honglin Chen   +12 more
wiley   +1 more source

Recent Developments on Coumarin Hybrids as Antimicrobial Agents. [PDF]

Antibiotics (Basel)
Peter S, Sibali LL.
europepmc   +1 more source