Results 201 to 210 of about 2,647,799 (293)

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

Anti-Biofilm Activity of (+)-Endo-Borneol Against <i>Streptococcus mutans</i>: Experimental Evaluation, Virulence Gene Expression Analysis, and Molecular Docking. [PDF]

open access: yesPlants (Basel)
Atazhanova G   +11 more
europepmc   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi   +4 more
wiley   +1 more source

Diverse Uses of Lantibiotics: Exploring New Approaches to Combat Antibiotic Resistance

open access: yesMedicine Advances, EarlyView.
This review illustrates lantibiotics as an alternative therapeutic approach to combat antibiotic resistance, highlighting their diverse sources, including plants, insects, animals, and microorganisms. It further emphasizes their broad therapeutic potential, including antibacterial, antifungal, antiparasitic, antiviral, and anticancer activities (GA ...
Gopalarethinam Janani   +5 more
wiley   +1 more source

Enhanced Recovery After Surgery in Simultaneous Pancreas–Kidney Transplantation: A Retrospective Cohort Analysis of Perioperative Outcomes

open access: yesOrgan Medicine, EarlyView.
ABSTRACT Background While simultaneous pancreas–kidney transplantation (SPK) is an established therapeutic intervention for patients with end‐stage renal disease and diabetes, it has been associated with prolonged recovery periods and high complication rates.
Rongxin Chen   +5 more
wiley   +1 more source

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