Results 221 to 230 of about 2,154,155 (297)

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Macrophage extracellular vesicles deliver Mef2d proteins to aggravate Bacteroides fragilis pathogenicity in type 2 diabetes arterial calcification

Interdisciplinary Medicine, EarlyView.
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen, Rong He, Jirong Luo, Zhengfeng Liang, Qunwen Pan, Shuangquan Liu, Jingsong Cao   +6 more
wiley   +1 more source

Anti-staphylococcal activity of the auranofin-analogous PEt₃AuCl: antibacterial, anti-biofilm and anti-virulence effect on clinically relevant staphylococci. [PDF]

Front Cell Infect Microbiol
Mazzantini D, Amato B, Zineddu S, de Azevedo-França JA, Maisetta G, Ghelardi E, Esin S, Messori L, Batoni G.   +8 more
europepmc   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

The anti-biofilm effect of ozonated water and super-oxidized water applied with different activation procedures against Enterococcus faecalis biofilm. [PDF]

BMC Oral Health
Albayrak F, Tunç T, Altunbaş D, Zan R, Ayhan M, Bal H.   +5 more
europepmc   +1 more source

A multicenter, controlled, randomized trial of home‐applied dual‐light photodynamic therapy in stage I to III periodontitis (LumoNorth2022 study)

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a widespread, chronic infection‐triggered inflammatory condition in which professional supportive periodontal care (SPC) and daily oral hygiene form the backbone to reduce the disease activity. Light‐based treatments have shown promising antibacterial effects, but their potential for routine home use has not been ...
Paula Tegelberg, Meeri Ojala, Merja Ylipalosaari, Jori Lindroth, Anna Maria Heikkinen, Hanna Lähteenmäki, Saila Pakarinen, Ismo T. Räisänen, Timo Sorsa, Tommi Pätilä   +9 more
wiley   +1 more source

Tunable anti-biofilm activity of Zn-doped CuO nanoparticles: structural, morphological, and biological insights against Gram-positive and Gram-negative bacteria. [PDF]

RSC Adv
Khlifi N, Mnif S, Zerrouki C, Guermazi H, Fourati N, Duponchel B, Aifa S, Guermazi S.   +7 more
europepmc   +1 more source

Betaine‐, xylitol‐, and extra virgin olive oil–based toothpaste modulates inflammation and oral nitric oxide pathway: Clinical trial in gingivitis

Journal of Periodontology, EarlyView.
Abstract Background Gingivitis is a prevalent and reversible inflammatory condition driven by microbial dysbiosis. Beyond plaque control, interest has grown in oral hygiene formulations capable of modulating inflammation while preserving key microbial functions. Extra virgin olive oil (EVOO), together with xylitol and betaine, has demonstrated clinical
Francisco Mesa, Alejandro Rodríguez‐Agurto, Marco Bonilla, Debora Rodríguez‐Vilaboa, Beatriz Rodríguez‐Vilaboa, Manuel Bravo   +5 more
wiley   +1 more source

Bacteriophage as an anti-biofilm agent against Pseudomonas aeruginosa from wound infection. [PDF]

PLoS One
Shrestha P, Tandukar S, Shrestha M, Shrestha S, Subedee A, Shakya J, Tuladhar R.   +6 more
europepmc   +1 more source

Impact of abrasive versus non‐abrasive cleaning on peri‐implantitis titanium release: A randomized clinical trial

Journal of Periodontology, EarlyView.
Abstract Background Surface decontamination is integral to peri‐implantitis treatment. However, abrasive mechanical methods can cause implant surface degradation with possible adverse biological effects. No human studies have examined whether these treatments cause titanium release or impair regenerative outcomes.
Georgios A. Kotsakis, Antonella Botto, Marzieh S. Jazaeri, Archontia Palaiologou, Eddie Lee, Diane M. Daubert   +5 more
wiley   +1 more source