Results 31 to 40 of about 1,620,652 (307)
Strategies for Interfering With Bacterial Early Stage Biofilms
Frontiers in Microbiology, 2021 Biofilm-related bacteria show high resistance to antimicrobial treatments, posing a remarkable challenge to human health. Given bacterial dormancy and high expression of efflux pumps, persistent infections caused by mature biofilms are not easy to treat,
Jingyuan Fu +12 more
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Norspermidine is not a self-produced trigger for biofilm disassembly [PDF]
, 2014 Formation of Bacillus subtilis biofilms, consisting of cells encapsulated within an extracellular matrix of exopolysaccharide and protein, requires the polyamine spermidine.
Stanley-Wall, Nicola R.; id_orcid +8 more
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Managing sticky situations – anti-biofilm agents [PDF]
GERMS, 2016 Biofilm-related infections are accountable for increasing morbidity and disability, particularly in an era when surgery has evolved to new heights and is able to repair or replace virtually any damaged component of the human body. Bacteria have recently been redefined as “intelligent” beings, able to communicate, coordinate, and store in their ...
openaire +2 more sources
Anti-Biofilm Activity of Cannabidiol against Candida albicans
, 2021 Candida albicans is a common fungal pathogen in humans. Biofilm formation is an important virulence factor of C. albicans infections. We investigated the ability of the plant-derived cannabidiol (CBD) to inhibit the formation and removal of fungal ...
Mark Feldman +3 more
core +1 more source
Lichen Polyphenolic Compounds for the Eradication of Candida albicans Biofilms
Frontiers in Cellular and Infection Microbiology, 2021 Lichens, due to their symbiotic nature (association between fungi and algae), constitute a chemical factory of original compounds. Polyphenolic compounds (depsides and depsidones) are the main constituents of lichens and are exclusively biosynthesized by
Marion Girardot +8 more
doaj +1 more source
Anti-biofilm activity of antibiotic-loaded Hylomate®
IJC Heart & Vasculature, 2021 Antibiotic envelopes are being developed for cardiac implantable electronic device (CIED) wrapping to reduce the risk of infections.Fifteen CIED infection-associated bacterial isolates of Staphylococcus aureus, Staphylococcus epidermidis and Cutibacterium acnes were used to assess in vitro biofilm formation on Hylomate® compared to titanium, silicone ...
Mariana Albano +4 more
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Characterization of Anti-Biofilm Peptide Activity: A Biophysical Approach [PDF]
Biophysical Journal, 2017 The increasing number of multidrug resistant bacteria to available antibiotics is a growing problem worldwide. One major strategy for resistance and an important reason for failure of therapy in the clinic is biofilm formation. To cope with unfavorable surroundings many bacteria live as biofilms, sessile micro-colonies adherent to surfaces that secrete
Segev Zarko Li av T +4 more
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Design and surface immobilization of short anti-biofilm peptides [PDF]
Acta Biomaterialia, 2017 Short antimicrobial peptides are essential to keep us healthy and their lasting potency can inspire the design of new types of antibiotics. This study reports the design of a family of eight-residue tryptophan-rich peptides (TetraF2W) obtained by converting the four phenylalanines in temporin-SHf to tryptophans. The temporin-SHf template was identified
Biswajit, Mishra +4 more
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The protein tyrosine kinases EpsB and PtkA differentially affect biofilm formation in Bacillus subtilis [PDF]
, 2014 The Gram-positive soil bacterium Bacillus subtilis is able to choose between motile and sessile lifestyles. The sessile way of life, also referred to as biofilm, depends on the formation of an extracellular polysaccharide matrix and some extracellular ...
Stanley-Wall, Nicola +6 more
core +1 more source
How well are we translating biofilm research from bench-side to bedside?
Biofilm, 2020 Biofilms are responsible for more than 80% of all chronic infections and represent an enormous medical challenge. In order to meet this challenge, translation research on anti-biofilm approaches is desperately needed.
Kendra P. Rumbaugh
doaj +1 more source