Results 171 to 180 of about 16,971 (214)

Endogenous retroelement activation is implicated in IFN-α production and anti-CCP autoantibody generation in early RA

open access: yes
Cooles FA   +12 more
europepmc   +1 more source

Anti-CCP biosensors in rheumatoid arthritis

Clinica Chimica Acta
Biosensors are unique analytical tools for the detection of biomarkers. Of these, autoantibodies against citrullinated proteins (ACPA) are useful for the differential diagnosis of rheumatoid arthritis (RA). The autoantibodies may be detected by immunoassay technology using synthetic cyclic citrullinated peptides (CCP), ie, anti-CCP.
Mohammad Johari-Ahar
exaly   +3 more sources

Anti-CCP antibodies in rheumatoid arthritis and psoriatic arthritis

Clinical Rheumatology, 2006
Our aim is to assess the prevalence and associated clinical features of anti-CCP (cyclic citrullinated peptide) antibodies for RF (rheumatoid factor)-positive and RF-negative rheumatoid arthritis (RA) and psoriatic arthritis (PsA). In a prospective, cross-sectional, multi-centre study, we determined the titres of anti-CCP antibodies in 208 RA patients (
Murat Inanç   +2 more
exaly   +5 more sources

Redefining the HLA and RA association: To be or not to be anti-CCP positive

Journal of Autoimmunity, 2005
Rheumatoid Arthritis (RA) is the most common chronic inflammatory joint disease. The overall prevalence is 1% and in people older than 60 it is more than 2%. RA has auto-immune features: auto-antibodies against the Fc part of IgG, so-called Rheumatoid Factor (RF) are found more often in RA patients and more recently RA-specific auto-antibodies directed
René R P, de Vries   +2 more
openaire   +2 more sources

High positivity of anti-CCP antibodies in patients with Down syndrome

Clinical Rheumatology, 2007
The aim of the present study was to evaluate the prevalence of anti-cyclic citrullinated peptide (CCP) antibodies in patients with Down's syndrome (DS) previously tested for IgM rheumatoid factor (RF) and to correlate the results with clinical findings.
Nisihara R   +2 more
exaly   +3 more sources

The association of anti-CCP antibodies with disease activity in rheumatoid arthritis [PDF]

open access: yesRheumatology International, 2008
Antibodies to citrullinated proteins have been described in patients with rheumatoid arthritis (RA) and these appear to be the most specific markers of the disease. Our objective was to determine the frequency of antibodies to cyclic citrullinated peptides (CCPs) in patients with RA and the association of anti-CCP antibodies with disease activity ...
Sibel Kul   +2 more
exaly   +3 more sources

The role of the shared epitope in arthralgia with anti-cyclic citrullinated peptide antibodies (anti-CCP), and its effect on anti-CCP levels

Annals of the Rheumatic Diseases, 2008
Patients presenting with both arthralgia and antibodies to cyclic citrullinated peptide (anti-CCP) have an increased risk of developing rheumatoid arthritis (RA). To further characterise this patient group and shed more light on its relationship with clinically manifest early arthritis and established RA, an immunogenetic and serological analysis was ...
Bos, W. H.   +11 more
openaire   +4 more sources

Clinical Utility of the Anti-CCP Assay: Experiences with 700 Patients

Annals of the New York Academy of Sciences, 2005
Abstract: Our objective was to determine the frequency of antibodies to cyclic citrullinated peptides (CCPs) in a series of patients with a variety of rheumatic diseases. Seven hundred consecutive serum samples from patients at an outpatient clinic were tested for the presence of rheumatoid factor (RF) and anti‐CCP.
Ulrich, Sauerland   +8 more
exaly   +3 more sources

The continuous measurement of anti-CCP-antibodies does not help to evaluate the disease activity in anti-CCP-antibody-positive patients with rheumatoid arthritis

Clinical Rheumatology, 2010
Anti-cyclic citrullinated peptide antibody (CCP-AB) are used for diagnosis of rheumatoid arthritis (RA). It is still unknown if the extent of CCP-AB levels is useful to assess the disease activity or the individual follow-up as an individual activity parameter. We investigated 40 patients with a known RA who were positive for CCP-AB.
Thoren, Landmann   +2 more
openaire   +2 more sources

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