Specificity of Anti-Citrullinated Protein Antibodies to Citrullinated α-Enolase Peptides as a Function of Epitope Structure and Composition [PDF]
Antibodies, 2021 Rheumatoid arthritis (RA) is an autoimmune disease affecting approximately 1–2% of the world population. In addition to the first discovered serologic markers for RA, the rheumatoid factors (RFs), anti-citrullinated protein antibodies (ACPAs) are even ...
Ilaria Fanelli +5 more
doaj +4 more sources
Specificity of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis [PDF]
Antibodies, 2019 Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology. The majority of individuals with RA are positive for the disease-specific anti-citrullinated protein antibodies (ACPAs).
Nicole H. Trier +5 more
doaj +4 more sources
Epitope Specificity of Anti-Citrullinated Protein Antibodies [PDF]
Antibodies, 2017 Anti-citrullinated protein antibodies are primarily associated with a progressive course in the autoimmune disease rheumatoid arthritis, a disease with a chronic and inflammatory nature.
Nicole H. Trier, Gunnar Houen
doaj +4 more sources
Anti-Carbamylated Fibrinogen Antibodies Might Be Associated With a Specific Rheumatoid Phenotype and Include a Subset Recognizing In Vivo Epitopes of Its γ Chain One of Which Is Not Cross Reactive With Anti-Citrullinated Protein Antibodies [PDF]
Frontiers in Immunology, 2021 To identify the targets recognized by anti-carbamylated protein antibodies (anti-CarP) in patients with early Rheumatoid Arthritis (RA), to study the cross-reactivity between anti-CarP and anti-citrullinated protein antibodies (ACPA) and to evaluate ...
Pauline Brevet +16 more
doaj +2 more sources
Relative efficiencies of peptidylarginine deiminase 2 and 4 in generating target sites for anti-citrullinated protein antibodies in fibrinogen, alpha-enolase and histone H3. [PDF]
PLoS ONE, 2018 OBJECTIVE:Peptidylarginine deiminase 2 (PAD2) and PAD4 are expressed in the synovium of rheumatoid arthritis (RA) patients and catalyze citrullination of arginine residues in proteins targeted by anti-citrullinated protein antibodies (ACPAs).
Dres Damgaard +5 more
doaj +2 more sources
From Rheumatoid Factor to Anti-Citrullinated Protein Antibodies and Anti-Carbamylated Protein Antibodies for Diagnosis and Prognosis Prediction in Patients with Rheumatoid Arthritis [PDF]
International Journal of Molecular Sciences, 2021 Shue-Fen Luo +2 more
exaly +2 more sources
Anti-Citrullinated Protein Antibodies in Patients with Rheumatoid Arthritis: Biological Effects and Mechanisms of Immunopathogenesis [PDF]
International Journal of Molecular Sciences, 2020 Huang-Yu Yang +2 more
exaly +2 more sources
Levels of Anti-Citrullinated Protein Antibodies and Rheumatoid Factor, Including IgA Isotypes, and Articular Manifestations in Ulcerative Colitis and Crohn’s Disease [PDF]
International Journal of Environmental Research and Public Health, 2020 Hilde Hop +2 more
exaly +2 more sources
Rheumatoid arthritis and the proinflammatory cytokine IL-17 [PDF]
Folia Medica, 2023 Introduction: Rheumatoid arthritis (RA) is the most common inflammatory joint disease. Various proinflammatory cytokines are involved in the pathogenesis of this chronic disorder.
Pavel Selimov +8 more
doaj +3 more sources
Rheumatology & Autoimmunity, 2022 Background A specific feature of the autoimmune response in rheumatoid arthritis (RA) is the presence of anti‐citrullinated protein antibodies (ACPAs) in patient sera. These antibodies can appear several years before disease onset and are involved in the
Xiaozhen Zhao +10 more
doaj +1 more source