Results 21 to 30 of about 5,314,909 (200)

Detection of salivary citrullinated cytokeratin 13 in healthy individuals and patients with rheumatoid arthritis by proteomics analysis.

PLoS ONE, 2022
The immune response to citrullinated peptides in the mucosa has been suggested to play an important role in the transition from pre-onset rheumatoid arthritis (RA) to clinically evident RA.
Takuya Yasuda, Koichiro Tahara, Tetsuji Sawada   +2 more
doaj   +2 more sources

Anti-carbamylated protein antibodies precede disease onset in monkeys with collagen-induced arthritis

Arthritis Research & Therapy, 2017
Background Rheumatoid factor (RF), anti-citrullinated protein antibodies (ACPA) and anti-carbamylated protein (anti-CarP) antibodies are rheumatoid arthritis (RA)-associated autoantibodies. Besides their presence in human serum, anti-CarP antibodies have
Marije K. Verheul, Michel P. M. Vierboom, Bert A. ’t Hart, Rene E. M. Toes, Leendert A. Trouw   +4 more
doaj   +1 more source

Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. [PDF]

JCI Insight, 2017
Art.e93688, 19 S.Today, it is known that autoimmune diseases start a long time before clinical symptoms appear. Anti-citrullinated protein antibodies (ACPAs) appear many years before the clinical onset of rheumatoid arthritis (RA).
Ge C, Tong D, Liang B, Lönnblom E, Schneider N, Hagert C, Viljanen J, Ayoglu B, Stawikowska R, Nilsson P, Fields GB, Skogh T, Kastbom A, Kihlberg J, Burkhardt H, Dobritzsch D, Holmdahl R.   +16 more
europepmc   +4 more sources

Neutrophil extracellular traps in inflammatory disorders [PDF]

, 2014
A novel feature of polymorphonuclear granulocyte (PMN) biology is their ability to generate neutrophil extracellular traps (NETs) via a distinct process of cell death termed NETosis.
Sur Chowdhury, Chanchal
core   +1 more source

Antineutrophil cytoplasmic autoantibodies and clinical activity in Cuban patients with rheumatoid arthritis

Revista Habanera de Ciencias Médicas, 2021
Introduction: Antibodies against neutrophil cytoplasm are normally detected in patients with vasculitis. Although these antibodies can be present in a wide number of diseases associated with inflammatory and autoimmune conditions such as rheumatoid ...
Goitybell Martínez Téllez, Barbara Torres Rives, Vicky Sánchez Rodríguez   +2 more
doaj  

Expression of recombinant multi-coloured fluorescent antibodies in gor ^-/trxB^- E. coli cytoplasm [PDF]

, 2011
Background Antibody-fluorophore conjugates are invaluable reagents used in contemporary molecular cell biology for imaging, cell sorting and tracking intracellular events.
Durvasula, Ravi V., Burchell, Joy Marilyn; id_orcid, Kang, Angray S., Anatoliy Markiv, Burchell, J, Durvasula, R.V., Beatson, R., Beatson Richard, Beatson, Richard; id_orcid, Kang Angray S, Markiv, A., Markiv Anatoliy, Kang, A.S., Richard Beatson, Burchell, J., Durvasula Ravi V, Ravi V Durvasula, Burchell, Joy; id_orcid, Durvasula, RV, Markiv, Anatoliy, Burchell Joy, Markiv, A, Angray S Kang, Beatson, Richard, Joy Burchell, Kang, AS, Beatson, R   +26 more
core   +1 more source

Clinical and etiological meaning of anti-carbamylated protein antibodies in rheumatoid arthritis

Immunological Medicine, 2019
Several autoantibodies against proteins with post-translational modifications have been detected in patients with rheumatoid arthritis (RA) and are called anti-modified protein antibodies (AMPAs).
Shuichiro Nakabo
doaj   +1 more source

A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity [PDF]

, 2007
Rheumatoid arthritis (RA) is a chronic inflammatory disease with a heritability of 60%. Genetic contributions to RA are made by multiple genes, but only a few gene associations have yet been confirmed.
Klareskog, Lars, Lars Klareskog, Rikard Holmdahl, Kallberg, H, Padyukov, L, Lars Alfredsson, Harald Burkhardt, Padyukov, Leonid, Olsson, Lina, Holmdahl, Rikard, Lina M Olsson, Burkhardt, H, Anna-Karin Lindqvist, Leonid Padyukov, Lindqvist, Anna-Karin,, Burkhardt, Harald, Klareskog, L, Lindqvist, Anna-Karin, Olsson, Lina M., Henrik Källberg, Olsson, Lina,, Källberg, Henrik, Alfredsson, Lars, Alfredsson, L, Lund University., Holmdahl, Rikard,   +25 more
core   +1 more source

Oligonucleotide-Peptide Conjugates: Solid-Phase Synthesis under Acidic Conditions and Use in ELISA Assays

Molecules, 2012
Here we used solid-phase methods to prepare oligonucleotides carrying fibrin/ filaggrin citrullinated peptides. Post-synthetic conjugation protocols were successfully applied for the synthesis of oligonucleotides carrying small peptides.
Ramon Eritja, Isabel Haro, Morteza Malakoutikhah, Maria José Gómara, Anna Aviñó   +4 more
doaj   +1 more source

Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin [PDF]

, 2004
Contains fulltext : 58941.pdf (Publisher’s version ) (Open Access)Antibodies directed to the Sa antigen are highly specific for rheumatoid arthritis ( RA) and can be detected in approximately 40% of RA sera.
Ménard, Henri, Vossenaar, Erik, Lora, Maximillian, Lora, M., Senshu, T., van Venrooij, Walther, Menard, H.A., Venrooij, W.J.W. van, Despres, N., Lapointe, Elvy, Lapointe, E., Heijden, A.G. van der, Vossenaar, E.R., Senshu, Tatsuo, van der Heijden, Annemarie, Després, Normand   +15 more
core   +2 more sources