Results 1 to 10 of about 241,882 (308)

Mutation Profile of HPV16 L1 and L2 Genes in Different Geographic Areas

Viruses, 2022
The causal relationship between HPV and cervical cancer in association with the high prevalence of high risk HPV genotypes led to the design of HPV vaccines based on the major capsid L1 protein.
Dimitris Tsakogiannis, Marios Nikolaidis, Flora Zagouri, Eleni Zografos, Christine Kottaridi, Zaharoula Kyriakopoulou, Lamprini Tzioga, Panayotis Markoulatos, Grigoris D. Amoutzias, Garyfalia Bletsa   +9 more
doaj   +1 more source

AI Aided Design of Epitope-Based Vaccine for the Induction of Cellular Immune Responses Against SARS-CoV-2

Frontiers in Genetics, 2021
The heavy burden imposed by the COVID-19 pandemic on our society triggered the race toward the development of therapies or preventive strategies. Among these, antibodies and vaccines are particularly attractive because of their high specificity, low ...
Giovanni Mazzocco, Iga Niemiec, Alexander Myronov, Alexander Myronov, Piotr Skoczylas, Jan Kaczmarczyk, Anna Sanecka-Duin, Katarzyna Gruba, Katarzyna Gruba, Paulina Król, Michał Drwal, Marian Szczepanik, Krzysztof Pyrc, Piotr Stȩpniak   +13 more
doaj   +1 more source

Clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease according to their epitopes

Frontiers in Neurology, 2023
BackgroundThe detection of myelin oligodendrocyte glycoprotein autoantibodies (MOG-Ab) is essential for the diagnosis of MOG-Ab-associated disease (MOGAD). The clinical implications of different epitopes recognized by MOG-Ab are largely unknown.
Jin Myoung Seok, Mi Young Jeon, Yeon Hak Chung, Yeon Hak Chung, Hyunjin Ju, Hyunjin Ju, Hye Lim Lee, Soonwook Kwon, Ju-Hong Min, Ju-Hong Min, Ju-Hong Min, Eun-Suk Kang, Byoung Joon Kim, Byoung Joon Kim   +13 more
doaj   +1 more source

Antibody screening reveals antigenic proteins involved in Talaromyces marneffei and human interaction

Frontiers in Cellular and Infection Microbiology, 2023
Talaromycosis is a fungal infection that generally affects immunocompromised hosts and is one of the most frequent systemic mycoses in HIV patients, especially in endemic areas such as Southeast Asia.
Tanaporn Wangsanut, Artid Amsri, Monsicha Pongpom   +2 more
doaj   +1 more source

Urinary Peptides As a Novel Source of T Cell Allergen Epitopes

Frontiers in Immunology, 2018
Mouse allergy in both laboratory workers and in inner-city children is associated with allergic rhinitis and asthma, posing a serious public health concern.
Ricardo da Silva Antunes, John Pham, Curtis McMurtrey, William H. Hildebrand, Elizabeth Phillips, Elizabeth Phillips, Simon Mallal, Simon Mallal, John Sidney, Paula Busse, Bjoern Peters, Bjoern Peters, Véronique Schulten, Alessandro Sette, Alessandro Sette   +14 more
doaj   +1 more source

B and T Cell Epitopes of the Incursionary Foot-and-Mouth Disease Virus Serotype SAT2 for Vaccine Development

Viruses, 2023
Failure of cross-protection among interserotypes and intratypes of foot-and-mouth disease virus (FMDV) is a big threat to endemic countries and their prevention and control strategies.
Qian Li, Ashenafi Kiros Wubshet, Yang Wang, Livio Heath, Jie Zhang   +4 more
doaj   +1 more source

In Silico Evaluation of a Mutant Toxic Shock Syndrome Toxin-1 (TSST-1) of Staphylococcus aureus as a Putative Vaccine Candidate [PDF]

Vaccine Research, 2020
Introduction: The development of a vaccine against Staphylococcus aureus has proven to be much more difficult than expected. In this study, we considered and analyzed a mutant Toxic Shock Syndrome Toxin-1 (TSST-1) as a potential vaccine candidate ...
Mohsen Nazari, Farzad Badmasti
doaj   +1 more source

Computational Approach for Predicting Common Epitopes in the VP1 Structural Protein of Enterovirus Serotypes EV-D68, EV-D70, and EV-A71

Journal of Pure and Applied Microbiology, 2021
The three human Enterovirus serotypes D-68, D-70, and A-71, are common pathogens that are transmitted by fecal-oral and aerosol routes. These positive RNA viruses were known to exhibit high levels of genetic diversity and variability.
Rihabe Boussettine, Yassine Kasmi, Najwa Hassou, Hlima Bessi, Moulay Mustapha Ennaji   +4 more
doaj   +1 more source

SARS-CoV-2 epitope-specific T cells: Immunity response feature, TCR repertoire characteristics and cross-reactivity

Frontiers in Immunology, 2023
The devastating COVID-19 pandemic caused by SARS-CoV-2 and multiple variants or subvariants remains an ongoing global challenge. SARS-CoV-2-specific T cell responses play a critical role in early virus clearance, disease severity control, limiting the ...
Gang Yang, Gang Yang, Gang Yang, Junxiang Wang, Ping Sun, Jian Qin, Xiaoyun Yang, Xiaoyun Yang, Daxiang Chen, Daxiang Chen, Yunhui Zhang, Nanshan Zhong, Nanshan Zhong, Nanshan Zhong, Zhongfang Wang, Zhongfang Wang   +15 more
doaj   +1 more source

Predicted Peptides from Non-Structural Proteins of Porcine Reproductive and Respiratory Syndrome Virus Are Able to Induce IFN-γ and IL-10

Viruses, 2013
This work describes peptides from non-structural proteins (nsp) of porcine reproductive and respiratory syndrome virus (PRRSV) predicted as potential T cell epitopes by bioinfornatics and tested for their ability to induce IFN-γ and IL-10 ...
Enric Mateu, Jesús Hernández, Sabine E. Essler, Irene M. Rodríguez-Gómez, Alexel Burgara-Estrella, Ivan Díaz   +5 more
doaj   +1 more source