Results 11 to 20 of about 241,882 (308)

BCEPS: A Web Server to Predict Linear B Cell Epitopes with Enhanced Immunogenicity and Cross-Reactivity

Cells, 2021
Prediction of linear B cell epitopes is of interest for the production of antigen-specific antibodies and the design of peptide-based vaccines. Here, we present BCEPS, a web server for predicting linear B cell epitopes tailored to select epitopes that ...
Alvaro Ras-Carmona, Hector F. Pelaez-Prestel, Esther M. Lafuente, Pedro A. Reche   +3 more
doaj   +2 more sources

HLA-B*35-restricted CD8 T cell epitopes in the antigen 85 complex of Mycobacterium tuberculosis. [PDF]

, 2001
Few target epitopes have been described for human CD8 T lymphocytes in antigens of Mycobacterium tuberculosis. By use of a reverse immunogenetics approach, 23 motif-bearing peptides of the Ag85 complex were tested for binding to HLA-B*35, one of the ...
Ogg, GS, Jaye, A, Klein, MR, Lukey, PT, Hammond, AS, King, AS, McAdam, KP, Vekemans, J, Smith, SM   +8 more
core   +2 more sources

Anaplasma marginale major surface protein 2 CD4+-T-cell epitopes are evenly distributed in conserved and hypervariable regions (HVR), whereas linear B-cell epitopes are predominantly located in the HVR [PDF]

, 2004
Organisms in the genus Anaplasma express an immunodominant major surface protein 2 (MSP2), composed of a central hypervariable region (HVR) flanked by highly conserved regions.
Abbott, Jeffrey R, Brown, Wendy C, Howard, Chris J, Palmer, Guy H, Brown, Wendy C., Hope, Jayne; id_orcid, Hope, Jayne C   +6 more
core   +1 more source

Epitope Tagging [PDF]

BioTechniques, 2008
Epitope tagging is widely used in the characterization of newly discovered proteins. This review presents an overview of how the technique evolved and how it is being used today, with a focus on its use in the study of protein-protein interactions. In addition, the evolution of the technique for proteomic analyses is described.
openaire   +3 more sources

Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate [PDF]

, 2012
The majority of broadly neutralizing antibodies to hepatitis C virus (HCV) are against conformational epitopes on the E2 glycoprotein. Many of them recognize overlapping epitopes in a cluster, designated as antigenic domain B, that contains residues G530
Wenyan Wang (171659), Bukh, J., Felix A Rey, Yong Wang (12837), Wang, Yong, Zhen-yong Keck (171653), Jannick Prentoe (162323), Lemon, S.M., Jannick Prentoe, Jens Bukh (162343), Steven K. H. Foung (171667), Lemon, Stanley M., Prentoe Jannick, Foung Steven K. H., Thomas Carlsen (171662), Carlsen, Thomas, Rey, F.A., Patel, Arvind H., Li, A.Y., Patel, A.H., Steven K H Foung, Carlsen Thomas, Bukh, Jens, Xia, J., Zhen-yong Keck, Li, Angela Ying-Jian, Wenyan Wang, Keck, Zhen-yong, Thomas Krey, Wang, Y., Rey Felix A., Yong Wang, Foung, S.K.H., Arvind H. Patel (33806), Patel, Arvind H, Lemon, Stanley M, Krey Thomas, Keck Zhen-yong, Wang Wenyan, Rey, Felix A., Prentoe, Jannick, Arvind H Patel, Bukh Jens, Stanley M Lemon, Krey, T., Angela Ying-Jian Li, Felix A. Rey (171664), Foung, Steven K H, Thomas Krey (171661), Keck, Z., Xia Jinming, Krey, Thomas, Jinming Xia (171656), Stanley M. Lemon (30543), Wang, Wenyan, Lemon Stanley M., Patel Arvind H., Rey, Felix A, Li Angela Ying-Jian, Jinming Xia, Xia, Jinming, Foung, Steven K. H., Thomas Carlsen, Wang, W., Prentoe, J., Jens Bukh, Angela Ying-Jian Li (171663), Carlsen, T., Wang Yong   +68 more
core   +1 more source

Hepatitis C virus (HCV) infection may elicit neutralizing antibodies targeting epitopes conserved in all viral genotypes [PDF]

, 2009
Anti-hepatitis C virus (HCV) cross-neutralizing human monoclonal antibodies, directed against conserved epitopes on surface E2 glycoprotein, are central tools for understanding virus-host interplay, and for planning strategies for prevention and ...
Patel, Ah, Ball Jonathan K., Nicasio Mancini, Nicola Clementi, Sautto, G, Clementi, N., Ball, J.K., Diotti, R.A., Burioni, R., Mario Perotti, Arvind H Patel, Nitti Giovanni, Diotti, Ra, Clementi Massimo, CLEMENTI, NICOLA, BURIONI, ROBERTO, Sautto, G., CLEMENTI, MASSIMO, Perotti, M., Jonathan K Ball, Massimo Clementi, Nitti, G, Giovanni Nitti, Patel, A.H., Clementi, M., Perotti Mario, Ball, Jk, Perotti, M, Patel Arvind H., Roberta A Diotti, Giuseppe Sautto, Mancini Nicasio, Diotti Roberta A., Mancini, N., Roberto Burioni, Sautto Giuseppe, MANCINI, NICASIO, Clementi Nicola, Burioni Roberto, Nitti, G.   +39 more
core   +1 more source

Epitope Identification in BEFV Gene for Detecting Effective Points [PDF]

Journal of Advanced Biomedical Sciences, 2022
Background & Objective: The most common cause of milk production loss in cattle and water buffalo is bovine ephemeral fever (BEF). Previous cases have been reported in Iran's south regions, with a low mortality rate.
Shima Molazadeh, Hadi Keivanfar, Mehran Bakhshesh, Gholamreza Nikbakht Brujeni   +3 more
doaj  

Seeking Flavivirus Cross-Protective Immunity

Frontiers in Immunology, 2019
The Flavivirus genus is composed by viral serocomplexes with relevant global epidemiological impact. Many areas of the world present both, vector fauna and geographical conditions compatible with co-circulation, importing, emergence, and epidemics of ...
Lorrany dos Santos Franco, Letícia Tsieme Gushi, Wilson Barros Luiz, Jaime Henrique Amorim, Jaime Henrique Amorim   +4 more
doaj   +1 more source

Preparation and Identification of a Monoclonal Antibody against the Pseudorabies Virus gE Glycoprotein through a Novel Strategy

Veterinary Sciences, 2023
Since 2011, pseudorabies virus (PRV) has recurred in several vaccinated pig farms in China. PRV variants with high virulence were found to be the main cause of the outbreaks.
Zhenyang Guo, Siyu Zhang, Hu Xu, Wansheng Li, Chao Li, Jing Zhao, Bangjun Gong, Qi Sun, Lirun Xiang, Hongyuan Zhao, Qian Wang, Guohui Zhou, Yandong Tang, Tongqing An, Xuehui Cai, Zhijun Tian, Hongliang Zhang, Jinmei Peng   +17 more
doaj   +1 more source

Epitope spreading

Current Opinion in Immunology, 1996
Epitope (determinant) spreading is the development of immune responses to endogenous epitopes secondary to the release of self antigens during a chronic autoimmune or inflammatory response. The past year has seen considerable advances in our understanding of the contribution of epitope spreading to the chronic pathogenesis of experimental T-cell ...
Vanderlugt, Carol J, Miller, Stephen D
openaire   +2 more sources