Results 11 to 20 of about 258,671 (306)

BCEPS: A Web Server to Predict Linear B Cell Epitopes with Enhanced Immunogenicity and Cross-Reactivity

Cells, 2021
Prediction of linear B cell epitopes is of interest for the production of antigen-specific antibodies and the design of peptide-based vaccines. Here, we present BCEPS, a web server for predicting linear B cell epitopes tailored to select epitopes that ...
Alvaro Ras-Carmona, Hector F. Pelaez-Prestel, Esther M. Lafuente, Pedro A. Reche   +3 more
doaj   +2 more sources

Identification of B-Cell Linear Epitopes on pE146L Protein of African Swine Fever Virus Using Monoclonal Antibodies. [PDF]

Microorganisms
African swine fever virus (ASFV) is a highly pathogenic DNA virus that continues to circulate globally and poses a serious threat to the swine industry.
Wang A, Yuan Y, Wang H, Yan W, Liu X, Wang Y, Qi Y, Chen Y, Zhu X, Zhang G.   +9 more
europepmc   +2 more sources

Mutation Profile of HPV16 L1 and L2 Genes in Different Geographic Areas

Viruses, 2022
The causal relationship between HPV and cervical cancer in association with the high prevalence of high risk HPV genotypes led to the design of HPV vaccines based on the major capsid L1 protein.
Dimitris Tsakogiannis, Marios Nikolaidis, Flora Zagouri, Eleni Zografos, Christine Kottaridi, Zaharoula Kyriakopoulou, Lamprini Tzioga, Panayotis Markoulatos, Grigoris D. Amoutzias, Garyfalia Bletsa   +9 more
doaj   +1 more source

AI Aided Design of Epitope-Based Vaccine for the Induction of Cellular Immune Responses Against SARS-CoV-2

Frontiers in Genetics, 2021
The heavy burden imposed by the COVID-19 pandemic on our society triggered the race toward the development of therapies or preventive strategies. Among these, antibodies and vaccines are particularly attractive because of their high specificity, low ...
Giovanni Mazzocco, Iga Niemiec, Alexander Myronov, Alexander Myronov, Piotr Skoczylas, Jan Kaczmarczyk, Anna Sanecka-Duin, Katarzyna Gruba, Katarzyna Gruba, Paulina Król, Michał Drwal, Marian Szczepanik, Krzysztof Pyrc, Piotr Stȩpniak   +13 more
doaj   +1 more source

Clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease according to their epitopes

Frontiers in Neurology, 2023
BackgroundThe detection of myelin oligodendrocyte glycoprotein autoantibodies (MOG-Ab) is essential for the diagnosis of MOG-Ab-associated disease (MOGAD). The clinical implications of different epitopes recognized by MOG-Ab are largely unknown.
Jin Myoung Seok, Mi Young Jeon, Yeon Hak Chung, Yeon Hak Chung, Hyunjin Ju, Hyunjin Ju, Hye Lim Lee, Soonwook Kwon, Ju-Hong Min, Ju-Hong Min, Ju-Hong Min, Eun-Suk Kang, Byoung Joon Kim, Byoung Joon Kim   +13 more
doaj   +1 more source

Antibody screening reveals antigenic proteins involved in Talaromyces marneffei and human interaction

Frontiers in Cellular and Infection Microbiology, 2023
Talaromycosis is a fungal infection that generally affects immunocompromised hosts and is one of the most frequent systemic mycoses in HIV patients, especially in endemic areas such as Southeast Asia.
Tanaporn Wangsanut, Artid Amsri, Monsicha Pongpom   +2 more
doaj   +1 more source

Anaplasma marginale major surface protein 2 CD4+-T-cell epitopes are evenly distributed in conserved and hypervariable regions (HVR), whereas linear B-cell epitopes are predominantly located in the HVR [PDF]

, 2004
Organisms in the genus Anaplasma express an immunodominant major surface protein 2 (MSP2), composed of a central hypervariable region (HVR) flanked by highly conserved regions.
Abbott, Jeffrey R, Brown, Wendy C, Howard, Chris J, Palmer, Guy H, Brown, Wendy C., Hope, Jayne; id_orcid, Hope, Jayne C   +6 more
core   +1 more source

Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate [PDF]

, 2012
The majority of broadly neutralizing antibodies to hepatitis C virus (HCV) are against conformational epitopes on the E2 glycoprotein. Many of them recognize overlapping epitopes in a cluster, designated as antigenic domain B, that contains residues G530
Wenyan Wang (171659), Bukh, J., Felix A Rey, Yong Wang (12837), Wang, Yong, Zhen-yong Keck (171653), Jannick Prentoe (162323), Lemon, S.M., Jannick Prentoe, Jens Bukh (162343), Steven K. H. Foung (171667), Lemon, Stanley M., Prentoe Jannick, Foung Steven K. H., Thomas Carlsen (171662), Carlsen, Thomas, Rey, F.A., Patel, Arvind H., Li, A.Y., Patel, A.H., Steven K H Foung, Carlsen Thomas, Bukh, Jens, Xia, J., Zhen-yong Keck, Li, Angela Ying-Jian, Wenyan Wang, Keck, Zhen-yong, Thomas Krey, Wang, Y., Rey Felix A., Yong Wang, Foung, S.K.H., Arvind H. Patel (33806), Patel, Arvind H, Lemon, Stanley M, Krey Thomas, Keck Zhen-yong, Wang Wenyan, Rey, Felix A., Prentoe, Jannick, Arvind H Patel, Bukh Jens, Stanley M Lemon, Krey, T., Angela Ying-Jian Li, Felix A. Rey (171664), Foung, Steven K H, Thomas Krey (171661), Keck, Z., Xia Jinming, Krey, Thomas, Jinming Xia (171656), Stanley M. Lemon (30543), Wang, Wenyan, Lemon Stanley M., Patel Arvind H., Rey, Felix A, Li Angela Ying-Jian, Jinming Xia, Xia, Jinming, Foung, Steven K. H., Thomas Carlsen, Wang, W., Prentoe, J., Jens Bukh, Angela Ying-Jian Li (171663), Carlsen, T., Wang Yong   +68 more
core   +1 more source

Urinary Peptides As a Novel Source of T Cell Allergen Epitopes

Frontiers in Immunology, 2018
Mouse allergy in both laboratory workers and in inner-city children is associated with allergic rhinitis and asthma, posing a serious public health concern.
Ricardo da Silva Antunes, John Pham, Curtis McMurtrey, William H. Hildebrand, Elizabeth Phillips, Elizabeth Phillips, Simon Mallal, Simon Mallal, John Sidney, Paula Busse, Bjoern Peters, Bjoern Peters, Véronique Schulten, Alessandro Sette, Alessandro Sette   +14 more
doaj   +1 more source

B and T Cell Epitopes of the Incursionary Foot-and-Mouth Disease Virus Serotype SAT2 for Vaccine Development

Viruses, 2023
Failure of cross-protection among interserotypes and intratypes of foot-and-mouth disease virus (FMDV) is a big threat to endemic countries and their prevention and control strategies.
Qian Li, Ashenafi Kiros Wubshet, Yang Wang, Livio Heath, Jie Zhang   +4 more
doaj   +1 more source