Results 191 to 200 of about 2,440,973 (235)

Anti-Streptavidin IgG Antibody Interference in Anti-Cyclic Citrullinated Peptide (CCP) IgG Antibody Assays Is a Rare but Important Cause of False-Positive Anti-CCP Results

Clinical Chemistry and Laboratory Medicine, 2018
Background: The detection of anti-cyclic citrullinated peptide (anti-CCP) IgG antibodies in blood is mainly used for the diagnosis of rheumatoid arthritis. Falsely elevated anti-CCP IgG antibodies due to anti-streptavidin IgG antibodies were suspected in
Mario Berth
exaly   +2 more sources

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Anti-CCP Biosensors in Rheumatoid Arthritis

Clinica Chimica Acta
Biosensors are unique analytical tools for the detection of biomarkers. Of these, autoantibodies against citrullinated proteins (ACPA) are useful for the differential diagnosis of rheumatoid arthritis (RA). The autoantibodies may be detected by immunoassay technology using synthetic cyclic citrullinated peptides (CCP), ie, anti-CCP.
Mohammad Johari-Ahar, Farzaneh Fathi
exaly   +3 more sources

The Continuous Measurement of Anti-CCP-Antibodies Does Not Help to Evaluate the Disease Activity in Anti-CCP-Antibody-Positive Patients With Rheumatoid Arthritis

Clinical Rheumatology, 2010
Anti-cyclic citrullinated peptide antibody (CCP-AB) are used for diagnosis of rheumatoid arthritis (RA). It is still unknown if the extent of CCP-AB levels is useful to assess the disease activity or the individual follow-up as an individual activity parameter. We investigated 40 patients with a known RA who were positive for CCP-AB.
Raoul Bergner
exaly   +3 more sources

Redefining the HLA and RA association: To be or not to be anti-CCP positive

Journal of Autoimmunity, 2005
Rheumatoid Arthritis (RA) is the most common chronic inflammatory joint disease. The overall prevalence is 1% and in people older than 60 it is more than 2%. RA has auto-immune features: auto-antibodies against the Fc part of IgG, so-called Rheumatoid Factor (RF) are found more often in RA patients and more recently RA-specific auto-antibodies directed
René R P, de Vries, Tom W J, Huizinga, René E M, Toes   +2 more
openaire   +2 more sources

The role of the shared epitope in arthralgia with anti-cyclic citrullinated peptide antibodies (anti-CCP), and its effect on anti-CCP levels

Annals of the Rheumatic Diseases, 2008
Patients presenting with both arthralgia and antibodies to cyclic citrullinated peptide (anti-CCP) have an increased risk of developing rheumatoid arthritis (RA). To further characterise this patient group and shed more light on its relationship with clinically manifest early arthritis and established RA, an immunogenetic and serological analysis was ...
Bos, W. H., Ursum, J., de Vries, N. [=Niek], Bartelds, G. M., Wolbink, G. J., Nurmohamed, M. T., van der Horst-Bruinsma, I. E., van de Stadt, R. J., Crusius, J. B. A., Tak, P. P., Dijkmans, B. A. C., van Schaardenburg, D.   +11 more
openaire   +4 more sources

High Positivity of Anti-CCP Antibodies in Patients With Down Syndrome

Clinical Rheumatology, 2007
The aim of the present study was to evaluate the prevalence of anti-cyclic citrullinated peptide (CCP) antibodies in patients with Down's syndrome (DS) previously tested for IgM rheumatoid factor (RF) and to correlate the results with clinical findings.
Renato M. Nisihara, Thelma L Skare, Shirley Ramos da Rosa Utiyama   +2 more
exaly   +3 more sources

Rheumatoid Arthritis, Proteus, Anti-CCP Antibodies and Karl Popper

Autoimmunity Reviews, 2010
Rheumatoid arthritis (RA) is a crippling joint disease affecting over 20 million people worldwide. The cause of RA is most probably linked to the triad of microbial trigger, genetic association and autoimmunity and can be explained using the philosophical method of Karl Popper or Popperian sequences.
Alan Ebringer, Clyde Wilson, Taha Rashid
exaly   +4 more sources

Rheumatoid Factor and Anti-CCP Titers in COVID-19

Infectious Disorders - Drug Targets
Introduction: The mechanisms of Coronavirus Disease 2019 (COVID-19) remain not fully elucidated. The present study aimed to trace the presence of autoantibodies among COVID-19 patients and to determine the association between COVID-19 and these antibodies.
Mudathir Abdelshafea Abdelkareem Abakar, Mohamed Ibrahim Awadab, Zohair Khalid Ibrahim Elaraki, Mohammed Elsheikh Osman, Mohamed Ahmed Ibrahim–Holi, Eltayib Hassan Ahmed-Abakur, Tarig M. S. Alnour   +6 more
openaire   +2 more sources

Clinical Utility of the Anti‐CCP Assay: Experiences with 700 Patients

Annals of the New York Academy of Sciences, 2005
Abstract: Our objective was to determine the frequency of antibodies to cyclic citrullinated peptides (CCPs) in a series of patients with a variety of rheumatic diseases. Seven hundred consecutive serum samples from patients at an outpatient clinic were tested for the presence of rheumatoid factor (RF) and anti‐CCP.
Ulrich, Sauerland, Heidemarie, Becker, Matthias, Seidel, Heiko, Schotte, Peter, Willeke, Annette, Schorat, Bernhard, Schlüter, Wolfram, Domschke, Markus, Gaubitz   +8 more
openaire   +2 more sources