Results 71 to 80 of about 2,440,973 (235)

Cartilage Oligomeric Matrix Protein Associates Differentially with Erosions and Synovitis and Has a Different Temporal Course in Cyclic Citrullinated Peptide Antibody (Anti-CCP)-positive versus Anti-CCP-negative Early Rheumatoid Arthritis [PDF]

, 2011
Objective.Cyclic citrullinated peptide antibody (anti-CCP)-positive and anti-CCP-negative rheumatoid arthritis (RA) have been suggested as 2 distinctive disease subsets with respect to disease activity and prognosis. Previously, we proposed that anti-CCP
Jacobsen, Søren, Østergaard, Mikkel, Junker, Michael Peter, Lindegaard, Hanne, Ejbjerg, Bo Jannik, JENS K. PEDERSEN, Christensen, Anne F, Pedersen, Jens K, Svendsen, Anders, HENRIK SKJØDT, Pedersen, Jens K; id_orcid, Ostergaard, Mikkel, Pødenphant, Jan, Hansen, Ib, ULRIK TARP, SØREN JACOBSEN, ANDERS SVENDSEN, Junker, Peter, Hansen, Ib Tønder, TINE LOTTENBURGER, HANNE LINDEGAARD, KIM HØRSLEV-PETERSEN, BO EJBJERG, Andersen, Lis S, Ejbjerg, Bo, Skjødt, Henrik, JAN PØDENPHANT, PETER JUNKER, Ellingsen, Torkell Juulsgaad, Hetland, Merete Lund, Hørslev-Petersen, Kim, IB HANSEN, Ellingsen, Torkell Juulsgaad; id_orcid, Stengaard-Pedersen, Kristian, KRISTIAN STENGAARD-PEDERSEN, Lauridsen, Ulrik Birk, MERETE L. HETLAND, Lottenburger, Tine, ULRIK B. LAURIDSEN, Svendsen, Anders; id_orcid, ANNE F. CHRISTENSEN, MIKKEL ØSTERGAARD, Andersen, Lis Abildgaard, LIS S. ANDERSEN, Hetland, Merete L, TORKELL ELLINGSEN, Tarp, Ulrik, Lauridsen, Ulrik B   +47 more
core   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Correlation between Anti-CCP Titer and Body Mass Index Score in Rheumatoid Arthritis Patients in Cipto Mangunkusumo Hospital

Indonesian Journal of Rheumatology, 2018
Background: Rheumatoid Arthritis (RA) is a chronic systemic inflammation that attacks and damages joints of upper and lower extremities. RA causes morbidity and disability, hence, affects the quality of life.
Harry Isbagio, Khadijah Fitriah
doaj   +1 more source

Clinical Significance of Anti-CCP Antibodies in Rheumatoid Arthritis

Internal Medicine, 2005
A number of novel autoantibodies have been recently described in rheumatoid arthritis (RA), and their clinical significance and possible pathogenic roles have been discussed. In particular, new autoantibodies to citrullinated proteins such as filaggrin and its circular form (cyclic citrullinated peptide: CCP) are especially noteworthy because of their ...
openaire   +3 more sources

Chemistry Underlying the Behavior of Food and Agricultural Components During Industrial Manufacturing Processes and Its Implications in Quality Assurance, Food Quality, and Food Safety Management: A Systematic Review

Food Safety and Health, EarlyView.
Industrial manufacturing processes have transformative effects on the components of food matrix. These transformations in food matrix and components have direct implications for quality assurance (QA), food quality (e.g., nutritional profile and texture), and food safety management (e.g., pathogen control and toxin mitigation). ABSTRACT This systematic
Chinaza Godswill Awuchi
wiley   +1 more source

Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer

International Journal of Cancer, EarlyView.
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue, Daniele Carchidi, Philipp Schmucker, Roland Seiler, Bernhard Kiss, Catarina Macedo‐Silva, Marianna Kruithof‐de Julio   +6 more
wiley   +1 more source

Anti-cyclic citrullinated peptide antibodies – a role in rheumatoid arthritis and the possibility of seroconversion: A focus on abatacept

Современная ревматология, 2017
The detection of anti-cyclic citrullinated peptide (anti-CCP) antibodies plays a diagnostic and statistical predictive role in rheumatoid arthritis (RA).
N. V. Chichasova
doaj   +1 more source

Gene Expression Biomarkers for Breast Ductal Carcinoma in Situ Recurrence Prediction

International Journal of Cancer, EarlyView.
ABSTRACT Breast ductal carcinoma in situ (DCIS) is often overtreated due to a lack of robust prognostic and predictive tools. This study aimed to evaluate gene expression in a well‐characterised DCIS cohort to determine their clinical utility as biomarkers for ipsilateral recurrence. RNA was extracted from microdissected tissues from primary DCIS.
Alexandria Un, Sakshi Mahale, David Byrne, Dorothea Lesche, Carlos Martinez‐Perez, Jia‐Min Pang, Maree Pechlivanis, Hugo Saunders, Madawa W. Jayawardana, Tongtong Luo, Sureshni I. Jayasinghe, Tanjina Kader, Lisa Devereux, Puay Hoon Tan, Andrew R. Green, Emad A. Rakha, Arran K. Turnbull, Stephen B. Fox, G. Bruce Mann, Kylie L. Gorringe   +19 more
wiley   +1 more source

Anti-CCP antibodies: A Better Diagnostic Tool for Rheumatoid Arthritis [PDF]

, 2009
Introduction: Rheumatoid factors are currently used in the diagnosis of rheumatoid arthritis and constitute one of the classification criteria proposed by the American College of Rheumatology. However, rheumatoid factor positivity shows low diagnostic
Hussin, Che Maraina Che
core   +1 more source

Comparism between Anti-RA33, Anti-CCP antibodies and Rheumatoid Factor in the Diagnosis of Rheumatoid Arthritis in Iraqi Patients

مجلة كلية الطب, 2013
Background: Anti-RA33 antibodies and anti-CCP antibodies are highly specific markers for rheumatoid arthritis (RA), but are not detectable in all RA patients.
Ammar H. Al-Ubaidi, Mohammed Marrof Al-Ani, Khudhayer Z. Al-Bidri   +2 more
doaj   +1 more source