Results 61 to 70 of about 2,440,973 (235)
Advanced Science, EarlyView.Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su +13 more
wiley +1 more source
Analytical and diagnostic performance of an automated anti-CCP assay
, 2011 AIM: Autoantibodies against cyclic citrullinated peptide (anti-CCP) are considered to be a sensitive and specific marker for rheumatoid arthritis (RA).
Chow, S.K. +3 more
core +2 more sources
Arthritis &Rheumatology, EarlyView.Objective Disease activity plays a central role in rheumatoid arthritis (RA) clinical studies. The inconsistent availability of data on disease activity in real‐world electronic health records (EHRs) data has limited the ability to generate real‐world evidence (RWE).
David Cheng +34 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA) and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serologic markers. Methods We analyzed serum and plasma from three cohorts: presymptomatic individuals who later developed RA ...
Outi Sareila +12 more
wiley +1 more source
Anti-citrullinated protein antibodies in the diagnosis of rheumatoid arthritis (RA): diagnostic performance of automated anti-CCP-2 and anti-CCP-3 antibodies assays. [PDF]
Clin Rheumatol, 2017 This study compares the diagnostic performance of a second generation anti-cyclic citrullinated peptide antibody (CCP2) with a third generation anti-CCP antibodies assay (CCP3), as well as the combination of both tests. Serum samples of 127 patients were analyzed.
Vos I +7 more
europepmc +6 more sources
Arthritis &Rheumatology, EarlyView.Objective Microbial small RNAs can regulate human genes. Higher plasma concentrations of microbial transfer RNA (tRNA)‐derived RNA‐1 (tDR‐1) were previously associated with lower rheumatoid arthritis (RA) disease activity. This study examined whether tDR‐1 concentrations differ in anticyclic citrullinated peptide‐3 positive (CCP3+) at‐risk individuals (
Anastasiia Phothisane +11 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective The aim of this study was to investigate the prevalence and longitudinal evolution of anti–carbamylated fibrinogen antibodies (ACa‐Fib) of IgG and IgA isotypes in early rheumatoid arthritis (RA) and determine whether these antibodies provide additional diagnostic and prognostic information beyond anti–cyclic citrullinated peptide (anti‐CCP ...
Pauline Brevet +11 more
wiley +1 more source
Bispecific antibodies (BsAb) and anti-CCP assay in mixing tests.
, 2013 (A) One anti-CCP-positive but BsAb-negative serum (#32) was mixed with different dilutions of one RF predominant serum (#3); concentrations of BsAb and anti-CCP in the mixtures were determined.
Jinming Li (128865), Wei Wang (17594)
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Evidence supporting tapering of biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) in patients with rheumatoid arthritis (RA) with sustained low disease activity (LDA) remains limited. We evaluated the efficacy and safety of a structured b/tsDMARD‐tapering strategy in patients with RA who had achieved sustained ...
Dong‐Jin Park +19 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Tissue‐resident memory T (TRM) cells have been implicated in organ‐specific immune pathology; however, the pathologic relevance of TRM‐like CD8+ T cells in systemic lupus erythematosus (SLE) remains unclear. We investigated their differentiation mechanisms and pathologic significance in SLE, including associations with disease activity and ...
Yuya Fujita +10 more
wiley +1 more source