Results 91 to 100 of about 2,088,605 (164)

PARTY‐STATE URBANISM: Coevolution of Local State Capacity and Strategic Alliances in Shenzhen

International Journal of Urban and Regional Research, EarlyView.
Abstract What is distinct about Chinese urban governance? Classic theories predict that when the central state retreats from resource allocation, capacity‐strained local governments must form alliances with non‐state actors, thereby diluting state power. In China, however, state power remains dominant despite decentralization.
Yunhan Wen
wiley   +1 more source

Prevalence of anti-CCP antibodies in systemic sclerosis

, 2007
Joint involvement in systemic sclerosis (SSc) commonly occurs as arthralgias, while a true arthritis is less frequent. The most common arthritis developing in SSc is rheumatoid arthritis (RA) and its diagnosis may be misled by concomitant joint ...
N. Pansini, RAHO L, F. Iannone, CHIALA' A, LAPADULA, Giovanni, M. Covelli, G. Lapadula, GRATTAGLIANO V, IANNONE, Florenzo, MARRONE M, COVELLI M, L. Raho, M. Tampoia, A. Chialà, M. Marrone, TAMPOIA M, PANSINI N, V. Grattagliano   +17 more
core   +1 more source

Sixteen Years Later: Revisiting Cultural Complexes and the Roots of Archetypal Thematic Analysis (ATA)1

Journal of Analytical Psychology, EarlyView.
Abstract Written as a letter to my 28‐year‐old self, this paper explores the development of my engagement with cultural complexes. On August 18, 2009, I finished a chapter applying cultural complexes to a history of China, complete with elaborate charts that seemed to confirm a process by which cultural complexes are formed, and how China’s then recent
Kevin Lu
wiley   +1 more source

Olfactory proteomics reveals the capacity of the HDAC1 inhibitor pyroxamide to halt the α‐synuclein preformed fibrils‐induced damage in nasal epithelial, microglial and dopaminergic neuronal cell lines

Brain Pathology, EarlyView.
Omics‐driven drug repositioning reveals pyroxamide as a neuroprotective HDAC1 inhibitor in Parkinson's disease models. Abstract Parkinson's disease (PD) is the second most common neurodegenerative disorder mainly characterized by the degeneration of dopaminergic neurons originating in the substantia nigra (SN) pars compacta and projecting to other ...
Paz Cartas‐Cejudo, Marina De Miguel, Leire Extramiana, Mercedes Lachén‐Montes, Silvia Romero‐Murillo, Djordje Gveric, Joaquín Fernández‐Irigoyen, Enrique Santamaría   +7 more
wiley   +1 more source

单独检测抗环瓜氨酸肽抗体以诊断类风湿关节炎

Zhongguo shiyan zhenduanxue, 2014
目的分别评价单独和联合检测抗环瓜氨酸肽抗体（anti-CCP）和类风湿因子（RF）等临床指标在诊断类风湿关节炎（RA）中的作用。方法速率散射比浊法检测RF;酶联免疫吸附试验（ELISA）检测anti-CCP;间接免疫荧光法检测抗角蛋白抗体（AKA）和抗核周因子抗体（APF）。结果 anti-CCP的敏感性与RF相比无显著性差异（P>0.05）,但特异性显著高于RF（P0.05）,特异性却显著下降（P0.05）,检测anti-CCP/RF/AKA/APF,特异性显著下降（P0.05）,但敏感性均显著下降 ...
葛艳玲, 宋慧, 赵育靖
doaj  

A De Novo ATP1A3 p.Arg995His Variant in a Patient With an Adult‐Onset Primary Lateral Sclerosis‐Like Syndrome

Clinical Genetics, EarlyView.
A 43‐year‐old woman developed a progressive adult‐onset upper motor neuron syndrome fulfilling the clinical criteria for primary lateral sclerosis (PLS), with mild cerebellar involvement. Genetic testing identified a de novo ATP1A3 p.Arg995His variant affecting a highly conserved residue within the transmembrane M8 domain.
Pablo Hernandez‐Vitorique, Marta García de Burgos, Ana Campos Villegas, María José Gómez Heredia, Pilar Carbonell Corvillo   +4 more
wiley   +1 more source

Human host defence peptide LL37 and anti-cyclic citrullinated peptide antibody in early inflammatory arthritis

RMD Open, 2019
Objective Antibodies to citrullinated peptides (anti-CCP) develop in individuals predisposed to rheumatoid arthritis (RA). Neutrophil extracellular traps are a major source of citrullinated antigens and the immunomodulatory host defence peptide LL-37 ...
Carol A Hitchon, Xiaobo Meng, Hani S El Gabalawy, Linda Larcombe   +3 more
doaj   +1 more source

Direct transition to a streamlined rheumatoid arthritis clinic improves outcomes after discharge from an early arthritis clinic environment

Internal Medicine Journal, EarlyView.
Abstract Background The treat‐to‐target (T2T) strategy for the management of rheumatoid arthritis (RA) achieves remission or low disease activity in many patients. However, RA T2T is challenging in real‐world clinical environments. In this two‐stage audit, we evaluated the impact of transferring patients from a T2T intensive early arthritis clinic (EAC)
Hyunjun Jonathan Kim, Mitsi Blazos, Kevin Yen Chia Su, Ranjeny Thomas, Helen Benham   +4 more
wiley   +1 more source

Treatment strategies for interstitial granulomatous dermatitis: Systematic review and expert opinion

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Systematic review of 108 studies with a total of 182 patients with interstitial granulomatous dermatitis (IGD). IGD was frequently associated with systemic conditions or drug exposure. Management includes careful medication review and prompt withdrawal of potential triggers. Corticosteroids (systemic and topical) were commonly effective, while biologic
Francesco Bellinato, Sara Salvagno, Chiara Colato, Paolo Gisondi, Giampiero Girolomoni   +4 more
wiley   +1 more source

ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODIES IN RHEUMATOID ARTHRITIS PATIENTS

Pakistan Armed Forces Medical Journal, 2018
Objective: To detect the anti cyclic citrullinated peptide (Anti-CCP) antibody in rheumatoid arthritis (RA) patients to determine its diagnostic value in Pakistani patients. Study Design: Cross sectional study.
Amer Fakhr, Farzana Hakim, Mushtaq Ahmed, Mukarram Bashir, Rabia Basri   +4 more
doaj   +2 more sources