Results 51 to 60 of about 2,088,605 (164)

Comparative Evaluation of Rheumatoid Factor and Anti-CCP Antibody Tests as Diagnostic Markers for Rheumatoid Arthritis: A Cross-sectional Study from a Tertiary Care Centre in Dehradun, Uttarakhand, India [PDF]

National Journal of Laboratory Medicine
Introduction: Rheumatoid Arthritis (RA) is a chronic autoimmune disease with a global prevalence of approximately 1%. It is characterised by persistent joint inflammation and the production of multiple autoantibodies, leading to joint destruction ...
Yogita Rawat, Arti Negi, Pavneesh Kumar, Nidhi Negi, Nidhi Rana, Shalabh Jauhari   +5 more
doaj   +1 more source

Anti–Carbamylated Fibrinogen Autoantibodies of IgG and IgA Isotypes Contribute to a Better Prognostic Stratification in Very Early Rheumatoid Arthritis: Data From the French National ESPOIR Cohort

Arthritis &Rheumatology, EarlyView.
Objective The aim of this study was to investigate the prevalence and longitudinal evolution of anti–carbamylated fibrinogen antibodies (ACa‐Fib) of IgG and IgA isotypes in early rheumatoid arthritis (RA) and determine whether these antibodies provide additional diagnostic and prognostic information beyond anti–cyclic citrullinated peptide (anti‐CCP ...
Pauline Brevet, Olivia Guérin, Léna Le Goaréguer, Élisa Halbourg, Marie‐Laure Golinski, Sophie Candon, Olivier Boyer, Thierry Lequerré, Thierry Schaeverbeke, Valérie Devauchelle‐Pensec, Olivier Vittecoq, Manuel Fréret   +11 more
wiley   +1 more source

Citrullinated Antigens with Multiple Citrulline Similar Motif in the Diagnosis of Rheumatoid Arthritis: A Preliminary Single-Center Study

Journal of Immunology Research, 2021
The presence of anti-citrullinated protein antibodies (ACPAs) in the serum is one of the immunological features of rheumatoid arthritis (RA). Anti-cyclic citrullinated peptide (CCP) assay has been widely used in clinic for the diagnosis of RA.
Zhu Chen, Weiting Fang, Yi Qin, Yin-Zhao Jin, Xiang Yang, Jianrong Lou   +5 more
doaj   +1 more source

Cartilage Oligomeric Matrix Protein Associates Differentially with Erosions and Synovitis and Has a Different Temporal Course in Cyclic Citrullinated Peptide Antibody (Anti-CCP)-positive versus Anti-CCP-negative Early Rheumatoid Arthritis [PDF]

, 2011
Objective.Cyclic citrullinated peptide antibody (anti-CCP)-positive and anti-CCP-negative rheumatoid arthritis (RA) have been suggested as 2 distinctive disease subsets with respect to disease activity and prognosis. Previously, we proposed that anti-CCP
Jacobsen, Søren, Østergaard, Mikkel, Junker, Michael Peter, Lindegaard, Hanne, Ejbjerg, Bo Jannik, JENS K. PEDERSEN, Christensen, Anne F, Pedersen, Jens K, Svendsen, Anders, HENRIK SKJØDT, Pedersen, Jens K; id_orcid, Ostergaard, Mikkel, Pødenphant, Jan, Hansen, Ib, ULRIK TARP, SØREN JACOBSEN, ANDERS SVENDSEN, Junker, Peter, Hansen, Ib Tønder, TINE LOTTENBURGER, HANNE LINDEGAARD, KIM HØRSLEV-PETERSEN, BO EJBJERG, Andersen, Lis S, Ejbjerg, Bo, Skjødt, Henrik, JAN PØDENPHANT, PETER JUNKER, Ellingsen, Torkell Juulsgaad, Hetland, Merete Lund, Hørslev-Petersen, Kim, IB HANSEN, Ellingsen, Torkell Juulsgaad; id_orcid, Stengaard-Pedersen, Kristian, KRISTIAN STENGAARD-PEDERSEN, Lauridsen, Ulrik Birk, MERETE L. HETLAND, Lottenburger, Tine, ULRIK B. LAURIDSEN, Svendsen, Anders; id_orcid, ANNE F. CHRISTENSEN, MIKKEL ØSTERGAARD, Andersen, Lis Abildgaard, LIS S. ANDERSEN, Hetland, Merete L, TORKELL ELLINGSEN, Tarp, Ulrik, Lauridsen, Ulrik B   +47 more
core   +1 more source

Outcomes of Tapering Biologic and Targeted Synthetic Disease‐Modifying Antirheumatic Drugs in Rheumatoid Arthritis: A Multicenter Randomized Noninferiority Trial

Arthritis &Rheumatology, EarlyView.
Objective Evidence supporting tapering of biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) in patients with rheumatoid arthritis (RA) with sustained low disease activity (LDA) remains limited. We evaluated the efficacy and safety of a structured b/tsDMARD‐tapering strategy in patients with RA who had achieved sustained ...
Dong‐Jin Park, Sung‐Eun Choi, Ji‐Hyoun Kang, Jung‐Yoon Choe, Hye‐Soon Lee, So‐Young Bang, Yun‐Hong Cheon, Sang‐Il Lee, Mingyo Kim, Yoon‐Kyoung Sung, Soo‐Kyung Cho, Jae Hyun Jung, Sung Hae Chang, Sung Won Lee, Yeon‐Ah Lee, Seung‐Geun Lee, Hyun‐Sook Kim, Seung‐Ki Kwok, Seung‐Cheol Shim, Shin‐Seok Lee   +19 more
wiley   +1 more source

Abatacept reduces disease activity of rheumatoid arthritis independently of modulating anti-citrullinated peptide antibody production

Immunological Medicine, 2020
Abatacept may exert its clinical effect on rheumatoid arthritis (RA) by suppressing anti-cyclic citrullinated peptide (CCP) antibody production. This study was undertaken to test this hypothesis by examining the changes of disease activity of RA and anti-
Hisakata Yamada, Tomomi Tsuru, Takeshi Otsuka, Masayuki Maekawa, Hiroshi Harada, Takaaki Fukuda, Hiroshi Tsukamoto, Akira Maeyama, Shigeru Yoshizawa, Ken Wada, Yasuharu Nakashima, Eisuke Shono, Seiji Yoshizawa, Hiroshi Jojima, Masakazu Kondo   +14 more
doaj   +1 more source

Anti-cyclic citrullinated peptide antibodies in children with Juvenile Idiopathic Arthritis

Electronic Physician, 2016
Aim: The purpose of present study was to access the prevalence of anti-cyclic citrullinated peptide (anti-CCP) antibodies in children with Juvenile Idiopathic Arthritis (JIA), and to investigate the clinical significance and diagnostic value of the ...
Mohamed Hamooda, Hala Fouad, Nermeen Galal, Nadia Sewelam, Dina Megahed   +4 more
doaj   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Correlation between Anti-CCP Titer and Body Mass Index Score in Rheumatoid Arthritis Patients in Cipto Mangunkusumo Hospital

Indonesian Journal of Rheumatology, 2018
Background: Rheumatoid Arthritis (RA) is a chronic systemic inflammation that attacks and damages joints of upper and lower extremities. RA causes morbidity and disability, hence, affects the quality of life.
Harry Isbagio, Khadijah Fitriah
doaj   +1 more source

Anti-CCP: History and its Usefulness [PDF]

, 2005
Antibodies directed to cyclic citrullinated peptides (anti-CCP) are highly specific for rheumatoid arthritis (RA) and can easily be detected in sera by using commercially available immunoassays.
V. Boeser, W. Klotz, M. Herold, E. Russe   +3 more
core   +1 more source