Results 11 to 20 of about 380 (165)

Anti-Cyclic Citrullinated Peptide Antibody as a Predictor of Rheumathoid Arthritis Complications

Medical Archives, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease, with more frequent occurrence in the female gender, it primarily affects the lining of the synovial joints, and is associated with lower quality of life, inability to work, progressive disability, and all of these patients are more likely to develop other comorbidities.To display the ...
Mekic, Mevludin, Hadzigrahic, Emina
openaire   +3 more sources

Pathogenic Role of Circulating Citrullinated Antigens and Anti-Cyclic Monoclonal Citrullinated Peptide Antibodies in Rheumatoid Arthritis

Frontiers in Immunology, 2021
We examined whether it is possible to directly detect citrullinated antigens in the serum of rheumatoid arthritis (RA) patients using a monoclonal antibody (mAb) designed to be specific for citrullinated peptides. In order to confirm the potential of the
Pureun Won, Pureun Won, Youngkyun Kim, Youngkyun Kim, Youngkyun Kim, Hyerin Jung, Hyerin Jung, Yeri Alice Rim, Yeri Alice Rim, Dong Hyun Sohn, Dong Hyun Sohn, Dong Hyun Sohn, William H. Robinson, William H. Robinson, Su-Jin Moon, Ji Hyeon Ju, Ji Hyeon Ju, Ji Hyeon Ju   +17 more
doaj   +1 more source

Detection of Anti-Vimentin Antibodies in Patients with Sarcoidosis

Diagnostics, 2022
There is a need to further characterize the antibody response to vimentin in relation to its possible involvement in pathogenicity of sarcoidosis and other lung disorders.
Anna Starshinova, Anna Malkova, Ulia Zinchenko, Sergey Lapin, Alexandra Mazing, Dmitry Kudlay, Piotr Yablonskiy, Yehuda Shoenfeld   +7 more
doaj   +1 more source

Rheumatoid arthritis sera antibodies to citrullinated collagen type II bind to joint cartilage

Arthritis Research & Therapy, 2022
Objective To investigate the occurrence and frequency of anti-citrullinated protein antibodies (ACPA) to cyclic citrullinated type II collagen (COL2) epitope with a capacity to bind joint cartilage.
Qixing Li, Yanpeng Li, Bibo Liang, Rui Xu, Bingze Xu, Erik Lönnblom, Hui Feng, Jing’an Bai, Roma Stawikowska, Changrong Ge, Aiping Lu, Gregg B. Fields, Lianbo Xiao, Rikard Holmdahl   +13 more
doaj   +1 more source

Anti-cyclic citrullinated peptide antibody (ACPA) and Rheumatoid arthritis: Clinical relevance [PDF]

Journal of Clinical Orthopaedics and Trauma, 2022
Rheumatoid Arthritis (RA) is the most common auto-immune, chronic inflammatory joint disease. Predominantly a musculoskeletal condition with a wide spectrum of skeletal and extra-skeletal manifestations, RA has a significant footfall in orthopaedic clinical practice worldwide. RA is essentially a clinical diagnosis; however, laboratory and radiographic
Karthikeyan. P. Iyengar, Abhishek Vaish, Arvind Nune   +2 more
openaire   +2 more sources

Anti‐cyclic citrullinated peptide antibodies in type 1 autoimmune hepatitis [PDF]

Alimentary Pharmacology & Therapeutics, 2005
SummaryBackground : Besides the autoantibodies included in the diagnostic criteria of type 1 autoimmune hepatitis, many other autoantibodies have been described in this condition. Recently, antibodies against cyclic citrullinated peptide have been validated as specific diagnostic and prognostic markers of rheumatoid arthritis.Aim : To assess whether ...
M, Fusconi, A, Vannini, A C, Dall'Aglio, G, Pappas, F, Cassani, G, Ballardini, M, Frisoni, A, Grassi, F B, Bianchi, D, Zauli   +9 more
openaire   +2 more sources

Can SARS‐CoV‐2 infection trigger rheumatoid arthritis? A case report

Clinical Case Reports, 2022
Inflammatory arthritis has been reported after SARS‐COV‐2 infection. We present a case of a 38‐year‐old female patient who developed polyarthralgia 1 month after SARS‐COV‐2 infection. Musculoskeletal examination was significant for synovitis of hands and
Sirine Bouzid, Kawther Ben Abdelghani, Saoussen Miledi, Alia Fazaa, Ahmed Laatar   +4 more
doaj   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Abatacept reduces disease activity of rheumatoid arthritis independently of modulating anti-citrullinated peptide antibody production

Immunological Medicine, 2020
Abatacept may exert its clinical effect on rheumatoid arthritis (RA) by suppressing anti-cyclic citrullinated peptide (CCP) antibody production. This study was undertaken to test this hypothesis by examining the changes of disease activity of RA and anti-
Hisakata Yamada, Tomomi Tsuru, Takeshi Otsuka, Masayuki Maekawa, Hiroshi Harada, Takaaki Fukuda, Hiroshi Tsukamoto, Akira Maeyama, Shigeru Yoshizawa, Ken Wada, Yasuharu Nakashima, Eisuke Shono, Seiji Yoshizawa, Hiroshi Jojima, Masakazu Kondo   +14 more
doaj   +1 more source

Knee alterations in rheumatoid arthritis: Comparison of US and MRI

Open Medicine, 2021
This study was designed to compare the diagnostic efficacy of ultrasonography (US) and magnetic resonance imaging (MRI) in detecting changes in the knee of patients with rheumatoid arthritis (RA) and discover the possible association between the ...
Xiao Lu, Huang Yanyan, Zhan Feng
doaj   +1 more source