Results 1 to 10 of about 16,849 (159)

Identification of potential autoantigens in anti-CCP-positive and anti-CCP-negative rheumatoid arthritis using citrulline-specific protein arrays. [PDF]

Sci Rep, 2021
AbstractThe presence or absence of autoantibodies against citrullinated proteins (ACPAs) distinguishes two main groups of rheumatoid arthritis (RA) patients with different etiologies, prognoses, disease severities, and, presumably, disease pathogenesis.
Poulsen TBG, Damgaard D, Jørgensen MM, Senolt L, Blackburn JM, Nielsen CH, Stensballe A.   +6 more
europepmc   +6 more sources

Anti-CCP antibodies and bone. [PDF]

Arthritis Res Ther, 2018
Anti-CCP antibodies and bone.
Orsolini G, Viapiana O, Rossini M, Adami G, Caimmi C, Fassio A, Gatti D.   +6 more
europepmc   +6 more sources

The association of anti-CCP antibodies with disease activity in rheumatoid arthritis [PDF]

Rheumatology International, 2008
Antibodies to citrullinated proteins have been described in patients with rheumatoid arthritis (RA) and these appear to be the most specific markers of the disease. Our objective was to determine the frequency of antibodies to cyclic citrullinated peptides (CCPs) in patients with RA and the association of anti-CCP antibodies with disease activity ...
Sibel Kul, Hasim Cakirbay, Orhan Deger   +2 more
exaly   +3 more sources

Anti-citrullinated protein antibodies in the diagnosis of rheumatoid arthritis (RA): diagnostic performance of automated anti-CCP-2 and anti-CCP-3 antibodies assays. [PDF]

Clin Rheumatol, 2017
This study compares the diagnostic performance of a second generation anti-cyclic citrullinated peptide antibody (CCP2) with a third generation anti-CCP antibodies assay (CCP3), as well as the combination of both tests. Serum samples of 127 patients were analyzed.
Vos I, Van Mol C, Trouw LA, Mahler M, Bakker JA, Van Offel J, De Clerck L, Huizinga TW.   +7 more
europepmc   +6 more sources

Comparison of different assays for the detection of anticyclic citrullinated peptide antibodies in patients with rheumatoid arthritis

Frontiers in Immunology, 2022
ObjectiveTo evaluate a novel fully automated immunoturbidimetric assay developed by Qiangsheng Biotechnology Company for the detection of anticyclic citrullinated peptide antibodies (anti-CCP) in serum of patients with rheumatoid arthritis (RA) and ...
Lisha Ma, Wensheng Wang, Lisha Li, Ying Chen, Binxuan Chen, Miaoli Shao, Yongjun Cheng, Renfang Zhou   +7 more
doaj   +1 more source

Anti‐CCP: History and its Usefulness [PDF]

Journal of Immunology Research, 2005
Antibodies directed to cyclic citrullinated peptides (anti‐CCP) are highly specific for rheumatoid arthritis (RA) and can easily be detected in sera by using commercially available immunoassays. The second version of the anti‐CCP test (anti‐CCP2) demonstrated high specificity (89‐98%) and good sensitivity (41‐88%)
M. Herold, V. Boeser, E. Russe, W. Klotz
openaire   +3 more sources

A retrospective analysis of the relationship between anti-cyclic citrullinated peptide antibody and interstitial lung disease in systemic sclerosis

Scientific Reports, 2022
Anti-cyclic citrullinated peptide antibody testing is used to diagnose rheumatoid arthritis and associated with interstitial lung disease in RA. Herein, we investigate the relationship between anti-CCP antibody and ILD in SSc.
Jang Woo Ha, Yoo Jin Hong, Hyun Jin Cha, Jeonghun Daniel Moon, Jung Yoon Pyo, Sang-Won Lee, Yong-Beom Park, Chul Hwan Park, Jason Jungsik Song   +8 more
doaj   +1 more source

Anti-CCP antibodies: the past, the present and the future [PDF]

Nature Reviews Rheumatology, 2011
Rheumatoid arthritis (RA) is an autoimmune disease characterized by autoantibodies against citrullinated antigens. The importance of citrulline for the epitopes bound by these autoantibodies, referred to as ACPA (anti-citrullinated peptide/protein antibodies), was first described in 1998.
van Venrooij, W.J.W., van Beers, J.J.B.C., Pruijn, G.J.M., Pruijn, G.J.M.   +3 more
openaire   +2 more sources

Immunosensing the rheumatoid arthritis biomarker through bifunctional aldehyde-amine linkers on an iron oxide nanoparticle seeded voltammetry sensor

Nanomaterials and Nanotechnology, 2022
An immunosensor was developed on an interdigitated electrode (IDE) by voltammetry sensing for the early identification of the autoimmune disease ‘rheumatoid arthritis (RA)’ by detecting the biomarker anti-cyclic citrullinated peptide antibody (anti-CCP).
Bowei Zhou, Yonglong Yan, JingBo Xie, Hongbo Huang, Heyun Wang, Subash CB Gopinath, Periasamy Anbu, Sanshan He, Lijun Zhang   +8 more
doaj   +1 more source

Long-term follow-up of patients with anti-cyclic citrullinated peptide antibody-positive connective tissue disease: a retrospective observational study including information on the HLA-DRB1 allele and citrullination dependency

Arthritis Research & Therapy, 2020
Background The anti-cyclic citrullinated peptide (CCP) antibody is a diagnostic biomarker of rheumatoid arthritis (RA). However, some non-RA connective tissue disease (CTD) patients also test positive for the anti-CCP antibody and, thus, may ultimately ...
Takeshi Iwasaki, Shuichiro Nakabo, Chikashi Terao, Kosaku Murakami, Ran Nakashima, Motomu Hashimoto, Yoshitaka Imura, Naoichiro Yukawa, Hajime Yoshifuji, Yasuo Miura, Kimiko Yurugi, Taira Maekawa, Myrthe A. M. van Delft, Leendert A. Trouw, Takao Fujii, Tsuneyo Mimori, Koichiro Ohmura   +16 more
doaj   +1 more source