Results 61 to 70 of about 3,099,905 (215)

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Anti Citrullinated Protein / Peptide Antibody Assay, Rheumathoid Factor or Both as Shifted Test in Diagnostic and Prognostic Evaluation in Patients with Rheumathoid Arthritis [PDF]

, 2014
The aim of this study was to compare the diagnostic values of laboratory variables, to present quantitative evaluations of the anti citrullinated protein / peptide antibody (ACPA), or anti CCP ( anti-cyclic citrullinated peptide, anti-CCP 2) antibodies ...
Krstevska Balkanov, Svetlana, Sotirova, Tatjana, Genadieva Stavrik, Sonja, Spasovski, Dejan, Alabakovska, Sonja, Balkanov, Trajan, Slaninka Micevska, Maja   +6 more
core   +2 more sources

Lung Ultrasound for the Detection of Radiologic Progression of Interstitial Lung Abnormalities in Patients With Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Interstitial lung disease (ILD) is an important extra‐articular manifestation of rheumatoid arthritis (RA) associated with high mortality and morbidity. Lung ultrasonography (LUS) has recently emerged as a possible screening tool. We assessed the role of LUS in monitoring radiologic progression and the development of new interstitial lung ...
Marie Vermant, Valerie Van Ballaer, Joseph Jacob, Tine Follet, Ryoko Egashira, Kenny Anseele, Heleen Cypers, Laurens J. De Sadeleer, Nico De Crem, Tinne Goos, Barbara Neerinckx, Veerle Taelman, Nathalie Veyt, Alexandros Kalkanis, Patrick Verschueren, Wim A. Wuyts   +15 more
wiley   +1 more source

Dislipidemia na artrite reumatoide e sua associação com parâmetros clinicos e laboratorias [PDF]

, 2011
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Batista, Greice Suellen
core  

Anti-cyclic Citrullinated Peptide Antibodies in Patients with Juvenile Idiopathic Arthritis

Autoimmunity, 2002
We analysed the presence of anti-cyclic citrullinated peptide (anti-CCP) and anti-keratin (AKA) antibodies of the IgG class in sera of patients with defined juvenile idiopathic arthritis (JIA) of various subgroups with more than one year duration of the disease.
Ilona, Hromadnikova, Katerina, Stechova, Vavrincova, Pavla, Dana, Hridelova, Bela, Houbova, Sona, Voslarova, Hana, Nekvasilova, Jan, Vavrinec   +7 more
openaire   +2 more sources

Machine Learning to Predict Remission Between 6 and 24 Months in Rheumatoid Arthritis: Insights From JAK, an International Registry Collaboration

Arthritis &Rheumatology, EarlyView.
Objective To develop, externally validate, and simplify a machine learning model to predict remission between 6 and 24 months in patients with rheumatoid arthritis (RA) initiating tumor necrosis factor inhibitors, JAK inhibitors, interleukin‐6 inhibitors, abatacept, or rituximab using data from 11 international registries in the JAK‐pot collaboration ...
Zubeyir Salis, Denis Mongin, Denis Choquette, Louis Coupal, Catalin Codreanu, Florenzo Iannone, Roberto Caporali, Tore K. Kvien, Sella Provan, Ruth Fritsch‐Stork, Dan Nordström, Nina Trokovic, Karel Pavelka, Jakub Závada, Ana Rodrigues, Ziga Rotar, Prodromos Sidiropoulos, Irini Flouri, Céline Lamacchia, Michele Iudici, Delphine Courvoisier, Kim Lauper, Axel Finckh   +22 more
wiley   +1 more source

Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities

, 2011
Objective Anti-citrullinated protein antibodies (ACPA) and anti-cyclic citrullinated peptide (anti-CCP) antibodies are a hallmark of rheumatoid arthritis and are believed to play a role in disease pathogenesis.
Ioan-Facsinay, A., Menard, H.A., Trouw, L.A., Huizinga, T.W.J., Bannoudi, H. el, Scherer, H.U., Lora, M., Woude, D. van der, Toes, R.E.M.   +8 more
core   +1 more source

Expression and diagnostic utility of anti-cyclic citrullinated peptide antibodies in juvenile idiopathic arthritis [PDF]

, 2015
Background: Juvenile idiopathic arthritis (JIA) is a clinically heterogeneous group of arthritis occurring in children. Anti-cyclic citrullinated peptide (anti-CCP) antibodies have been recently included in the revised diagnostic criteria for adult onset
Afify, MF, El Laban, AS, Sayed, AO
core   +1 more source

The Association of Anti-Aminoacyl-Transfer Ribonucleic Acid Synthetase Antibodies in Patients With Rheumatoid Arthritis and Interstitial Lung Disease

The Turkish Journal of Gastroenterology, 2018
Objectives: This study aims to analyze the distribution and clinicopathological characteristics of anti-aminoacyl-transfer ribonucleic acid (tRNA) synthetase (ARS) antibodies in rheumatoid arthritis patients.
Masakazu MATSUSHITA, Naoto TAMURA, Michihiro OGASAWARA, Kurisu TADA, Ken YAMAJI, Yoshinari TAKASAKI   +5 more
doaj  

Anti-Citrullinated Protein Antibody Titers Are Independently Modulated by Both Disease Activity and Conventional or Biologic Anti-Rheumatic Drugs

Diagnostics, 2022
This study aimed to analyze the factors that influence anti-citrullinated protein antibody (ACPA) titers in a seropositive early arthritis (EA) population under non-protocolized treatment with disease-modifying anti-rheumatic drugs (DMARDs).
Miren Uriarte Ecenarro, Daniel Useros, Aranzazu Alfranca, Reyes Tejedor, Isidoro González-Alvaro, Rosario García-Vicuña   +5 more
doaj   +1 more source