Results 131 to 140 of about 140,143 (264)

Qualified prediction system for allograft failure in real world settings: extended validation study. [PDF]

BMJ Med
Raynaud M, Truchot A, Naser S, Aubert O, Divard G, Thalamas T, Lombardi Y, Legendre C, Bailly E, Buchler M, Crespo M, Redondo D, Astor BC, Mandelbrot D, Parajuli S, Juric I, Basic-Jukic N, Helanterä I, Evans RDR, Sanghera A, Javed M, Molnar MZ, Yamauchi J, Fornadi K, Linhares K, Baujard M, Fowler KJ, Akalin E, Gupta G, Soler Pujol G, Tedesco-Silva H, Orandi BJ, Naesens M, Budde K, Naik M, Hertig A, Anglicheau D, Kamar N, Segev DL, Lefaucheur C, Loupy A.   +40 more
europepmc   +1 more source

Liver Endothelia Orchestrate MASH‐Associated Macrophage Zonation Through FSTL1‐ITGA4 Axis

Advanced Science, EarlyView.
Liver inflammation in MASH fundamentally hinges on the newly defined Kit/STAT2/FSTL1/ITGA4 axis. Declining endothelial Kit collapses normal hepatic zonation, driving an aberrant FSTL1 gradient that recruits pathogenic macrophages. Strikingly, targeting FSTL1‐ITGA4 with anti‐VLA4 restores spatial immune homeostasis and halts disease progression ...
Lin Sun, Zhensheng Yue, Zhiqiang Fang, Hao Xu, Wei Du, Yuwei Ling, Jingjing Liu, Ping Song, Fei He, Juanli Duan, Lin Wang   +10 more
wiley   +1 more source

Racial Discrimination and Hwa-byung, a Korean Medicine-Based Anger Syndrome, among Foreign Residents in South Korea: a cross-sectional study. [PDF]

J Pharmacopuncture
Kwon CY.
europepmc   +1 more source

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Anti-Asian Racism: Developing a Brief, Reliable, and Valid Measure. [PDF]

J Racial Ethn Health Disparities
Lee DB, Yang X, Wu TY, Mouacheupao I, Zimmerman MA, Hsieh HF.   +5 more
europepmc   +1 more source

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

Stigma, culture, and mental health help-seeking among Black African immigrants in the United States: an integrative literature review. [PDF]

Cogent Ment Health
Ashu ANT.
europepmc   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

Advanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang, Fen Xiong, Yiwen Peng, Lingfei Meng, Xinran Wang, Yingruo Xu, Tian Tang, Hongchang Gao   +7 more
wiley   +1 more source

The racial trauma task force: Clinical-community psychology approaches to healing racial trauma during COVID-19. [PDF]

Am J Community Psychol
Metzger IW, Adams SJ, Smith K, La Barrie DL, Surprenant B, Bartolomeo LA, Rea K, Nguyen J, Brown J, Brown C, Rodriguez VJ.   +10 more
europepmc   +1 more source