Results 211 to 220 of about 196,853 (312)

Implicit bias attribution reduces prosocial emotions and donation intentions for natural disaster victims. [PDF]

Commun Psychol
Bak H, Kazakoglu G, Sulaiman S, Richeson JA.   +3 more
europepmc   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

The Longitudinal Association Between Experiences of Racial and Ethnic Discrimination and Mental Health Outcomes Among Latine Adolescents in an Agricultural Community. [PDF]

J Adolesc Health
Bhushan NL, Stoner MCD, Browne EN, Shapley-Quinn MK, Jaime-Aguilar A, Raymond-Flesch M, Minnis AM.   +6 more
europepmc   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source

Formative Research to Identify Contributors to Risky Drinking and Adapt an Alcohol Reduction Intervention Among Young Adults Vulnerable to HIV: Qualitative Focus Group Study. [PDF]

JMIR Form Res
Sesenu F, Kirklewski S, Takenaka B, Brown J, Nicholson E, Haney K, Carroll K, Restar A, Boyd DT, Fallin-Bennett K, Kershaw T, Lauckner C.   +11 more
europepmc   +1 more source

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source

Urinary transcription factor 21 (TCF21) as a non-invasive biomarker of podocyte injury in preeclampsia: diagnostic performance and translational insights from a case-control study. [PDF]

BMC Pregnancy Childbirth
Keryakos HKH, Youssuf AM, El-Ela MA, Abo-Ellil NEMM.   +3 more
europepmc   +1 more source

The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus

Advanced Science, EarlyView.
BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang, Zijin Liu, Minshan Jin, Junting Liu, Shihao Wei, Dengmao Yang, Saiqi Yang, Yuan Guo, Mingxun Chen   +8 more
wiley   +1 more source

Breaking the stigma: the role of family support in hepatitis B management from a public health education perspective. [PDF]

Front Public Health
Zhang L, Chen J, Wu G, Pang S, Zhang Z, Yan Y.   +5 more
europepmc   +1 more source

EEOC, Christopher, Bhend, and Chamara v. National Education Association, National Education Association - Alaska [PDF]

, 2006
Singleton, Judge James K.
core   +1 more source