Results 101 to 110 of about 7,906 (281)

Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal, Sangeeta Yadav, Akash Kumar, Tanbeer Kaur, Yashna Bawa, Sarvesh Rustagi, Rahul Mehra   +6 more
wiley   +1 more source

Addition of 3-day aprepitant to ondansetron and dexamethasone for prophylaxis of chemotherapy-induced nausea and vomiting among patients with diffuse large B cell lymphoma receiving 5-day cisplatin-based chemotherapy

Journal of the Egyptian National Cancer Institute, 2017
Background: Neurokinin-1 receptor antagonists, such as aprepitant are currently emerging as powerful prophylactic agents for chemotherapy-induced nausea and vomiting (CINV).
Raafat Abdel-Malek, Noha Abbas, Kyrillus S. Shohdy, Mohamed Ismail, Radwa Fawzy, Dalal S. Salem, Ezzat Safwat   +6 more
doaj   +1 more source

Effect of Prophylactic Anti-emetics on Opioid-induced Nausea and Vomiting: A Retrospective Observational Cohort Study. [PDF]

In Vivo, 2021
Tamura T, Kawakado K, Makimoto GO, Nakanishi M, Kuyama S.   +4 more
europepmc   +1 more source

Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972 [PDF]

, 2003
BACKGROUND: Oligodendroglial tumors are chemosensitive, with two-thirds of patients responding to PCV combination chemotherapy with procarbazine, lomustine (CCNU) and vincristine.
Baron, B., Bent, M.J. (Martin) van den, Beule, N. de, Boogerd, W. (Willem), Bravo Marques, J., Chinot, O., Kros, J.M. (Johan), Rijt, C.C.D. (Carin) van der, Taphoorn, M.J. (Martin), Vecht, C.J.   +9 more
core  

Non‐Syndromic Tumefactive Demyelinating Lesions in the Pediatric Population: Four Case Reports and Review of the Literature

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction Tumefactive demyelinating lesions (TDLs) are large lesions (> 2 cm) seen in demyelinating syndromes such as multiple sclerosis, myelin oligodendrocyte glycoprotein antibody‐associated disorder, and neuromyelitis optica spectrum disorder. They rarely occur in children and most often have a monophasic course.
Elizabeth C. Ballinger, Hannah F. Todd, Jonathan M. Yarimi, Timothy E. Lotze, Nikita M. Shukla, Kristen S. Fisher, Alexander J. Sandweiss   +6 more
wiley   +1 more source

Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration [PDF]

, 2014
Cisplatin is a highly emetogenic cancer chemotherapy agent, which is often used to induce nausea and emesis in animal models. The cytotoxic properties of cisplatin also cause adverse events that negatively impact on animal welfare preventing repeated ...
A Tidholm, BD Rose, CC Horn, CL Limebeer, DC Dale, DM Vail, E Portillo, EM Rock, G Jang, GK Ogilvie, GK Ogilvie, GP Chrousos, GR Morrow, H Imamura, Hannah Kenward, IK Vonderen van, J Ito, J Loor, JD Chen, Jonathan Elliott, K Barabas, K Olsson, KL Koch, L Kelland, LA Parker, LA Parker, Ludovic Pelligand, LX Cubeddu, LX Cubeddu, M Boer-Dennert de, M Fredrikson, M Minami, MK Samson, MS Kim, N Percie du Sert, N Percie du Sert, PL Andrews, PL Andrews, PL Andrews, RD Fisher, S Ina, S Robery, SD Caras, T Bloom, V Napadow, VA Puente-Redondo de la, X Yu   +46 more
core   +3 more sources

Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed‐Dose Combination Tablets in Healthy Chinese Volunteers

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye, Rui Zhang, Jing Wan, Jinping Zhou, Pengpeng Guo, Dianwen Yu, Peixia Li, Yani Liu, Shaojun Shi   +8 more
wiley   +1 more source

Phase II study of dacarbazine given with modern prophylactic anti-emetics and growth factor support to patients with metastatic, resistant soft tissue, and bone sarcoma. [PDF]

Rare Tumors, 2021
Van Tine BA, Weiss MC, Hirbe AC, Oppelt PJ, Abaricia S, Trinkaus K, Luo J, Berry S, Ruff T, Callahan C, Toensikoetter J, Ley J, Siegel MJ, Dehdashti F, Siegel BA, Adkins DR.   +15 more
europepmc   +1 more source

Use of drug therapy in the management of symptomatic ureteric stones in hospitalized adults (SUSPEND), a multicentre, placebo-controlled, randomized trial of a calcium-channel blocker (nifedipine) and an α-blocker (tamsulosin) : study protocol for a randomized controlled trial [PDF]

, 2014
Peer reviewedPublisher ...
Anson, Ken, Burr, Jennifer, Kilonzo, Mary, Lam, Thomas, MacLennan, Graeme Stewart, McClinton, Sam, McDonald, Alison, McPherson, Gladys, N'Dow, James, Pickard, Robert, Starr, Kathryn, SUSPEND Study Group, Thomas, Ruth   +12 more
core   +2 more sources

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source