Results 91 to 100 of about 7,850 (302)

Pregnancy, prescription medicines and the potential risk of herb-drug interactions:a cross-sectional survey [PDF]

, 2017
Funding All funding was from institutional resource. JSM, AS are employed by the University of Aberdeen. DS is employed by the Robert Gordon University. BP and CR are employed by NHS Scotland.
A Fugh-Berman, A Lupattelli, A Smeriglio, A Steel, A Vickers, AA Izzo, AA Mitchell, Abdul R. Pallivalapila, AR Pallivalapila, AR Pallivalapilla, AR Pallivalapilla, Ashalatha Shetty, Binita Pande, CH Chuang, Craig Rore, DA Forster, DA Kennedy, Derek Stewart, E Ernst, F Facchinetti, GG Briggs, H Nordeng, H Nordeng, HG Hall, J Adams, J Boivin, J Henderson, James S. McLay, JJ Dugoua, JR Daw, K Moussally, K Moussally, KJ Hunt, KM Kuczkowski, L Cuzzolin, L Holst, M Elvin-Lewis, M Tabatabaee, MC Mothupi, ME Palmer, Moza Al Hail, Naila Izzati, O Stephansson, P Posadzki, RE Graham, RE Westfall, RJ Ko, S Eardley, TC Clarke, W Abebe   +49 more
core   +4 more sources

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

NEPA, a new fixed combination of netupitant and palonosetron, is a cost-effective intervention for the prevention of chemotherapy-induced nausea and vomiting in the UK [PDF]

, 2017
Background: The objective was to evaluate the cost-effectiveness of NEPA, an oral fixed combination netupitant (NETU, 300 mg) and palonosetron (PA, 0.5 mg) compared with aprepitant and palonosetron (APPA) or palonosetron (PA) alone, to prevent ...
Bourhis, Francois, Cawston, Helene, Di'Agostino, Paolo, Eriksson, Jennifer, McGuire, Alistair, Ruffo, Pierfrancesco, Schwartzberg, Lee, Turini, Marco   +7 more
core   +3 more sources

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Insidious onset of Pisa syndrome after rasagiline therapy in a patient with Parkinson’s disease [PDF]

, 2014
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COSENTINO, Giuseppe, D'AMELIO, Marco, FIERRO, Brigida, MASTRILLI, Sergio, REALMUTO, Sabrina, SAVETTIERI, Giovanni, VALENTINO, Francesca   +6 more
core   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

N,N'-1,2-Phenylenebis[4-(chloromethyl)benzamide] [PDF]

, 2010
4 páginas, 1 esquema.-- This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.N,N'-1,2-Phenylenebis[4-(chloromethyl)benzamide] (3) was obtained in 61% yield by nucleophilic acyl ...
Bachl, Jürgen, Díaz Díaz, David
core   +2 more sources

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Effect of rofecoxib on platelet aggregation and blood loss in gynaecological and breast surgery compared with diclofenac [PDF]

, 2017
Background. Non‐selective cyclooxygenase (COX) inhibitors or non‐steroidal anti‐ inflammatory drugs (NSAIDs) are frequently omitted for perioperative pain relief because of potential side‐effects.
Baumann, P. C., Bombeli, T., Haller, U., Hegi, T. R., Pasch, T., Seifert, B., Spahn, D. R., Zalunardo, M. P.   +7 more
core  

Use of antiemetics in early pregnancy 2012–2022: A cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
Aim Nausea and vomiting in pregnancy impact quality of life, yet many pregnant women feel dismissed by healthcare professionals, despite the safety of first‐line antiemetic treatments for both mother and fetus. Therefore, this study aims to describe the prevalence of patient‐reported antiemetic use in early pregnancy in Copenhagen, Denmark, the changes
Katrine Bak Wraae, Nanna Roed Ballegaard, Mie Lærkeholm Hede, Line Buchgreitz, Ane Lilleøre Rom, Hanne Kristine Hegaard, Nina Olsén Nathan   +6 more
wiley   +1 more source