Results 191 to 200 of about 7,805 (301)

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Association Between Discharge Medications and Oncologic Post-Embolization-Syndrome-Related Outcomes. [PDF]

Cancer Med
Li H, Moon J, Sim N, Horný M, Lima N, Konstantinidis M, Iyer D, Benenati S, Gichoya J, Newsome J, Bercu Z.   +10 more
europepmc   +1 more source

Rare but relevant: Ibogaine and cardiovascular complications—prolonged QT interval and ventricular arrhythmias

Addiction, EarlyView.
Abstract Revived interest in psychedelic‐assisted therapies has also renewed focus on ibogaine, a psychoactive alkaloid, for its notable anti‐addictive potential. Evidence from observational, open‐label, and limited randomized placebo‐controlled trials indicates that ibogaine and its metabolite noribogaine reduce craving and withdrawal symptoms in ...
Tibor Markus Brunt
wiley   +1 more source

Vestibular Suppressant Utilization and Subsequent Falls Among Patients 65 Years and Older With Dizziness in the United States. [PDF]

J Am Geriatr Soc
Marmor S, Karaca-Mandic P, Adams ME.
europepmc   +1 more source

Tissue‐retained needles in people who inject drugs: A systematic review of case reports and series on clinical presentations, complications and management

Addiction, EarlyView.
Abstract Background and aims Tissue‐retained needles from intravenous drug use can cause rare but severe complications, ranging from local to systemic infections to needle embolization. Due to the limited evidence and the lack of epidemiological studies on the issue, we systematically reviewed the literature focusing on case reports and case series on ...
Heidi Laukkala, Anna Nevalainen, Irina Rinta‐Kiikka, Samuel Heikkilä, Sisu Kiuru, Markku Sumanen, Otso Arponen, Olli Nevalainen   +7 more
wiley   +1 more source

Gastrointestinal Symptoms in Obesity Therapy: Mechanisms, Epidemiology, and Management Strategies. [PDF]

Biomedicines
Witaszek T, Biesiada A, Iskra-Trifunović J, Babicki M, Mastalerz-Migas A, Kłoda K.   +5 more
europepmc   +1 more source

New directions for anti-emetic research

Annals of Oncology, 1994
openaire   +2 more sources

Personalized Cancer Vaccines in the Clinical Trial Pipeline

Asia-Pacific Journal of Clinical Oncology, EarlyView.
This study analyzes the current landscape of personalized cancer vaccine clinical trials, highlighting trends in vaccine platforms, trial phases, and geographic distribution. Peptide and dendritic cell vaccines dominate early‐stage research, with promising immune responses observed in melanoma, glioblastoma, and urothelial cancer trials.
Liudmila Iamukova, Elena Alferova
wiley   +1 more source

Trastuzumab Deruxtecan for HER2‐Low Metastatic Breast Cancer: Practical Considerations for Medical Oncologists and Pathologists in Australia

Asia-Pacific Journal of Clinical Oncology, EarlyView.
ABSTRACT Trastuzumab deruxtecan (T‐DXd) is a third‐generation, HER2‐targeting antibody‐drug conjugate that has been shown to significantly prolong overall survival, compared with standard chemotherapy, when used to treat patients who have “HER2‐low” (HER2 immunohistochemistry [IHC] score 1+; or HER2 IHC 2+ plus in situ hybridization‐negative ...
Andrew Redfern, Elgene Lim, Sunil Lakhani, Nirmala Pathmanathan, Sudarsha Selva‐Nayagam, Nicole McCarthy, Belinda Yeo, Benjamin Dessauvagie, Gelareh Farshid   +8 more
wiley   +1 more source

Monoclonal Antibody Therapies in Alzheimer's Disease: A Guide for Emergency Physicians. [PDF]

Emerg Med Australas
Wrigley S, Huynh ALH, Amadoru S, Zeimer H, Tan I, Woodward M, Braitberg G, Yates PA.   +7 more
europepmc   +1 more source