This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He +10 more
wiley +1 more source
Confronting Europe's toxics trade from below: the contested global legacy of the 1976 Seveso disaster. [PDF]
van Zon K.
europepmc +1 more source
Politicizing Social Inequality: Competing Narratives From the Alternative for Germany and Left-Wing Movement Stand Up. [PDF]
Schmidtke O.
europepmc +1 more source
The pernicious whiteness of coloniality in elementary science classrooms: the multigenerationality of subtractive schooling in El Sur de Tejas, Aztlán. [PDF]
Luna NA, Jupp JC.
europepmc +1 more source
Electrolyte Additive Strategies in Aqueous Zn‐Ion Batteries: Recent Advances and Prospects
This article provides a comprehensive overview of the current status and future development directions of AZIBs electrolyte additives in three aspects: stabilizing zinc anodes (uniform deposition, inhibition of dendritic crystals), protecting cathodes (structural stability, inhibition of dissolution), and enhancing electrolyte stability (wider ...
Yuanze Yu +7 more
wiley +1 more source
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Gerbils without Borders: Invasiveness, Plague, and Micro-Global Histories of Science, 1932-1939. [PDF]
Skotnes-Brown J, da Silva MAD.
europepmc +1 more source
'To Cleanse the Countryside We Must First Cleanse Hearts': The Culture of Rural Pacification in Japanese-occupied China. [PDF]
Taylor JE.
europepmc +1 more source
Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu +13 more
wiley +1 more source

