Results 51 to 60 of about 2,385,197 (304)

Anti-Ssb/La Antibody Is Negatively Associated with Hla-Dr2 in Chronic Hepatitis C Infection

, 2009
Hepatitis C virus (HCV) infection is frequently associated with anti-SSA/ Ro and anti-SSB/La autoantibodies. The objective of this study is to examine the prevalence of anti -SSA/Ro and anti-SSB/La autoantibodies in HCV-infected patients and their ...
吳建陞;胡忠怡;許秉寧, WU, CHIEN-SHENG;HU, CHUNG-YI;HSU, PING- NING   +1 more
core   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Hidden Patterns of Anti-HLA Class I Alloreactivity Revealed Through Machine Learning

Frontiers in Immunology, 2021
Detection of alloreactive anti-HLA antibodies is a frequent and mandatory test before and after organ transplantation to determine the antigenic targets of the antibodies.
Angeliki G. Vittoraki, Asimina Fylaktou, Katerina Tarassi, Zafeiris Tsinaris, Alexandra Siorenta, George Ch. Petasis, Demetris Gerogiannis, Claudia Lehmann, Maryvonnick Carmagnat, Ilias Doxiadis, Aliki G. Iniotaki, Ioannis Theodorou, Ioannis Theodorou   +12 more
doaj   +1 more source

DataSheet_1_Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance.docx

, 2021
Infusion of regulatory T cells (Tregs) engineered with a chimeric antigen receptor (CAR) targeting donor-derived human leukocyte antigen (HLA) is a promising strategy to promote transplant tolerance.
Anupurna M. Kaul (11454421), Vinh Nguyen (335046), Leonardo M. R. Ferreira (10349225), Kevin K. Leung (9436298), Yannick D. Muller (10349222), Frans H. J. Claas (8465889), Karim Lee (10993371), Gaetano Faleo (1579678), Emilie Ronin (7577873), Arend Mulder (66211), Qizhi Tang (1579672), Nikolaos Skartsis (11454418), Jeffrey A. Bluestone (7541864), James A. Wells (1503346), Patrick Ho (4040531), Yu Zhou (89766)   +15 more
core   +1 more source

Short‐Term Response to Biologic Therapy in Psoriatic Arthritis Is Not Influenced by Disease Duration at Initiation of Therapy

Arthritis Care &Research, EarlyView.
Objective We aimed to determine whether the short‐term response to biologics in biologic‐naive psoriatic arthritis (PsA) is better in patients initiating biologic treatment early in the disease course. Methods Patients with PsA who started on biologic therapy from the year 2000 to 2025 were included for analysis.
Sung Min Cho, Shangyi Gao, Daniel Pereira, Richard J. Cook, Dafna D. Gladman   +4 more
wiley   +1 more source

Effect Modification of Cigarette Smoking on the Relationship Between Posttraumatic Stress Disorder, Other Mental Health Conditions, and Rheumatoid Arthritis Risk: A Large Case‐Control Study in US Veterans

Arthritis Care &Research, EarlyView.
Objective We examined associations of posttraumatic stress disorder (PTSD) and other mental health disorders (OMH) with rheumatoid arthritis (RA), accounting for effects of smoking. Methods We conducted a matched case‐control study, identifying incident RA cases and controls using national Veterans Health Administration data (2006–2019).
Kelsey Coziahr, Harlan Sayles, Tate M. Johnson, Joshua F. Baker, Punyasha Roul, Grant W. Cannon, Gary A. Kunkel, Katherine D. Wysham, Gail S. Kerr, Amir A. Razmjou, Isaac Smith, Jennifer L. Barton, Maria I. Danila, Jonathan S. Richards, Bryant R. England, Ted R. Mikuls   +15 more
wiley   +1 more source

Establishment of Anti-HLA Antibodies in the Sera of Multiparous Pregnant

Eurasian Journal of Medicine, 2019
Objective: It is well known that anti-HLA(Human leucocyte antigen) antibodies have great importance for tissue transplantation. These antibodies were first established in the serum of several blood transfused patients.
Nilnur Eyerci, Gönül Zişan Öncel, Metin İngeç, Atilla Topçu, İbrahim Pirim   +4 more
doaj  

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

HLA B subtype analysis in patients developing tuberculosis during anti-TNF treatment

Scientific Reports
In this study, we aimed to evaluate HLA-B subtypes in cases developing TB while using anti-TNF agents and to compare with the HLA-B subtypes of three different groups including community-acquired TB cases, anti-TNF patients without TB and healthy ...
Fatih Albayrak, Gökhan Keser, Serdar Oztuzcu, Belkıs Nihan Coşkun, Yavuz Pehlivan, Tuba Demirci Yıldırım, Gökçe Kenar Artın, Gözde Çetin Yıldırım, Bünyamin Kısacık   +8 more
doaj   +1 more source

Determination of the PRA Positivity Percentage in Male Patients with Chronic Kidney Disease by Using Flow Cytometry Technique

Acta Clinica Croatica, 2023
The antibodies directed against human leukocyte antigen (HLA) molecules, which play a crucial role in allograft histocompatibility, are called anti-HLA antibodies.
Fatma Avcı Merdin, Hüseyin Koçak, Sadi Köksoy   +2 more
doaj   +1 more source