Results 81 to 90 of about 3,019,129 (340)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Numerical modeling of runback water on ice protected aircraft surfaces [PDF]
A numerical simulation for 'running wet' aircraft anti-icing systems is developed. The model includes breakup of the water film, which exists in regions of direct impingement, into individual rivulets.
Al-Khalil, Kamel M. +2 more
core +1 more source
Environmentally friendly anti-icing [PDF]
, 1998 The present invention describes an aqueous, non-electrolytic, non-toxic, biodegradable, continuous single phase liquid anti-icing or deicing composition for use on the surfaces of, for example, aircraft, airport pavements, roadways, walkways, bridges ...
Haslim, Leonard A. +2 more
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Numerical Modeling of Anti-icing Systems and Comparison to Test Results on a NACA 0012 Airfoil [PDF]
A series of experimental tests were conducted in the NASA Lewis IRT on an electro-thermally heated NACA 0012 airfoil. Quantitative comparisons between the experimental results and those predicted by a computer simulation code were made to assess the ...
Al-Khalil, Kamel M., Potapczuk, Mark G.
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Technical evaluation report, AGARD Fluid Dynamics Panel Symposium on Effects of Adverse Weather on Aerodynamics [PDF]
The purpose of the meeting on Effects of Adverse Weather on Aerodynamics was to provide an update of the stae-of-the-art with respect to the prediction, simulation, and measurement of the effects of icing, anti-icing fluids, and various precipitation on ...
Reinmann, J. J.
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Icing Characteristics and Anti-Icing Heat Requirements for Hollow and Ternally Modified Gas-Heated Inlet Guide Vanes [PDF]
A two-dimensional inlet-guide-vane cascade was investigated to determine the effects of ice formations on the pressure losses across the guide vanes and to evaluate the heated gas flow and temperature required to prevent Icing at various conditions.
Bowden, Dean T., Gray, Vernon H.
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Inside Magazine, December 2009 [PDF]
, 2009 Iowa Department of Transportation Newsletter. INSIDE Magazine is developed to help keep all Iowa DOT employees informed about critical issues affecting them, recognize DOT employees for their excellent service and share interesting aspects in the lives ...
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