Results 101 to 110 of about 65,156 (262)
Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma
Allergy, EarlyView.Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...Cong Dong, Shaohua Lu, Zhenan Deng, Xuliang Cai, Huahao Shen, Guochao Shi, Changxing Ou, Zuofu Peng, Wei Jiang, Xiuhua Fu, Changzheng Wang, Meiling Jin, Zhongmin Qiu, Xiaoyang Wei, Wei Gu, Kewu Huang, Qiang Li, Xiangyan Zhang, Nanshan Zhong, Kian Fan Chung, Qingling Zhang, on behalf of C‐BIOPRED Consortium, Jiangtao Lin, Yongming Zhang, Nan Su, Xiaoyan Zhang, Qing Zhao, Ying Nong, Ping Chen, Tianyi Zhu, Binbin Ji, Yan Wang, Haitao Zhao, Jinbao Wang, Zhiyuan Zhang, Xiaona Yang, Chunhua Wei, Jing Han, Nong Yu, Qiang Li, Zhifu Yang, Yanhong Liu, Guohua Li, Huadong Guan, Shuping Zhang, Xiuhua Fu, Lihong Wang, Lingxin Meng, Zhenting Sun, Guangqin Cao, Lei Zhao, Kewu Huang, Hong Zhang, Wen Wang, Li An, Yangyu Chen, Yanli Gao, Xiaoxia Liu, Huifen Zhai, Fang Lin, Zhaohui Zhong, Zhongguang Wen, Yan Xiao, Jian Kang, Linfei Kong, Xinming Su, Xue Yan, Dijia Zhou, Huaping Tang, Wei Han, Yi Shu, Tintian Li, Lixin Xie, Hong Hu, Bo Liu, Yuzhu Li, Longmei Fan, Yue Zhang, Shifeng Zhao, Xiaofang Liu, Yuhong Wang, Xichun Zhang, Xinmao Wang, Pen Bai, Guangfa Wang, Yan Hu, Zhanwei Hu, Ju Cao, Bei He, Rui Wu, Xiaoyan Gai, Hong Zhu, Zhihai Han, Jiyi Meng, Wei Chen, Li Ma, Zhenqian Liu, Chunyang Zhang, Yan Zhang, Huahao Shen, Fugui Yan, Bin Shen, Xinghong Wang, Hao Zhang, Yinghua Yin, Jinkai Liu, Yanxiong Mao, Mao Huang, Xin Yao, Mao Huang, Ji Zhou, Zhenzhen Wu, Ping Yan, Yujie Zhang, Xinling Yang, Ningfei Ji, Fan Fei, Wanzhen Fu, Yi Yang, Yuting Shi, Wangjian Cha, Guochao Shi, Min Zhou, Wei Tang, Wei Chen, Jun Zhou, Wenjie Yang, Lei Zhu, Meiling Jin, Liping Xue, Li Li, Chun Li, Yin Gong, Qiang Li, Guogang Xie, Luhong Bao, Wuping Bao, Nianyun Li, Fengming Ding, Min Zhang, Zhongmin Qiu, Li Yu, Jungang Xie, Lingling Yi, Xianghuai Xu, Qiang Chen, Junjun Tang, Jinfu Xu, Xiaobing Ji, Jingyun Shi, Bo Su, Xiaojun Yang, Jiuwen Bai, Shuo Liang, Kebing Cheng, Wei Gu, Jiyong Ma, Yun Liu, Jun Ren, Shan Mao, Qingling Zhang, Baoqing Sun, Jiaxing Xie, Rihuang Qiu, Zhiqiang Wang, Peiyan Zhen, Wenting Luo, Changgao Zhong, Wei Luo, Yanqing Xie, Xinxin Yu, Wenting Yu, Wei He, Changzheng Wang, Qianli Ma, Min Wan, Mingzhou Zhang, Haining Li, Shaoxi Cai, Haijin Zhao, Yanmei Ye, Fang Zhou, Laiyu Liu, Guohua Huang, Jianpeng Liang, Jianping Zhao, Jungang Xie, Qiongjie Hu, Kaiyan Li, Wang Ni, Guohua Zheng, Weining Xiong, Lingling Yi, Xihu Du, Yunhui Zhang, Zhi Li, Xiaoqiong Tan, Feng Liao, Shenglan Wang, Yijiang Huang, Xinjun Cai, Kai Liu, Shaojing Sheng, Yihui Fu, Shenghua Sun, Qiang Zhang, Jinweng Cai, Ye Ling, Pin Chen, Hong Luo, Lv Liu, Zhijun Liu, Yuling Tang, Yusheng Yan, Guiyan Mo, Long Wen, Yinqun Zhu, Du Fan +217 morewiley +1 more sourceInternational Evidence‐Based Guidelines for Traditional Chinese Medicine Management of Allergic Rhinitis
Allergy, EarlyView.ABSTRACT
Allergic rhinitis (AR) is a prevalent chronic condition that significantly impacts patients' quality of life and poses challenges to effective management. Traditional Chinese medicine (TCM) offers a holistic approach, emphasizing syndrome differentiation, individualized care, and natural treatment strategies.Qin‐Wei Fu, Peng Liu, Yan Ruan, Xin‐Rong Li, Lan‐Zhi Zhang, Sha‐Sha Yang, Feng Chai, Ji Chen, Qiao‐Yan Chen, Shu‐Cheng Chen, Wen‐Yong Chen, Yong‐Na Chen, Hong‐Bin Cheng, Lei Cheng, Lu‐Jia Cui, Ke‐Bin Deng, Cai‐Shan Fang, Rong‐Chang Feng, Li Fu, Wen‐Yang Fu, Jian‐Ying Gao, Hong Guo, Miao He, Ko‐Hsin Hu, Chun‐Jiang Huang, He‐Yin Huang, Lu‐Yun Jiang, Feng‐Ying Qiao, Hui Leng, Yun‐Ying Li, Chun‐Song Liu, Da‐Xin Liu, Jian‐Hua Liu, Jin‐Hui Liu, Jing Liu, Min Liu, Wei‐Ting Liu, Yuan‐Xian Liu, Yang Liu, Ying Liu, Zhi‐Qing Liu, Qiu‐Lan Luo, Yu Ma, De‐Hong Mao, Juan Meng, Kai‐Yun Pang, Shun‐Lin Peng, Xuan‐Fu Tong, Ji Wang, Jia‐Xi Wang, Jun‐Ge Wang, Ren‐Zhong Wang, Shi‐Zhen Wang, Ji‐Yan Xia, Hui Xie, Qiang Xie, Yan Xie, Da‐Jing Xiong, Zhan‐Feng Yan, Hui Yang, Da‐Zheng Zhang, Fu‐Bing Zhang, Shi‐Peng Zhang, Zhi‐Cheng Zhang, Ji‐Ping Zhao, Yu Zhao, Yun Zheng, Dan‐Zhu Zhong, Li Zhou, Valentin Mikhailovich Knyazev, Irina Viktorovna Kostrova, Wing‐Fai Yeung, Qi Wang, De‐Yun Wang, Qin‐Xiu Zhang +74 morewiley +1 more sourceProtective Role for Itaconate During Inhaled Allergen Challenge
Allergy, EarlyView.Itaconate levels decrease in sputum following allergen inhalation in mild asthmatics, suggesting a dynamic metabolic response to airway challenge. Genetic deletion of Acod1 in mice did not alter airway inflammation or remodelling in response to chronic HDM exposure.Gesa J. Albers, Patricia P. Ogger, Christina Michalaki, Helen Stölting, Simone A. Walker, Anna Caldwell, John M. Halket, Kathryn Duvall, Atia Batool, Lisha Joshi, Helen O'Brien, Cormac McCarthy, Timothy Hinks, Gail M. Gauvreau, Paul M. O'Byrne, Clare M. Lloyd, Adam J. Byrne +16 morewiley +1 more sourcePeanut Component‐Specific IgE and IgG4 Are Modulated by Sublingual Immunotherapy and Are Associated With Remission in 1–4‐Year‐Old Children
Allergy, EarlyView.This study presents a post hoc analysis of longitudinal changes in peanut component‐specific IgE and IgG4 in children aged 1–4 years undergoing peanut SLIT, aiming to uncover immune mechanisms and potential biomarkers of remission. Peanut SLIT reduced IgE and increased IgG4 responses to Ara h 1, Ara h 2, Ara h 3, and Ara h 6.Neel Singh, Janelle Kesselring, Jess Humphrey, Lauren Herlihy, A. Wesley Burks, Johanna Smeekens, Corinne Keet, J. Andrew Bird, Edwin H. Kim, Michael Kulis +9 morewiley +1 more sourceThaumatin‐Like Proteins in Molecular Allergy Diagnostics: Uncommon, Co‐Sensitized, and Clinically Inconspicuous? Insights From an Italian Cohort
Allergy, EarlyView.This study assessed the prevalence, quantitative IgE levels, co‐sensitization patterns, and clinical significance of IgE reactivity to two TLPs—Act d 2 (kiwi) and Mal d 2 (apple)—in a large Italian allergic cohort. Thaumatin‐like protein (TLP) sensitization was uncommon (1.9%) and usually clinically silent when isolated.Enrico Scala, Damiano Abeni, Mauro Giani, Valeria Villella, Elisabetta Caprini, Ignazio Brusca, Lorenzo Cecchi, Danilo Villalta, Riccardo Asero +8 morewiley +1 more source
