Results 11 to 20 of about 2,071,364 (242)

A novel detection method for cross-linking of IgE-receptors by autoantibodies in chronic spontaneous urticaria

Allergology International, 2022
Background: Autoantibodies (AAbs) against immunoglobulin E (IgE) antibodies (Abs) and their high-affinity receptor alpha subunits (FcεRIα) are key factors in the elicitation of type IIb autoimmune chronic spontaneous urticaria (type IIb aiCSU).
Yuki Koga, Tomoharu Yokooji, Ryohei Ogino, Takanori Taogoshi, Shunsuke Takahagi, Kaori Ishii, Yuko Chinuki, Eishin Morita, Michihiro Hide, Hiroaki Matsuo   +9 more
doaj   +1 more source

Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus [PDF]

, 2008
High levels of serum IgE are considered markers of parasite and helminth exposure. In addition, they are associated with allergic disorders, play a key role in anti-tumoral defence, and are crucial mediators of autoimmune diseases.
Wichmann, H. -Erich, Ursula Krämer, Liang Liming, Markus Ollert, Stephan Weidinger, Mempel, Martin, Bauer, Carl Peter, Baurecht Hansjörg, Prokisch Holger, Mehta Divya, von Berg, A., von Mutius, Erika, Bauer Carl Peter, Gohlke, H., Cookson, W., Depner, Martin, Wagenpfeil, S., Wichmann, H.-E., Illig, T., Michael Kabesch, Mempel, M., Novak, N., Mehta, D., Illig Thomas, Liang, L., Kabesch, Michael, von Berg Andrea, Moffatt Miriam, Prokisch, H., Heinrich Joachim, Herbarth, Olf, Gohlke Henning, Bieber, Thomas, Olf Herbarth, Martin Depner, Stefan Wagenpfeil, Heinrich, Joachim, H-Erich Wichmann, Erika von Mutius, Heinrich, J., Gieger, Christian, Heidrun Behrendt, Ollert Markus, Thomas Bieber, Meitinger, T., Divya Mehta, Ring, Johannes, Rodriguez Elke, Herbarth Olf, Miriam Moffatt, Natalija Novak, von Mutius Erika, Cookson William, Mehta, Divya, Behrendt Heidrun, Klopp, Norman, Ring Johannes, Bieber Thomas, Cookson, William, Sibylle Koletzko, Meitinger Thomas, Wichmann, Heinz-Erich, Mempel Martin, Hansjörg Baurecht, William Cookson, Kraemer, Ursula, Gieger, C., Gohlke, Henning, Christian Gieger, Baurecht, H., Depner Martin, Kabesch Michael, Weidinger, S., Bieber, T., Herbarth, O., Novak, Natalija, Berdel Dietrich, Moffatt, M., Berdel, D., von Mutius, E., Koletzko, Sibylle, Klopp, N., Krämer Ursula, Gieger Christian, Liang, Liming, Bauer, C.P., Johannes Ring, Berdel, Dietrich, Wagenpfeil, Stefan, Mutius, Erika von, Koletzko Sibylle, Koletzko, S., Rodriguez, E., Krämer, U., Ollert, Markus, Ollert, M., Rodriguez, Elke, Wichmann H.-Erich, Kabesch, M., Behrendt, H., Prokisch, Holger, Moffatt, Miriam, Henning Gohlke, Carl Peter Bauer, Illig, Thomas, Meitinger, Thomas, Liming Liang, Joachim Heinrich, Andrea von Berg, Thomas Illig, Novak Natalija, von Berg, Andrea, Weidinger, Stephan, Weidinger Stephan, Klopp Norman, Baurecht, Hansjoerg, Behrendt, Heidrun, Thomas Meitinger, Depner, M., Berg, Andrea von, Dietrich Berdel, Ring, J., Wagenpfeil Stefan, Elke Rodriguez, Norman Klopp, Martin Mempel, Holger Prokisch, Weidinger, S;Gieger, C;Rodriguez, E;Baurecht, H;Mempel, M;Klopp, N;Gohlke, H;Wagenpfeil, S;Ollert, M;Ring, J;Behrendt, H;Heinrich, J;Novak, N;Bieber, T;Kramer, U;Berdel, D;von Berg, A;Bauer, CP;Herbarth, O;Koletzko, S;Prokisch, H;Mehta, D;Meitinger, T;Depner, M;von Mutius, E;Liang, L;Moffatt, M;Cookson, W;Kabesch, M;Wichmann, HE;Illig, T   +127 more
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Genetic variation among lambs in peripheral IgE activity against the larval stages of Teladorsagia circumcincta [PDF]

, 2010
IgA and IgE activity against Teladorsagia circumcincta was investigated in a flock of Texel lambs following natural, mixed nematode infection among lambs.
Bishop, S. C., Eckersall, P.D., Bishop, S.C., Burchmore, R., Pettit, J.J., Stear, M.J., Eckersall, P. D., Pettit, J. J., Huntley, J. F., Huntley, J.F., Burchmore, R.J.S., Stear, M. J., Murphy, L.   +12 more
core   +1 more source

The structure of human CD23 and its interactions with IgE and CD21 [PDF]

, 2005
The low-affinity immunoglobulin E ( IgE) receptor, CD23 ( Fc epsilon RII), binds both IgE and CD21 and, through these interactions, regulates the synthesis of IgE, the antibody isotype that mediates the allergic response.
Grundy, GJ, Hibbert, R G, Peter Teriete, Jonathan P. Hannan, Brian J. Sutton, Rajko Reljić, Gould, H J, Rebecca L. Beavil, Holers, V M, Hannah J. Gould, Holers, VM, Richard G. Hibbert, McDonnell, JM, Gabrielle J. Grundy, Hibbert, RG, Sutton, BJ, James M. McDonnell, Reljic, R, V. Michael Holers, Grundy, G J, Gould, HJ, Hannan, JP, Beavil, R L, Sutton, B J, Teriete, P, Beavil, RL, McDonnell, J M; id_orcid, Hannan, J P   +27 more
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Eosinophilic granulomatosis with polyangiitis: overcoming diagnostic obstacles and exploring pharmacotherapeutic approaches [PDF]

Exploration of Immunology
Eosinophilic granulomatosis with polyangiitis (EGPA) is an uncommon form of necrotizing vasculitis that affects the respiratory system and other organs, characterized by asthma, eosinophilia, and multiple organ involvement that complicates the diagnosis ...
Priya Komre, Akash Gupta, Sanjay Kumar Gupta, Tomy Muringayil Joseph, Debarshi Kar Mahapatra   +4 more
doaj   +1 more source

Environmental determinants of total IgE among school children living in the rural Tropics: importance of geohelminth infections and effect of anthelmintic treatment. [PDF]

, 2008
BACKGROUND: The environmental factors that determine the elevated levels of polyclonal IgE observed in populations living in the Tropics are poorly understood but may include geohelminth infections.
Cooper Philip J, Griffin, GE, Cooper, Philip J, Chico Martha E, Vaca, MG, Alexander Neal, Chico, ME, Benitez, Susana M, Ana-Lucia Moncayo, Vaca, Maritza G, Chico, Martha E, Benitez Susana M, Moncayo, Ana-Lucia, Alexander, N, Griffin, George E, Vaca Maritza G, Maritza G Vaca, Susana M Benitez, Neal Alexander, Martha E Chico, Griffin George E, Benitez, SM, Philip J Cooper, Alexander, Neal, Moncayo, AL, George E Griffin, Moncayo Ana-Lucia, Cooper, PJ   +27 more
core   +1 more source

Nível sérico de IgE total em alergia respiratória: estudo em pacientes com alto risco de infecção por helmintos Total IgE level in respiratory allergy: study of patients at high risk for helminthic infection

Jornal de Pediatria, 2006
OBJETIVO: Eosinofilia e elevação de IgE sérica são expressões de atopia, contudo há fatores intervenientes como, por exemplo, as parasitoses intestinais.
Décio Medeiros, Almerinda Rego Silva, José Angelo Rizzo, Maria Eugênia Motta, Francisca Hosana Bezerra de Oliveira, Emanuel Sávio Cavalcanti Sarinho   +5 more
doaj   +1 more source

Effects of geohelminth infection and age on the associations between allergen-specific IgE, skin test reactivity and wheeze: a case-control study. [PDF]

, 2013
BACKGROUND: Most childhood asthma in poor populations in Latin America is not associated with aeroallergen sensitization, an observation that could be explained by the attenuation of atopy by chronic helminth infections or effects of age.
Oviedo, G, Platts-Mills, TA, Vaca, M., Workman, L. J., Platts-Mills, T. A. E., Barreto, M. L., Rodrigues, LC, Moncayo, A-L, Workman, LJ, Vaca, M, Chico, ME, Platts-Mills, TAE, Oviedo, G., Barreto, ML, Moncayo, AL, Rodrigues, L. C., Chico, M. E., Cooper, PJ, Cooper, Philip, Moncayo, A.-L.   +19 more
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Differential effects of the Toll-like receptor 2 agonists, PGN and Pam3CSK4 on anti-IgE induced human mast cell activation. [PDF]

PLoS ONE, 2014
Mast cells are pivotal in the pathogenesis of allergy and inflammation. In addition to the classical IgE-dependent mechanism involving crosslinking of the high-affinity receptor for IgE (FcεRI), mast cells are also activated by Toll-like receptors (TLRs)
Yangyang Yu, Kwok Ho Yip, Issan Yee San Tam, Sze Wing Sam, Chun Wai Ng, Wei Zhang, Hang Yung Alaster Lau   +6 more
doaj   +1 more source

Glycan-specific IgG anti-IgE autoantibodies are protective against allergic anaphylaxis in a murine model. [PDF]

, 2021
BACKGROUND IgE causes anaphylaxis in type-1 hypersensitivity diseases by activating degranulation of effector cells such as mast cells and basophils.
Bachmann, Martin F., Frias Boligan, Kayluz, Thoms, Franziska, Vogel, Monique, Engeroff, Paul, Storni, Federico, Plattner, Kevin, Mürner, Lukas, von Gunten, Stephan, Eggel, Alexander   +9 more
core   +3 more sources