Results 21 to 30 of about 2,071,364 (242)

Recombinant soluble form of the high-affinity IgE receptor α subunit and anti-IgE antibody inhibit IgE synthesis by IgE-expressing B cells through distinct pathways

Allergology International, 2002
Background: Both a recombinant soluble form of the high-affinity IgE receptor α subunit (rsFcεRIα) and anti-IgE antibody have been shown to be involved in the regulation of IgE synthesis.
Keiichi Kajiwara, Chisei Ra, Yukiyoshi Yanagihara   +2 more
doaj   +1 more source

Real-life biomarker response to anti-IL5 and anti-IgE therapies in severe asthma patients

, 2022
Introduction/Background: Biologics (Bx) are known to decrease specific biomarker levels: anti-IL5 reduces blood eosinophils (BEC) and anti-IgE slightly reduces FeNO. Anti-IL5 and anti-IgE are thought to have limited effect on total IgE (IgE).
Barker, P, Lyu, J, Bourdin, A, Christoff, GC, Burkill, S, Martin, N, Popov, TA, Tran, TN, Porsbjerg, CM, Katial, R, Wechsler, ME, Chung, LP, Katsoulotos, G, Bosnic-Anticevich, S, Maspero, J, et al.   +15 more
core   +1 more source

Ascaris lumbricoids Infection as a Risk Factor for Asthma and Atopy in Rural Bangladeshi Children. [PDF]

, 2014
Controversy persists as to whether helminth infections cause or protect against asthma and atopy. The aim of this study was to investigate the effects of helminth infection on asthma and atopy among Bangladeshi children.
Persson, Lars Å, Noguchi, Emiko,, Itoh, Makoto,, Noguchi, Emiko, Wagatsuma, Yukiko,, Raqib, Rubhana,, Wagatsuma, Yukiko, Ma, Enbo, Moore, Sophie E; id_orcid, Moore, Sophie E,, Moore, Sophie E, Persson, Lars-Åke,, Raqib, Rubhana, Hawlader, Mohammad D H, Hawlader, Mohammad D H,, Arifeen, Shams E,, Arifeen, Shams E, Ma, Enbo,, Itoh, Makoto, Hawlader, Mohammad DH   +19 more
core   +1 more source

Futtermittel-spezifisches IgG und IgE vor und nach Eliminationsdiäten bei allergischen Hunden [PDF]

, 2012
Serum food allergen-specific antibody testing is widely offered to identify suitable ingredients for diets to diagnose adverse food reaction (AFR) in dogs with allergic skin disease.
Zimmer, Anja
core   +1 more source

Detection of anti-IgE anti-FcεRI α chain auto-antibodies in patients with atopic dermatitis

Allergology International, 2000
Anti-IgE and anti-FcεRI α chain auto-antibodies have been detected in the sera of atopic and non-atopic subjects; however, the biological activity of these auto-antibodies is still unclear.
Satoru Hayashi, Hajime Suto, Naruhito Wada, Hideoki Ogawa, Ko Okumura, Chisei Ra   +5 more
doaj   +1 more source

Clinical Characterization of Patients with Chronic Spontaneous Urticaria according to Anti-TPO IgE Levels

Journal of Immunology Research, 2019
Background. Chronic spontaneous urticaria (CSU) is a heterogeneous disease with some frequent comorbidities like autoimmune diseases, drug reactions, and inducible urticaria.
Jorge Sánchez, Andres Sánchez, Ricardo Cardona   +2 more
doaj   +1 more source

Real‐life effectiveness of biological therapies on symptoms in severe asthma with comorbid CRSwNP

Clinical and Translational Allergy, 2021
Background We aimed to evaluate the effectiveness of different antibody therapies on nasal polyp symptoms in patients treated for severe asthma. Methods We performed a retrospective analysis of patients with severe asthma and comorbid CRSwNP who were ...
Carlo Mümmler, Kristin Dünzelmann, Nikolaus Kneidinger, Michaela Barnikel, Dieter Munker, Moritz Gröger, Martin Canis, Jürgen Behr, Andrea Koch, Frank Haubner, Katrin Milger   +10 more
doaj   +1 more source

Bispecific T-Cell Engagers Targeting Membrane-Bound IgE

Biomedicines, 2021
The increased incidence of allergies and asthma has sparked interest in IgE, the central player in the allergic response. Interaction with its high-affinity receptor FcεRI leads to sensitization and allergen presentation, extracellular membrane-proximal ...
Aleksandra Rodak, Gerhard Stadlmayr, Katharina Stadlbauer, Dominic Lichtscheidl, Madhusudhan Reddy Bobbili, Florian Rüker, Gordana Wozniak-Knopp   +6 more
doaj   +1 more source

好塩基球からのヒスタミン遊離に関する研究. 1 自動分析装置による全血からのヒスタミン遊離の測定 [PDF]

, 1983
Histamine released from whole blood was determined by an automated fiuorometric histamine analysis system. The increased release of histamine from basophils by anti-IgE was observed in ten healthy subjects and 12 extrinsic asthma patients, while the ...
Tanizaki, Yoshiro, Goda, Yoshinori, Kitani, Hikaru, Sudo, Michiyasu, Morinaga, Hiroshi, Kimura, Ikuro, Tada, Shinya, Mifune, Masaaki, Ohtani, Jun, Komagoe, Haruki   +9 more
core   +1 more source

NOSOTROPIC SUBSTANTIATION OF ANTI IgE ANIBODY THERAPY

Педиатрическая фармакология, 2008
This article studies the specifics of allergic diseases pathogenesis. Such common allergic diseases as bronchial asthma, allergic rhinitis and atopic dermatitis are conditioned by processes based on increase of immunoglobulin e synthesis.
Yu.G. Levina
doaj   +2 more sources