Results 161 to 170 of about 9,467,496 (262)

Case Report: Interim success in treating pyogenic spondylitis caused by Staphylococcus epidermidis using UBE technology: a rare case. [PDF]

Front Surg
Chen X, Rao J.
europepmc   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

Application of metagenomic next-generation sequencing in children with pneumonia of unknown etiology. [PDF]

Front Cell Infect Microbiol
Huang H, Fu Y, Liu E, Bai K, Li J, Liu C, Deng Y, Xu F.   +7 more
europepmc   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

Exploring the Bioactive Properties of <i>Thymus kotschyanus</i> var. <i>kotschyanus</i> and Endemic <i>Thymus brachychilus</i>: From Plant Extracts to Alginate Film Formulations for Wound Infection Management. [PDF]

Pharmaceutics
Rayaman E, Zengin FB, Taşkın D, Atıcı CE, Kılıç Ö, Salihi EÇ, Taşkın T, Şahan Z, Elçioğlu HK.   +8 more
europepmc   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Generalized Hailey&ndash;Hailey Disease Complicated by MRSA Infection: A Case Report of Management with Systemic Corticosteroids and Targeted Anti-Infective Therapy

Clinical, Cosmetic and Investigational Dermatology
Changlin Sui,1,&ast; Jintao Chuan,2,&ast; Yanjie Wei,2 Xue Li,1 Lu Zhang1,31Department of Dermatology, Qingdao University Medical College Affiliated Yantai Yuhuangding Hospital, Yantai, Shandong, People’s Republic of China; 2Department of ...
Sui C, Chuan J, Wei Y, Li X, Zhang L
doaj  

Nanorobots Are Using Light and Clever Engineering to Beat Biofilms and Tackle Antimicrobial-Resistant Infections. [PDF]

J Med Internet Res
Critchley L.
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Campylobacter jejuni as a Rare Pathogen in CIED Pocket Infections: A Case Report and Literature Review. [PDF]

Am J Case Rep
Barańska-Pawełczak K, Ziaja B, Opara M, Jacheć W.   +3 more
europepmc   +1 more source