Results 191 to 200 of about 29,477 (217)

Public contributions to the development of antibiotics: two successful and two failed investments. [PDF]

J Pharm Policy Pract
Schmidt L, Sehic O, Theuretzbacher U, Wild C.   +3 more
europepmc   +1 more source

Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

Advanced Science, EarlyView.
Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang, Qin Wang, Zhuo Yao, Qing Wang, Yongtao Ji, Minqi Yang, Meng Wang, Shiyi Shao, Xinyu Zhao, Fu Zhang, Tingbo Liang, Qida Hu   +11 more
wiley   +1 more source

Microneedle-guided monitoring and therapy in chronic limb-threatening ischemia. [PDF]

Front Cell Dev Biol
Zhang Z, Zhao XD, Ahamujiang A, Wang YH, Long C, Wang G.   +5 more
europepmc   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Advances in diagnosis and treatment of lung cancer-associated obstructive pneumonia and lung abscess: synergistic strategies for infection control and antitumor therapy. [PDF]

Front Cell Infect Microbiol
Cao P, Chen L, Xie S, Hu B.
europepmc   +1 more source

Two-stage revision combined with anti-infective therapy for mixed fungal and bacterial knee periprosthetic joint infection: a case report and literature review. [PDF]

BMC Musculoskelet Disord
Zhang L, Yang X, Huang X, Yang L.
europepmc   +1 more source

Case Report: Contrast-enhanced ultrasonography for evaluating a newly detected contralateral pulmonary lesion during non-small cell lung cancer chemoimmunotherapy. [PDF]

Front Immunol
Liu Y, Feng L, Yang X, Wen S, Xiang Y, Ma X, Zhou R, Du W.   +7 more
europepmc   +1 more source

Natural and Synthetic Peptides as Alternatives to Antibiotics in Intestinal Infections-A Review. [PDF]

Antibiotics (Basel)
Stepanyan L, Israyelyan M, Gori A, Tsaturyan A, Saribekyan Z, Hovsepyan K, Sargsyan T, Pastore R, De Luca A, Roviello GN.   +9 more
europepmc   +1 more source

Eosinophilic Myocarditis and Nonbacterial Thrombotic Endocarditis in a Patient With Immunoglobulin G4-Related Disease: A Case Report and Review. [PDF]

Int J Heart Fail
Sun J, Yang J, Lee J, Yoon WS, Kim SM, Kwon J, Kang MG, Lee OJ, Bae DH.   +8 more
europepmc   +1 more source