Results 141 to 150 of about 13,174 (165)

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

Pediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang, Fuping Yang, Chunyu Yan, Yu Deng, Enmei Liu   +4 more
wiley   +1 more source

Antimicrobial Resistance: The Answers. [PDF]

Br J Biomed Sci
Millar BC, Cates MJ, Torrisi MS, Round AJ, Warde A, Lowery CJ, Moore JE.   +6 more
europepmc   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Mycoplasma hominis infections in deep sternal wound infections post-cardiac surgery: insights from three case reports. [PDF]

BMC Infect Dis
Wei Q, Cong R, Liu T, Liu K, Zhao G, Dong S.   +5 more
europepmc   +1 more source

Conservation status of species used in the UK herbal medicine industry

PLANTS, PEOPLE, PLANET, EarlyView.
Given the ongoing biodiversity crisis, sustainable use and management of medicinal plants is critical. We assessed the conservation status, threats and conservation actions of 298 species sold by UK suppliers to medical herbalists. We found that most species used are unevaluated, representing a gap in conservation knowledge, and of those with ...
Isabella Flowers, Jon C. Lovett, Christopher Hassall   +2 more
wiley   +1 more source

The UK Antimicrobial Registry (UKAR): an overview of the first 20 months of recruitment. [PDF]

JAC Antimicrob Resist
Sneddon J, Parr R, Woods J, MacDonald RIR, Sandoe JAT, Baltas I, Seaton RA, El Sakka N, Kaye C, Macfarlane GJ, Jones GT, UKAR Study Principal Investigators .   +11 more
europepmc   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source

Point-prevalence of healthcare-associated infections and antimicrobial use in a tertiary hospital in Shanghai, China: 2012-2023. [PDF]

Antimicrob Resist Infect Control
Yang Y, Shen R, Lu F, Cai B, Huang M, Ding J, Yuan Y, Gui X, Yan S, Li L, Huang S, Fu X, Ban H, Gong X, Wang Z.   +14 more
europepmc   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Impact of Pharmacist-Led Anti-Infective Consultations on Therapeutic Outcomes: A Retrospective Cohort Study in a Tertiary Hospital. [PDF]

Infect Drug Resist
Xin C, Zheng B, Zhao Q, Yang W, Feng P, Tu Y.   +5 more
europepmc   +1 more source