Results 131 to 140 of about 3,594,283 (182)
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Therapeutic drug monitoring of anti-infective agents in critically ill patients
Expert Review of Clinical Pharmacology, 2016 Initial adequate anti-infective therapy is associated with significantly improved clinical outcomes for patients with severe infections. However, in critically ill patients, several pathophysiological and/or iatrogenic factors may affect the ...
Jason Roberts, Nynke G L Jager
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Infections, Anti-infective Agents, and Risk of Deliberate Self-harm and Suicide in a Young Cohort: A Nationwide Study [PDF]
Biological Psychiatry, 2019 BACKGROUND: Evidence links infections to mental disorders and suicidal behavior. However, knowledge is sparse regarding less severe infections, anti-infective treatment, and deliberate self-harm.
Ole Köhler +2 more
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Benzothiazole Derivatives as Potential Anti-Infective Agents
Current Topics in Medicinal Chemistry, 2016Severity of microbial infections and escalating resistance towards antibiotics has created a deep necessity for discovery of novel anti-infective agents. Heterocyclic chemistry of benzothiazole has become one of the most prolific areas in the field of drug discovery and development that has attracted great attention in recent time due to its increasing
Meenakshi pathak +2 more
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Cheminformatics in Anti-Infective Agents Discovery
Mini-Reviews in Medicinal Chemistry, 2007The existing chemical data such as those created by high throughput screening (HTS), structure-activity relationship (SAR) studies are converted into information as a result of storage and registration. Accessibility, manipulation, and data mining of such information make up the knowledge for drug development.
S, Sardari, M, Dezfulian
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Anti-infective agents and hepatic disease
Medical Clinics of North America, 1995Numerous factors such as changes in plasma protein binding, tissue binding, hepatic blood flow, hepatic metabolism, and distribution may occur in hepatic disease. The impact of these physiologic changes on pharmacokinetic and pharmacodynamic parameters of anti-infective agents is likely to be clinically significant. Unfortunately, these issues have not
S J, Tschida, K, Vance-Bryan, D E, Zaske
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1995
Chemotherapeutic agents are intended to eliminate foreign organisms or abnormal cells from healthy tissues of the patient. An essential property of all chemotherapeutic drugs is selective toxicity; deleterious actions directed against the target cells without comparable effects on the tissue of the host.
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Chemotherapeutic agents are intended to eliminate foreign organisms or abnormal cells from healthy tissues of the patient. An essential property of all chemotherapeutic drugs is selective toxicity; deleterious actions directed against the target cells without comparable effects on the tissue of the host.
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1984
In the 50-year period since Fleming made his monumental discovery of penicillin, a vast array of anti-infective agents have been developed to combat the plethora of infectious microorganisms plaguing mankind. While once the ophthalmologist had only penicillin to resort to when faced with ocular infection, his choice now includes myriads of antibiotics.
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In the 50-year period since Fleming made his monumental discovery of penicillin, a vast array of anti-infective agents have been developed to combat the plethora of infectious microorganisms plaguing mankind. While once the ophthalmologist had only penicillin to resort to when faced with ocular infection, his choice now includes myriads of antibiotics.
openaire +1 more source