Synthesis and Structure-Activity Relationships of Imidazopyridine/Pyrimidine- and Furopyridine-Based Anti-infective Agents against Trypanosomiases. [PDF]
Silva DG +10 more
europepmc +1 more source
From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss +9 more
wiley +1 more source
Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram +25 more
wiley +1 more source
Isolation And Characterization Of Marine Actinomycetes For Anti-Infective Activity Towards Pseudomonas aeruginosa PA14 [PDF]
Marine environment serve as reservoir of vast useful secondary metabolites and at the same time, new anti-infective agents are required to combat antibiotic resistant pathogenic bacteria.Therefore, this research was carried out to screen for anti ...
Kamal, Siti Nur Fatin Ahmad
core +1 more source
Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study
Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali +11 more
wiley +1 more source
Inflammatory response to sars-cov 2 and other respiratory viruses
Introduction: Lower respiratory tract infections (LRTI) remain a significant global cause of mortality and disability. Viruses constitute a substantial proportion of LRTI cases, with their pandemic potential posing a latent threat.
Martín-Loeches I +4 more
core +1 more source
Avaliação da atividade anti-herpética de cardenolídeos e derivados [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina. Programa de Pós-Graduação em Biotecnologia, Florianópolis, 2011Os cardenolídeos pertencem a um grupo de compostos naturais, que inibem a bomba de Na+/K+ (NKATPase).
Bertol, Jéssica Wildgrube
core
Introduction & Objective: During the most dental procedures, contamination of devices with blood, saliva and other body fluids, which is the most important factor for transmission of infectious diseases, is inevitable.
Amir Eskandarloo, Rasool Yousefi Mashouf
doaj
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler +20 more
wiley +1 more source
Septic emboli secondary to Infective Endocarditis [PDF]
A 31 year old lady was brought to casualty by a friend, unconscious and incontinent of urine and faeces. She was responsive to verbal stimuli with a Glasgow Come Scale (GCS) of 10 and noted to have a fever of 39.6oC.
Pavia, Jessica +2 more
core

