Results 101 to 110 of about 162,736 (290)
, 2019 Annona species have been a valuable source of anti-infective and anticancer agents. However, only limited evaluations of their alkaloids have been carried out. This review collates and evaluates the biological data from extracts and purified isolates for
Paul Keller (19587565) +3 more
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FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Isolation And Characterization Of Marine Actinomycetes For Anti-Infective Activity Towards Pseudomonas aeruginosa PA14 [PDF]
, 2018 Marine environment serve as reservoir of vast useful secondary metabolites and at the same time, new anti-infective agents are required to combat antibiotic resistant pathogenic bacteria.Therefore, this research was carried out to screen for anti ...
Kamal, Siti Nur Fatin Ahmad
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Marine Peptides and Their Anti-Infective Activities
, 2015 Marine bioresources are a valuable source of bioactive compounds with industrial and nutraceutical potential. Numerous clinical trials evaluating novel chemotherapeutic agents derived from marine sources have revealed novel mechanisms of action. Recently,
Chang Seo +4 more
core +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Avaliação da atividade anti-herpética de cardenolídeos e derivados [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina. Programa de Pós-Graduação em Biotecnologia, Florianópolis, 2011Os cardenolídeos pertencem a um grupo de compostos naturais, que inibem a bomba de Na+/K+ (NKATPase).
Bertol, Jéssica Wildgrube
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FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Current status of imaging infections with radiolabeled anti-infective agents
, 2009 Infection specific radiopharmaceuticals can be used for diagnosis, decision-making in therapy and treatment follow-up. Research has been ongoing to develop infection specific markers since clinically used tracers cannot discriminate between infection and
Ferro-Flores, G. +3 more
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Design, synthesis, and structure-activity relationships of GPR35 agonists and antagonists and design, synthesis, and anti-microbial evaluation of pyrazole derivatives [PDF]
, 2015 GPR35, a G protein-coupled receptor (GPCR), was discovered and specified as an orphan receptor in 1998. GPR35 has been described as a prospective therapeutic target as a result of its association with many diseases including type-2 diabetes, nociceptive ...
Abdalhameed, Manahil Mirghani Ali +1 more
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