Results 281 to 290 of about 122,751 (340)
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Cheminformatics in Anti-Infective Agents Discovery
Mini-Reviews in Medicinal Chemistry, 2007The existing chemical data such as those created by high throughput screening (HTS), structure-activity relationship (SAR) studies are converted into information as a result of storage and registration. Accessibility, manipulation, and data mining of such information make up the knowledge for drug development.
S, Sardari, M, Dezfulian
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Antimicrobial peptides: Possible anti-infective agents
Peptides, 2015Multidrug-resistant bacterial, fungal, viral, and parasitic infections are major health threats. The Infectious Diseases Society of America has expressed concern on the decrease of pharmaceutical companies working on antibiotic research and development.
Jayaram, Lakshmaiah Narayana +1 more
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Anti-infective agents and hepatic disease
Medical Clinics of North America, 1995Numerous factors such as changes in plasma protein binding, tissue binding, hepatic blood flow, hepatic metabolism, and distribution may occur in hepatic disease. The impact of these physiologic changes on pharmacokinetic and pharmacodynamic parameters of anti-infective agents is likely to be clinically significant. Unfortunately, these issues have not
S J, Tschida, K, Vance-Bryan, D E, Zaske
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1984
In the 50-year period since Fleming made his monumental discovery of penicillin, a vast array of anti-infective agents have been developed to combat the plethora of infectious microorganisms plaguing mankind. While once the ophthalmologist had only penicillin to resort to when faced with ocular infection, his choice now includes myriads of antibiotics.
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In the 50-year period since Fleming made his monumental discovery of penicillin, a vast array of anti-infective agents have been developed to combat the plethora of infectious microorganisms plaguing mankind. While once the ophthalmologist had only penicillin to resort to when faced with ocular infection, his choice now includes myriads of antibiotics.
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1995
Chemotherapeutic agents are intended to eliminate foreign organisms or abnormal cells from healthy tissues of the patient. An essential property of all chemotherapeutic drugs is selective toxicity; deleterious actions directed against the target cells without comparable effects on the tissue of the host.
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Chemotherapeutic agents are intended to eliminate foreign organisms or abnormal cells from healthy tissues of the patient. An essential property of all chemotherapeutic drugs is selective toxicity; deleterious actions directed against the target cells without comparable effects on the tissue of the host.
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Pharmacogenomics of Anti-Infective Agents
2020Ever since we know that the dissimilarities of medications are influenced by the in vivo process of the body, including absorption, distribution, metabolization, and excretion, great attentions have been paid on pharmacogenomic issues, trying to figure out the underlying mechanisms of drug response deviations.
Xianmin Meng, Qian Zhang, Ping Dong
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Benzothiazole Derivatives as Potential Anti-Infective Agents
Current Topics in Medicinal Chemistry, 2016Severity of microbial infections and escalating resistance towards antibiotics has created a deep necessity for discovery of novel anti-infective agents. Heterocyclic chemistry of benzothiazole has become one of the most prolific areas in the field of drug discovery and development that has attracted great attention in recent time due to its increasing
Sharma, Prabodh Chander +3 more
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