Results 291 to 300 of about 112,322 (317)
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Pharmacokinetics of Anti-Infective Agents in Paediatric Patients
Clinical Pharmacokinetics, 1994Various differences in drug disposition exist between children and adults. For example, the volume of distribution (Vd) for many drugs is larger in children than in adults. Other parameters, including excretion and elimination may be altered in children compared with adults.
Mary H. H. Chandler +2 more
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Hyperbaric oxygen therapy as an anti-infective agent
Expert Review of Anti-infective Therapy, 2009Hyperbaric oxygen therapy (HBOT) involves inhalation of 100% oxygen at supra-atmospheric ambient pressure. HBOT is used as either a primary or adjunctive treatment in the management of infections such as gas gangrene, necrotizing fasciitis, diabetic foot infections, refractory osteomyelitis, neurosurgical infections and fungal infections.
Guenalp Uzun, Senol Yildiz, Maide Cimsit
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Clinical Use of Anti-infective Agents
2012clinical use of anti-infective agents , clinical use of anti-infective agents , کتابخانه دیجیتالی دانشگاه علوم پزشکی و خدمات درمانی شهید ...
Roy Guharoy, Robert W. Finberg
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Antimicrobial peptides: Possible anti-infective agents
Peptides, 2015Multidrug-resistant bacterial, fungal, viral, and parasitic infections are major health threats. The Infectious Diseases Society of America has expressed concern on the decrease of pharmaceutical companies working on antibiotic research and development.
Jayaram Lakshmaiah Narayana +2 more
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Defensins as anti-infective and immunomodulatory agents
Expert Opinion on Therapeutic Patents, 2006Defensins are a large family of polypeptides occuring in most animals and plants. Since the first description of a defensin in 1985, the members of this peptide class are considered to play an important role in the innate immune defence of organisms, protecting against invading pathogens by killing bacteria and other microbes.
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Antibody-based therapies as anti-infective agents
Expert Opinion on Investigational Drugs, 1998Antibody-based therapies are effective against a wide variety of pathogens. Historically, antibody-based therapies were largely abandoned with the advent of antimicrobial chemotherapy, due to the toxicity associated with the administration of heterologous immune sera.
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Therapeutic drug monitoring of intracellular anti-infective agents
Journal of Pharmaceutical and Biomedical Analysis, 2014Many microorganisms, including viruses, some bacteria and fungi, replicate within the cells. Therefore, the efficacy of therapy and the selection of resistances could be related to intracellular concentration of the drugs and to their ability to cross biological membranes and penetrate into various tissue compartments.
D'AVOLIO, ANTONIO +3 more
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Discovery of novel anti-infective agents
Academic and other non-profit institutions have a long-term vision to improve human health where commercial interests can be limited for profit organizations. Medicinal chemistry to these diseases with no commercial benefit needs is well suited in the academic environment and this chapter outlines some work conducted at Calibr-Skaggs around antibiotic ...openaire +2 more sources