Cytokine, Chemokine, and Neurofilament Light Chain Signatures in LGI1 Autoimmune Encephalitis
ABSTRACT Objectives To investigate the value of cytokine, chemokine, and neurofilament light chain (NfL) concentrations in predicting relapse risk, chronic epilepsy, and functional impairment in LGI1 autoimmune encephalitis (AE). Methods Cytokines/chemokines (IL‐1‐beta, IL‐2, IL‐4, IL‐5, IL‐6, IL‐8/CXCL8, IL‐10, IL‐12p70, IL‐13, IL‐17A, GM‐CSF, TNF ...
Albert Aboseif+17 more
wiley +1 more source
Introduction: There are some reports in traditional medicine concerning the anti-inflammatory, anti-nociceptive and anti-pyretic effects of Trifolium pretense (red clover).
Parandin R
doaj
Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model
IntroductionTo investigate the metabolism and distribution of iPSC‐MSCs in the joint cavity of rats with knee osteoarthritis (KOA).MethodsThe iPSC‐MSCs labeled with the Antares2 luciferase gene were injected into the knee joints of rats, and then the ...
Xiaoyang Yuan+13 more
doaj +1 more source
Partial purification of the anti‐inflammatory factor(s) in inflammatory exudate [PDF]
M. E. J. Billingham+2 more
openalex +1 more source
Effects of Non‐Aspirin Nonsteroidal Anti‐Inflammatory Drugs on Acute Intracerebral Hemorrhage
ABSTRACT Objective Despite celecoxib, a cyclooxygenase‐2 inhibitor, promoting functional recovery from intracerebral hemorrhage (ICH) by reducing inflammation‐mediated perihematomal edema in rat models, the evidence of its effects on patient outcomes remains limited.
Shin‐Joe Yeh+3 more
wiley +1 more source
Anti‐inflammatory activity of the steroid alkaloid glycoside, tomatine [PDF]
R. B. FILDERMAN, Béla Kovács
openalex +1 more source
Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald+74 more
wiley +1 more source
Anti-inflammatory Activity Of Bawang Dayak (Eleutherine Bulbosa (Mill. Urb.))ethanol Bulb Extracts [PDF]
Background: Inflammation is a normal process in response to injury, but causes problems for the patient, including the appearance of pain, swelling, or fever.
Nuryanto, M. K. (Muhammad)+1 more
core
Anti-inflammatory property of propolis
Dear Editor-in-Chief, The recent article by Weina Gao and colleagues, on July issue of this Journal, showed that Brazilian green propolis have a positive effect on innate and adaptive immunity in aged mice.(1) This role should be mainly attributed to flavonoids contained in propolis.(2) The Authors reported that Brazilian propolis had 189.12 mg/g ...
openaire +4 more sources
Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin+10 more
wiley +1 more source