Results 131 to 140 of about 149 (149)
Some of the next articles are maybe not open access.
Pain control: Non-steroidal anti-inflammatory agents
Seminars in Fetal and Neonatal Medicine, 2006The non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen (paracetamol) are the most common analgesic drugs used in neonates and infants despite limited pharmacodynamic data. Both drugs act through inhibition of cyclooxygenase enzymes. Neonatal acetaminophen clearance is reduced in premature neonates (0.7 L h(-1) x 70 kg(-1)) and increases ...
Brian J. Anderson, Evelyne Jacqz-Aigrain
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Non-steroidal Anti-inflammatory Agents and the Skin
1989The development of topical non-steroidal anti-inflammatory drugs (NSAIDs), devoid of the unwanted effects of corticosteroids but with equal or even greater potency, has been an unattained ideal for many years. Considerable impetus was given to the search by the discovery by Vane (1971) that aspirin and other NSAIDs owed their effectiveness, at least in
M. W. Greaves, S. Shuster
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Antimicrobial Activity of Benzydamine, a Non-Steroid Anti-Inflammatory Agent
Journal of Chemotherapy, 1992The antimicrobial activity of benzydamine (BD), a non-steroid anti-inflammatory agent, was studied using different techniques against 38 strains belonging to 12 microbial species comprising bacteria, yeasts and a fungus. The minimum inhibitory concentrations, minimum lethal concentrations, per cent survivors after 30-minute exposure to BD (0.1 ...
N.H. Fanaki, M.A. El-Nakeeb
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The selection of non-steroidal anti-inflammatory agents for dermal delivery
International Journal of Pharmaceutics, 2000An analysis has been conducted to show how the penetration of a selection of non-steroidal anti-inflammatory agents (NSAIDs) through the skin may be predicted. The calculations are based on physicochemical parameters that can be predicted using commercially available software.
Jeanetta du Plessis +2 more
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OBSERVATIONS ON THE INTERACTIONS BETWEEN NON‐STEROID ANTI‐INFLAMMATORY AGENTS AND CORTICOSTEROIDS*
Australasian Journal of Dermatology, 1978SummaryWe have shown that corticosteroids and non‐steroid anti‐inflammatory agents suppress the increase in skin thickness in response to irritants applied to guinea pig skin. The combination of salicylic acid with corticosteroids and acetyl salicylic acid with hydrocortisone results in an antagonistic reduction of their anti‐inflammatory activities ...
P. M. Gaylarde, A.P. Brock, I. Sarkany
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Use of non-steroidal anti-inflammatory drugs (NSAIDs) as immunomodulatory agents [PDF]
BMJ, 2013 I was delighted to see the BMJ Therapeutics series covering non-steroidal anti-inflammatory agents—a class of drugs that has perhaps been unfairly maligned and shunned recently.1 Although the article focused on the use of these drugs as analgesics, they can be used as immunomodulatory agents.
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Chapter 19. Non-steroidal Anti-inflammatory Agents
1969Publisher Summary This chapter elaborates studies analyzing non-steroidal anti-inflammatory agents. The importance of the circulating lymphocyte in association with the auto-immune component of adjuvant disease was shown by studies with heterologous antirat lymphocyte serum which prevents secondary responses to complete adjuvant. The RNA/DNA ratio of
Jan W. F. Wasley +5 more
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Chapter 25. Non-steroidal Anti-inflammatory Agents
1970Publisher Summary This chapter elaborates the development and clinical studies of nonsteroidal anti-inflammatory agents. The studies of the possible role of infectious inductions and/or adverse immunological reactions continue with the hope of defining the trigger mechanism for the chronic and self-perpetuating inflammatory processes in man.
Jan W. F. Wasley +5 more
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In vivo suppression of prostaglandin biosynthesis by non-steroidal anti-inflammatory agents
Prostaglandins, 1976In vivo effects of orally administered inhibitors on prostaglandin and F levels were determined in seven organs of the rat. Ibuprofen showed suppression in most tissues three hours after dosing with a return to control values by twenty-four hours. Flurbiprofen and indomethacin showed potent suppression at both three and twenty-four hours after dosing ...
M.A. Wynalda, F.A. Fitzpatrick
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